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Volumn 7, Issue 1, 1986, Pages 3-10

The molecular basis of gonadotropin-releasing hormone action

Author keywords

[No Author keywords available]

Indexed keywords

AMINOQUINOLINE DERIVATIVE; CALCIUM; CALMODULIN; CELL SURFACE RECEPTOR; DIACYLGLYCEROL; GONADORELIN RECEPTOR; HYPOTHALAMUS RELEASING FACTOR; INOSITOL PHOSPHATE; LUTEINIZING HORMONE; PHORBOL 13 ACETATE 12 MYRISTATE; PHOSPHATIDYLINOSITOL; PITUITARY HORMONE RELEASING HORMONES; PROTEIN KINASE C; QUIN2;

EID: 0022668418     PISSN: 0163769X     EISSN: 0163769X     Source Type: Journal    
DOI: 10.1210/edrv-7-1-3     Document Type: Article
Times cited : (109)

References (73)
  • 2
    • 0020650699 scopus 로고
    • Subcellular localization of the receptor for gonadotropin-releasing hormone in pituitary and ovarian tissue
    • Marian J, Conn PM 1983 Subcellular localization of the receptor for gonadotropin-releasing hormone in pituitary and ovarian tissue. Endocrinology 112:104
    • (1983) Endocrinology , vol.112 , pp. 104
    • Marian, J.1    Conn, P.M.2
  • 4
    • 0018168286 scopus 로고
    • Hypophyseal responses to continuous and intermittent delivery of hypothalamic gnrh
    • Belchetz PE, Plant TM, Nakai Y, Keogh EJ, Knobil E 1978 Hypophyseal responses to continuous and intermittent delivery of hypothalamic GnRH. Science 202:631
    • (1978) Science , vol.202 , pp. 631
    • Belchetz, P.E.1    Plant, T.M.2    Nakai, Y.3    Keogh, E.J.4    Knobil, E.5
  • 5
    • 0015378131 scopus 로고
    • Culture of enzymatically dispersed anterior pituitary cells: functional validation of a method
    • Vale W, Grant G, Amoss M, Blackwell R, Guillemin R 1972 Culture of enzymatically dispersed anterior pituitary cells: functional validation of a method. Endocrinology 91:562
    • (1972) Endocrinology , vol.91 , pp. 562
    • Vale, W.1    Grant, G.2    Amoss, M.3    Blackwell, R.4    Guillemin, R.5
  • 6
    • 0017722417 scopus 로고
    • Estrogen regulation of fsh in cell cultures of sheep pituitaries
    • Miller WL, Knight MM, Grimek HJ, Gorski J 1977 Estrogen regulation of FSH in cell cultures of sheep pituitaries. Endocrinology 100:1306
    • (1977) Endocrinology , vol.100 , pp. 1306
    • Miller, W.L.1    Knight, M.M.2    Grimek, H.J.3    Gorski, J.4
  • 7
    • 0018033066 scopus 로고
    • Dissociation of the porcine anterior pituitary: The kinetics of lh release in response to lhrh
    • Walker AM, Hopkins CR 1978 Dissociation of the porcine anterior pituitary: the kinetics of LH release in response to LHRH. Mol Cell Endocrinol 12:177
    • (1978) Mol Cell Endocrinol , vol.12 , pp. 177
    • Walker, A.M.1    Hopkins, C.R.2
  • 8
    • 85003140902 scopus 로고
    • Gnrh-stimulated release of lh from rat pituicytes does not require production of cyclic amp
    • Conn PM, Dufau ML, Catt KJ 1979 GnRH-stimulated release of LH from rat pituicytes does not require production of cyclic AMP. Endocrinology 104:448
    • (1979) Endocrinology , vol.104 , pp. 448
    • Conn, P.M.1    Dufau, M.L.2    Catt, K.J.3
  • 9
    • 0019540090 scopus 로고
    • Gonadotropin-releasing hormone receptors: Characterization, physiological regulation and relationship to reproductive function
    • Clayton RN, Catt KJ 1981 Gonadotropin-releasing hormone receptors: characterization, physiological regulation and relationship to reproductive function. Endocr Rev 2:186
    • (1981) Endocr Rev , vol.2 , pp. 186
    • Clayton, R.N.1    Catt, K.J.2
  • 10
    • 0018772219 scopus 로고
    • Gnrh stimulation of cultured pituitary cells requires calcium
    • Marian J, Conn PM 1979 GnRH Stimulation of cultured pituitary cells requires calcium. Mol Pharmacol 16: 196
    • (1979) Mol Pharmacol , vol.16 , pp. 196
    • Marian, J.1    Conn, P.M.2
  • 11
