Enhanced expression of the n-myc gene in wilms’ tumors

Cancer Research

Volumn 46, Issue , 1986, Pages 6217-6222

  Nisen, Perry D ^a   Zimmerman, Kathryn A ^b   Cotter, Sean V ^b   Gilbert, Fred ^b   Alt, Frederick W ^b  

^a STONY BROOK UNIVERSITY   (United States)

^b MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHILD; ETIOLOGY; GENE EXPRESSION; GENETIC ENGINEERING; HEPATOBLASTOMA; HUMAN; HUMAN CELL; KIDNEY; KIDNEY PARENCHYMA; MEDULLOBLASTOMA; NEPHROBLASTOMA; ONCOGENE C MYC; PRIORITY JOURNAL;

FETUS; GENE AMPLIFICATION; HUMANS; INSULIN-LIKE GROWTH FACTOR II; KIDNEY; KIDNEY NEOPLASMS; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-MYC; PROTO-ONCOGENES; RNA; WILMS TUMOR;

EID: 0022848633     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: None     Document Type: Article

References (38)

1. Alt, F., DePinho, R., Zimmerman, K., Legouy, E., Hatton, K., Ferrier, P., Tesfaye, A., Yancopoulos, G., and Nisen, P. The human myc gene family. Cold Spring Harbor Symp. Quant. Biol., in press, 1986.
2. Kohl, N.E., Legouy, E., De Pinho, R.A., Nisen, P.D., Smith, R.K., Gee, C.E., and Alt, F.W. Human N-myc is closely related in organization and sequence to c-myc. Nature (Lond.), 319:73-77, 1986.
3. DePinho, R., Leguoy, E., Feldman, L., Kohl, N., Yancopoulos, G., and Alt, F. Structure and expression of the murine N-myc gene. Proc. Natl. Acad. Sci. USA, 83:1827-1831, 1986.
4. Yancopoulos, G., Nisen, P., Tesfaye, A., Kohl, N., Goldfarb, M., and Alt, F. N-myc can cooperate with ras to transform normal cells in culture. Proc. Natl. Acad. Sci. USA, 82:5455-5459, 1985.
5. Schwab, M., Varmus, H., and Bishop, M. Human N-myc gene contributes to neoplastic transformation of mammalian cells in culture. Nature (Lond.), 316:160-163,1985.
6. Nau, M.M., Brooks, B., Battey, J., Sausville, E., Gazdar, A., Kirsch, I., McBride, O., Bertness, V., Hollis, G., and Minna, J. L-myc, a new mycrelated gene amplified and expressed in human small cell lung carcinoma. Nature (Lond.), 318:69-73, 1985.
7. Zimmerman, K., Yancopoulos, G., Collum, R., Smith, R., Kohl, N., Denis, K., Nau, M., Witte, O., Toran-Allerand, D., Gee, C., Minna, J., and Alt, F. Differential expression of myc family genes during murine development. Nature (Lond.), 319:780-783,1986.
8. Kohl, N., Kanda, N., Schreck, R., Bruns, G., Latt, S., Gilbert, F., and Alt, F. Transposition and amplification of oncogene-related sequences in human neuroblastomas. Cell, 35:359-367, 1983.
9. Schwab, M., Alitalo, K., Klempnauer, L., Varmus, H., Bishop, J.M., Gilbert, F., Brodeur, G., Goldstein, M., and Trent, J. Amplified DNA with limited homology to myc cellular oncogene is shared by human neuroblastoma cell lines and a neuroblastoma tumor. Nature (Lond.), 305:245-248,1983.
10. Schwab, M., Ellison, J., Busch, M., Rosenau, W., Varmus, H., and Bishop, J.M. Enhanced expression of the human gene N-myc consequent to amplification may contribute to malignant progression of neuroblastoma. Proc. Natl. Acad. Sci. USA, 81:4940-4944, 1984.
11. Kohl, N., Gee, C., and Alt, F. Activated expression of the N-myc gene in human neuroblastomas and related tumors. Science (Wash. DC), 226:1335-1337, 1984.
12. Lee, W., Murphree, A., and Benedict, W. Expression and amplification of the N-myc gene in primary retinoblastoma. Nature (Lond.), 309: 458–460, 1984.
13. Nau, M., Brooks, S., Carney, D., Gazder, A., Battey, J., Sausville, E., and Minna, J. Human small cell lung carcinomas show amplification and expression of the N-myc gene. Proc. Natl. Acad. Sci. USA, 83:1092-1096, 1986.
14. Varmus, H. The molecular genetics of cellular oncogenes. Annu. Rev. Genet., 18:553-612, 1984.
15. Dalla-Favera, R., Wong-Staal, F., and Gallo, R.C. Onc gene amplification in promyelocytic leukemia cell line HL-60 and primary leukemic cells of the same patient. Nature (Lond.), 299:61-63, 1982.
