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Volumn 16, Issue 5, 1986, Pages 449-464
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The molecular mechanisms of two common polymorphisms of drug oxidation-evidence for functional changes in cytochrome p-450 isozymes catalysing bufuralol and mephenytoin oxidation
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Author keywords
[No Author keywords available]
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Indexed keywords
1' HYDROXYBUFURALOL;
BUFURALOL;
CYTOCHROME P450 ISOENZYME;
DEBRISOQUINE;
MEPHENYTOIN;
METOPROLOL;
UNCLASSIFIED DRUG;
ARTICLE;
DRUG ANALYSIS;
DRUG BLOOD LEVEL;
DRUG COMPARISON;
DRUG DETERMINATION;
DRUG ELIMINATION;
DRUG IDENTIFICATION;
DRUG METABOLISM;
DRUG PURIFICATION;
DRUG URINE LEVEL;
ENANTIOMER;
HEREDITY;
HUMAN;
HUMAN CELL;
HUMAN EXPERIMENT;
IN VITRO STUDY;
LIVER;
NORMAL HUMAN;
ORAL DRUG ADMINISTRATION;
POLYMORPHISM;
PRIORITY JOURNAL;
ADRENERGIC BETA-ANTAGONISTS;
CYTOCHROME P-450 ENZYME SYSTEM;
ETHANOLAMINES;
HUMANS;
HYDANTOINS;
HYDROXYLATION;
ISOENZYMES;
KINETICS;
MEPHENYTOIN;
METOPROLOL;
MICROSOMES, LIVER;
OXIDATION-REDUCTION;
POLYMORPHISM, GENETIC;
STRUCTURE-ACTIVITY RELATIONSHIP;
TISSUE DONORS;
VARIATION (GENETICS);
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EID: 0022899555
PISSN: 00498254
EISSN: None
Source Type: Journal
DOI: 10.3109/00498258609050251 Document Type: Article |
Times cited : (134)
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References (29)
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