    • 0019305084 scopus 로고
    • The calcium requirement in gnrhstimulted lh release is not mediated through a specific action on the receptor
    • Marian J, Conn PM 1980 The calcium requirement in GnRHstimulted LH release is not mediated through a specific action on the receptor. Life Sci 27:87
    • (1980) Life Sci , vol.27 , pp. 87
    • Marian, J.1    Conn, P.M.2
  • 12
    • 0018379329 scopus 로고
    • Restoration of responsiveness of gonadotropin releasing hormone (Gnrh) in calcium depleted rat pituitary cells
    • Conn PM, Rogers DC 1979 Restoration of responsiveness of gonadotropin releasing hormone (GnRH) in calcium depleted rat pituitary cells. Life Sci 24:2461
    • (1979) Life Sci , vol.24 , pp. 2461
    • Conn, P.M.1    Rogers, D.C.2
  • 13
    • 0021161777 scopus 로고
    • Calcium mobilization in the pituitary gonadotrope: Relative roles of intraand extracellular sources
    • Bates MD, Conn PM 1984 Calcium mobilization in the pituitary gonadotrope: relative roles of intraand extracellular sources. Endocrinology 115:1380
    • (1984) Endocrinology , vol.115 , pp. 1380
    • Bates, M.D.1    Conn, P.M.2
  • 14
    • 0020591379 scopus 로고
    • Structure-function relationships of calcium ion channel antagonists at the pituitary gonadotrope
    • Conn PM, Rogers DC, Seay SG 1983 Structure-function relationships of calcium ion channel antagonists at the pituitary gonadotrope. Endocrinology 113:1592
    • (1983) Endocrinology , vol.113 , pp. 1592
    • Conn, P.M.1    Rogers, D.C.2    Seay, S.G.3
  • 15
    • 0019068740 scopus 로고
    • Calcium antagonists and hormone release. Ii. effects of verapamil on basal, gonadotropin-releasing hormone-induced pituitary hormone release in normal subjects
    • Barbarino A, DeMarinis L 1980 Calcium antagonists and hormone release. II. Effects of verapamil on basal, gonadotropin-releasing hormone-induced pituitary hormone release in normal subjects. J Clin Endocrinol Metab 51:749
    • (1980) J Clin Endocrinol Metab , vol.51 , pp. 749
    • Barbarino, A.1    DeMarinis, L.2
  • 16
    • 0018604046 scopus 로고
    • Alteration of intracellular calcium level stimulates gonadotropin release from cultured rat pituitary cells
    • Conn PM, Rogers DC, Sandhu FS 1979 Alteration of intracellular calcium level stimulates gonadotropin release from cultured rat pituitary cells. Endocrinology 105:1122
    • (1979) Endocrinology , vol.105 , pp. 1122
    • Conn, P.M.1    Rogers, D.C.2    Sandhu, F.S.3
  • 18
    • 0019201238 scopus 로고
    • Gonadotropin release from pituitary cultures following activation of endogenous ion channels
    • Conn PM, Rogers DC 1980 Gonadotropin release from pituitary cultures following activation of endogenous ion channels. Endocrinology 107:2133
    • (1980) Endocrinology , vol.107 , pp. 2133
    • Conn, P.M.1    Rogers, D.C.2
  • 19
    • 0019162406 scopus 로고
    • Evidence for calcium mediation of gonadotropin releasing hormone action in the pituitary
    • Conn PM, Marian J, McMillian M, Rogers D 1980 Evidence for calcium mediation of gonadotropin releasing hormone action in the pituitary. Cell Calcium 1:7
    • (1980) Cell Calcium , vol.1 , pp. 7
    • Conn, P.M.1    Marian, J.2    McMillian, M.3    Rogers, D.4
  • 20
    • 0017100504 scopus 로고
    • Stimulation of 46ca2+ efflux from rat pituitary by lhrh and other pituitary stimulators
    • 2+ efflux from rat pituitary by LHRH and other pituitary stimulators. J Physiol (Lond) 260:105
    • (1976) J Physiol (Lond) , vol.260 , pp. 105
    • Williams, J.A.1
  • 21
    • 0021920519 scopus 로고
    • Gnrh stimulation of pituitary gonadotrope cells produces an increase in intracellular calcium
    • Clapper D, Conn PM 1985 GnRH stimulation of pituitary gonadotrope cells produces an increase in intracellular calcium. Biol Reprod 32:269