16. Ravetch, J., Siebenlist, J., Korsmeyer, S., Waldmann, T., and Leder, P. Human immunoglobulin segments encoded in tandem multigenic families. Nature (Lond.), 294:631-635,1981.
17. McAllister, R., Isaacs, H., Rongey, R., Peer, M., Au, W., Soukup, S., and Gardner, M. Establishment of a human medulloblastoma cell line. Int.J. Cancer, 20: 206–212, 1977.
18. Seeger, R., Brodeur, G., Sather, H., Dalton, A., Siegel, S., Wong, K., and Hammond, O. Association of multiple copies of the N-myc oncogene with rapid progression of neuroblastomas.N. Engl.J. Med., 313: 1111–1116, 1985.
19. Jakobovits, A., Schwab, M., Bishop, J.M., and Martin, G.R. Expression of N-myc in teratocarcinoma stem cells and mouse embryo. Nature (Lond.), 318: 188–191, 1985.
20. Brodeur, G., Seeger, R., Schwab, M., Varmus, H., and Bishop, J.M. Amplification of N-myc in untreated neuroblastomas correlates with advanced disease stage. Science (Wash. DC), 224: 1121–1124, 1984.
21. Squire, J., Goddard, A., Canton, A., Becker, A., Phillips, A., and Gallie, B. Tumour induction by the retinoblastoma mutation is independent of N-myc gene expression. Nature (Lond.), 322:555-557, 1986.
22. Knudson, A. Hereditary cancer, oncogenes, and antioncogenes. Cancer Res., 45: 1437–1443, 1985.
23. Murphree, A., and Benedict, W. Retinoblastoma: clues to human oncogenesis. Science (Wash. DC), 223:1028-1033, 1984.
24. Klein, G., and Klein, E. Evolution of tumours and the impact of molecular oncology. Nature (Lond.), 315: 190–195, 1985.
25. Knudson, A., and Strong, L.J. Mutation and cancer: a model for Wilms’ tumor of the kidney.J. Natl. Cancer Inst., 48: 313–324, 1972.
26. Comings, D. A general theory of carcinogenesis. Proc. Natl. Acad. Sci. USA, 70: 3324–3328, 1973.
27. Reeve, A.E., Eccles, M.R., Wilkins, R.J., Bell, G.I., and Millow, L.J. Expression of insulin-like growth factor-II transcripts in Wilms’ tumour. Nature (Lond.), 317: 258–260, 1985.
28. Scott, J., Cowell, J., Robertson, M., Priestly, L., Wadey, R., Hopkins, B., Pritchard, J., Bell, G., Rail, L., Graham, C., and Knott, T. Insulin-like growth factor-II gene expression in Wilms’ tumour and embryonic tissues. Nature (Lond.), 317: 260–262, 1985.
29. Adams, S.O., Nissley, S.P., Handwerger, S., and Redder, M.M. Developmental patterns of insulin-like growth factor-I and -II synthesis and regulation in rat fibroblasts. Nature (Lond.), 302: 150–153, 1983.
30. Donner, P., Greiser-Wilke, I., and Moelling, K. Nuclear localization and DNA binding of the transforming gene product of avian myelocytomatosis virus. Nature (Lond.), 296:262-266, 1982.
31. Persson, H., and Leder, P. Nuclear localization and DNA binding properties of a protein expressed by the human c-myc oncogene. Science (Wash. DC), 225:718-721, 1984.
32. Watt, R.A., Shatzman, A.R., and Rosenberg, M. Expression and characterization of the human c-myc DNA binding protein. Mol. Cell. Biol., 5: 448–456, 1985.
33. Eisenman, R.N., Tachibana, C., Abrams, H., and Hann, S. V-myc and c-myc encoded proteins are associated with the nuclear matrix. Mol. Cell. Biol., 5: 114–126, 1985.
34. Armelin, H.A., Armelin, M., Kelly, K., Stewart, T., Leder, P., Cochran, B., and Stiles, C. Functional role for c-myc in mitogenic response to platelet-derived growth factor. Nature (Lond.), 310:655-670, 1984.
35. Ralston, R.T., and Bishop, J.M. The protein products of the myc and myb oncogenes and adenovirus are structurally related. Nature (Lond.), 306:803-806, 1983.
36. Klein, G. The role of gene dosage and genetic transpositions in carcinogenesis. Nature (Lond.), 294: 313–318, 1981.
37. Kelly, K., Cochran, B., Stiles, C., and Leder, P. Cellspecific regulation of the c-myc gene by lymphocyte mitogens and platelet-derived growth factor. Cell, 35:603-610, 1983.
38. Saito, H., Hayday, A., Hayward, W., and Tonegawa, S. Activation of the c-myc gene by translocation: a model for translational control. Proc. Natl. Acad. Sci. USA, 80: 7476-7480,1983.