PERSISTENT EFFECTS ON BLOOD PRESSURE AND RENAL HAEMODYNAMICS FOLLOWING CHRONIC ANGIOTENSIN CONVERTING ENZYME INHIBITION WITH PERINDOPRIL

Clinical and Experimental Pharmacology and Physiology

Volumn 13, Issue 11-12, 1986, Pages 753-765

  Harrap, Stephen B ^a   Nicolaci, Joseph A ^a   Doyle, Austin E ^a  

^a UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

angiotensin converting enzyme; blood pressure; Perindopril; renal haemodymanics; SHR.; total body sodium

Indexed keywords

DIPEPTIDYL CARBOXYPEPTIDASE; PERINDOPRIL;

ANIMAL MODEL; BLOOD PRESSURE; CARDIOVASCULAR SYSTEM; DRUG EFFICACY; ENZYME INHIBITION; KIDNEY; KIDNEY BLOOD FLOW; NATRIURESIS; NONHUMAN; ORAL DRUG ADMINISTRATION; PERIPHERAL VASCULAR SYSTEM; PRIORITY JOURNAL; RAT;

ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; ANIMAL; ANTIHYPERTENSIVE AGENTS; BLOOD FLOW VELOCITY; BLOOD PRESSURE; FEMALE; GLOMERULAR FILTRATION RATE; HYPERTENSION; INDOLES; MALE; MYOCARDIUM; ORGAN WEIGHT; PERINDOPRIL; RATS; RATS, INBRED SHR; RATS, INBRED WKY; RENAL CIRCULATION; SODIUM; VASCULAR RESISTANCE;

EID: 0022897159     PISSN: 03051870     EISSN: 14401681     Source Type: Journal    
DOI: 10.1111/j.1440-1681.1986.tb02379.x     Document Type: Article

References (26)

1. Contribution of the kidneys but not the adrenal glands to the acute antihypertensive effects of captopril in spontaneously hypertensive rats
2. Validation in awake rats of a tail‐cuff method for measuring systolic pressure
3. Angiotensin converting enzyme inhibition in tissues from spontaneously hypertensive rats after treatment with captopril or MK‐421
4. Comparison of the actions of the angiotensin‐converting enzyme inhibitors enalapril and Perindopril in sodium‐deplete and sodium‐replete spontaneously hypertensive rats
5. Prevention of the development of spontaneous hypertension in rats by captopril (SQ 14, 225)
6. Captopril and hypertension development in the SHR
7. Sodium intake, exchangeable sodium and body fluid volume in spontaneously hypertensive rats
8. Total body sodium in immature spontaneously hypertensive and Wistar Kyoto rats
9. Renal haemodynamics and exchangeable sodium in the spontaneously hypertensive rat
10. Hemodynamic characterization of hypertension induced by chronic intrarenal or intravenous infusion of norepinephrine in conscious rats
11. Effects of long‐term blockade of angiotensin converting enzyme with captopril (SQ 14,225) on hemodynamics and circulating blood volume in SHR
12. Effects of captopril on urinary excretion of prostaglandins and electrolytes in spontaneously hypertensive rats
13. Antihypertensive action of the orally active converting enzyme inhibitor (SQ 14,225) in spontaneously hypertensive rats
14. Effect of methyldopa, clonidine and hydralazine on cardiac mass and hemodynamics in Wistar Kyoto and spontaneously hypertensive rats
15. Genetics of experimental and human hypertension
16. MK 421 and prevention of genetic hypertension development in young spontaneously hypertensive rats
17. Influence of captopril and enalapril on regional vascular alpha‐adrenergic receptor reactivity in SHR
18. Nutrition
19. Systemic and regional hemodynamics following acute inhibition of angiotensin 1‐converting enzyme in the conscious spontaneously hypertensive rat
20. Preferential renal vasodilator effects of CGP 22979A in conscious spontaneously hypertensive rats
21. Antihypertensive activity of N‐[(S)‐(ethoxycarbonyl)‐3‐phenylpropyl]‐L‐Ala‐L‐Pro(MK‐421), an orally active converting enzyme inhibitor
22. Persistent tissue converting enzyme inhibition following chronic treatment with Hoe498 and MK421 in spontaneously hypertensive rats