    • (1985) Biol Reprod , vol.32 , pp. 269
    • Clapper, D.1    Conn, P.M.2
  • 22
    • 0019319345 scopus 로고
    • Calmodulin: An intracellular calcium receptor
    • Means AR, Dedman JR 1980 Calmodulin: an intracellular calcium receptor. Nature 285:73
    • (1980) Nature , vol.285 , pp. 73
    • Means, A.R.1    Dedman, J.R.2
  • 23
    • 0018872612 scopus 로고    scopus 로고
    • Calmodulin plays a pivotal role in cellular regulation
    • Cheung WY 1980 Calmodulin plays a pivotal role in cellular regulation. Science 207: 19
    • Science
    • Cheung, W.Y.1
  • 24
    • 0019723434 scopus 로고
    • Gonadotropin releasing hormone stimulates calmodulin redistribution in the rat pituitary
    • Conn PM, Chafouleas J, Rogers D, Means AR 1981 Gonadotropin releasing hormone stimulates calmodulin redistribution in the rat pituitary. Nature 292:264
    • (1981) Nature , vol.292 , pp. 264
    • Conn, P.M.1    Chafouleas, J.2    Rogers, D.3    Means, A.R.4
  • 25
    • 0021985481 scopus 로고
    • Evidence for an association between calmodulin and membrane patches containing gnrh-receptor in cultured pituitary gonadotropes
    • Jennes L, Bronson D, Stumpf WE, Conn PM 1985 Evidence for an association between calmodulin and membrane patches containing GnRH-receptor in cultured pituitary gonadotropes. Cell Tissue Res 239:311
    • (1985) Cell Tissue Res , vol.239 , pp. 311
    • Jennes, L.1    Bronson, D.2    Stumpf, W.E.3    Conn, P.M.4
  • 26
    • 0019517592 scopus 로고
    • Inhibition of gonadotropin releasing hormone stimulated luteinizing hormone release by pimozide: Evidence for a site of action after calcium mobilization
    • Conn PM, Rogers DC, Sheffield T 1981 Inhibition of gonadotropin releasing hormone stimulated luteinizing hormone release by pimozide: evidence for a site of action after calcium mobilization. Endocrinology 109:1122
    • (1981) Endocrinology , vol.109 , pp. 1122
    • Conn, P.M.1    Rogers, D.C.2    Sheffield, T.3
  • 28
    • 0020643733 scopus 로고
    • Synthesis and characterization of calmodulin antagonistic drugs
    • O’Malley B, Means A (eds), Academic Press, New York
    • Hart R, Bates MD, Cormier MJ, Rosen GM, Conn PM 1983 Synthesis and characterization of calmodulin antagonistic drugs. In: O’Malley B, Means A (eds) Methods in Enzymology: Calmodulin. Academic Press, New York, vol 102: 195
    • (1983) Methods in Enzymology: Calmodulin , vol.102 , pp. 195
    • Hart, R.1    Bates, M.D.2    Cormier, M.J.3    Rosen, G.M.4    Conn, P.M.5
  • 29
    • 0019522686 scopus 로고
    • Mechanism of action of gnrh, involvement of phospholipid turnover in lh release
    • Naor Z, Catt KJ 1981 Mechanism of action of GnRH, involvement of phospholipid turnover in LH release. J Biol Chem 256:2226
    • (1981) J Biol Chem , vol.256 , pp. 2226
    • Naor, Z.1    Catt, K.J.2
  • 30
    • 0019947278 scopus 로고
    • Effect of lhrh on incorporation of [32p]orthophosphate into phosphatidylinositol by dispersed pituitary cells
    • 32P]orthophosphate into phosphatidylinositol by dispersed pituitary cells. Mol Cell endocrinol 28:55
    • (1982) Mol Cell Endocrinol , vol.28 , pp. 55
    • Synder, G.D.1    Bleasdale, J.E.2
  • 31
    • 85003073035 scopus 로고    scopus 로고
    • Nrh stimulates mass changes in phosphoinositides and diacylglycerol accumulation in purified gonadotrope cell culture
    • press
    • Andrews, WV, Conn PM, GnRh stimulates mass changes in phosphoinositides and diacylglycerol accumulation in purified gonadotrope cell culture. Endocrinology, in press
    • Endocrinology
    • Andrews, W.V.1    Conn, P.M.2
  • 32
    • 0020326211 scopus 로고
    • Direct interaction of mepacrine with erythrocyte and platelet membrane phospholipid
    • Dise CA, Burch JW, Goodman DBP 1982 Direct interaction of mepacrine with erythrocyte and platelet membrane phospholipid. J Biol Chem 257:4701
    • (1982) J Biol Chem , vol.257 , pp. 4701
    • Dise, C.A.1    Burch, J.W.2    Goodman, D.3
  • 34
    • 0021227676 scopus 로고
    • The role of protein kinase c in cell surface
    • Nishizuka T 1984 The role of protein kinase C in cell surface transduction and tumor promotion. Nature 308:693
    • (1984) Nature
    • Nishizuka, T.1
  • 36
    • 0021328918 scopus 로고    scopus 로고
    • Microaggregation of the gnrh-receptor stimulates gonadotrope desensitization
    • Smith WA, Conn PM 1984 Microaggregation of the GnRH-receptor stimulates gonadotrope desensitization. Endocrinology 114:553
    • (1984) Endocrinology , vol.114 , pp. 553
    • Smith, W.A.1    Conn, P.M.2
  • 37
    • 0019505532 scopus 로고
    • Densensitization to gonadotropinreleasing hormone observed in superfused pituitary cells on cytodex beads
    • Smith MA, Vale WW 1981 Densensitization to gonadotropinreleasing hormone observed in superfused pituitary cells on cytodex beads. Endocrinology 108:752
    • (1981) Endocrinology , vol.108 , pp. 752
    • Smith, M.A.1    Vale, W.W.2
  • 39
    • 0021951129 scopus 로고
    • Diacylglycerols and protein kinase c: Potential amplifying mechanism for ca2+-mediated gnrh stimulated lh release
    • 2+-mediated GnRH stimulated LH release. Mol Pharmacol 27:532
    • (1986) Mol Pharmacol , vol.27 , pp. 532
    • Harris, C.E.1    Conn, P.M.2    Staley, D.3
  • 40
    • 26344450998 scopus 로고    scopus 로고
    • Pi turnover in response to gnrh: Independence of ca2+-calmodulin and lh release
    • 2+-calmodulin and LH release. J Cell Biol 101:4a
    • J Cell Biol , vol.101 , pp. 4a
    • Huckle, W.R.1    Conn, P.M.2
  • 41
    • 0018642104 scopus 로고
    • Radioiodinated nondegradable gnrh analogs: New probes for the investigation of pituitary gnrh receptors
    • Clayton RN, Shakespear RA, Duncan JA, Marshall JC 1979 Radioiodinated nondegradable GnRH analogs: new probes for the investigation of pituitary GnRH receptors. Endocrinology 105:1369
    • (1979) Endocrinology , vol.105 , pp. 1369
    • Clayton, R.N.1    Shakespear, R.A.2    Duncan, J.A.3    Marshall, J.C.4
  • 42
    • 0019445592 scopus 로고
    • Regulation of the rat pituitary gnrh-receptor
    • Marian J, Cooper R, Conn PM 1981 Regulation of the rat pituitary GnRH-receptor. Mol Pharmacol 19:399
    • (1981) Mol Pharmacol , vol.19 , pp. 399
    • Marian, J.1    Cooper, R.2    Conn, P.M.3
  • 44
    • 0019511376 scopus 로고    scopus 로고
    • Pituitary gnrh receptors: Effects of castration, steroid replacement, and the role of gnrh in modulating receptors in the rat
    • Frager MS, Pieper DR, Tonetta JA, Marshall JC 1981 Pituitary GnRH receptors: effects of castration, steroid replacement, and the role of GnRH in modulating receptors in the rat. J Clin Invest 67:615
    • (1981) J Clin Invest , vol.67 , pp. 615
    • Frager, M.S.1    Pieper, D.R.2    Tonetta, J.A.3    Marshall, J.C.4
  • 46
    • 0019312968 scopus 로고
    • Pituitary gonadotropin-releasing hormone receptors during the rat estrous cycle
    • Savoy-Moore RT, Schwartz NB, Duncan JA, Marshall JC 1980 Pituitary gonadotropin-releasing hormone receptors during the rat estrous cycle. Science 209:924
    • (1980) Science , vol.209 , pp. 924
    • Savoy-Moore, R.T.1    Schwartz, N.B.2    Duncan, J.A.3    Marshall, J.C.4
  • 47
    • 0015968605 scopus 로고
    • Changes in the sensitivity of the pituitary gland to luteinizing hormone releasing factor during the estrous cycle of the rat
    • Aiyer MS, Fink G, Greig F 1974 Changes in the sensitivity of the pituitary gland to luteinizing hormone releasing factor during the estrous cycle of the rat. J Endocrinol 60:47
    • (1974) J Endocrinol , vol.60 , pp. 47
    • Aiyer, M.S.1    Fink, G.2    Greig, F.3
  • 48
    • 0020678136 scopus 로고
    • Coincidence of down-regulation and desensitization in pituitary gonadotrophs stimulated by gonadotropin releasing hormone
    • Zilberstein M, Zakut H, Naor Z 1983 Coincidence of down-regulation and desensitization in pituitary gonadotrophs stimulated by gonadotropin releasing hormone. Life Sci 32:663
    • (1983) Life Sci , vol.32 , pp. 663
    • Zilberstein, M.1    Zakut, H.2    Naor, Z.3
  • 49
    • 0020531293 scopus 로고
    • Desensitization of lh release in cultured pituitary cells by gnrh
    • Keri G, Nikolics K, Teplan I, Molnar J 1983 Desensitization of LH release in cultured pituitary cells by GnRH. Mol Cell Endocrinol 30:109
    • (1983) Mol Cell Endocrinol , vol.30 , pp. 109
    • Keri, G.1    Nikolics, K.2    Teplan, I.3    Molnar, J.4
  • 50
    • 0021275222 scopus 로고    scopus 로고
    • Multiple stimulation of the adenohypophysis by combinations of hypothalamic releasing factors
    • Wehrenberg WB, Baird A, Ying S-Y, Rivier C, Ling N, Guillemin R 1984 Multiple stimulation of the adenohypophysis by combinations of hypothalamic releasing factors. Endocrinology 114: 1995
    • (1984) Endocrinology , vol.114 , pp. 1995
    • Wehrenberg, W.B.1    Baird, A.2    Ying, S.-Y.3    Rivier, C.4    Ling, N.5    Guillemin, R.6
  • 51
    • 0021332344 scopus 로고
    • Biphasic effect of estrogen on gnrh induced lh release in monolayer cultures of rat and monkey pituitary cells
    • Frawley LS, Neill JD 1984 Biphasic effect of estrogen on GnRH induced LH release in monolayer cultures of rat and monkey pituitary cells. Endocrinology 114:659
    • (1984) Endocrinology
    • Frawley, L.S.1    Neill, J.D.2
  • 53
    • 0021277589 scopus 로고    scopus 로고
    • Pituitarygnrhreceptor responses to gnrh in hypothalus-lesioned rats: Inhibition of responses to hyperprolactinemia and evidence that testosterone and estradiol modulate gnrh secretion at postreceptor sites
    • Pieper DR, Gala RR, Schiff MA, Regiani SR, Marshall JC 1984 Pituitary GnRH receptor responses to GnRH in hypothalus-lesioned rats: inhibition of responses to hyperprolactinemia and evidence that testosterone and estradiol modulate GnRH secretion at postreceptor sites. Endocrinology 115:1 190
    • Endocrinology
    • Pieper, D.R.1    Gala, R.2    Schiff, R.3    Regiani, M.4    Marshall, J.C.5
  • 54
    • 0021350519 scopus 로고    scopus 로고
    • Biphasic regulation of the gnrh receptor by receptor microaggregation and intracellular calcium levels
    • Conn PM, Rogers DC, Seay SG 1984 Biphasic regulation of the GnRH receptor by receptor microaggregation and intracellular calcium levels. Mol Pharmacol 25:51
    • Mol Pharmacol
    • Conn, P.M.1    Rogers, D.C.2    Seay, S.G.3
  • 55
    • 0020670752 scopus 로고    scopus 로고
    • Gnrh-mediated desensitization of the pituitary gonadotrope is not calcium dependent
    • Smith WA, Conn PM 1983 GnRH-mediated desensitization of the pituitary gonadotrope is not calcium dependent. Endocrinology 112:408
    • Endocrinology
    • Smith, W.A.1    Conn, P.M.2
  • 56
    • 0021363787 scopus 로고    scopus 로고
    • The self-priming effect of gnrh on lh release: Observations using rat anterior pituitary fragments and dispersed cells continuously perifused in parallel
    • Evans WS, Uskavitch DR, Kaiser DL, Hellmann P, Borges JLC, Thorner MO 1984 The self-priming effect of GnRH on LH release: observations using rat anterior pituitary fragments and dispersed cells continuously perifused in parallel. Endocrinology 114:861
    • Endocrinology
    • Evans, W.S.1    Uskavitch, D.R.2    Kaiser, D.L.3    Hellmann, P.4    Borges, J.5    Thorner, M.O.6
  • 58
    • 0019511376 scopus 로고    scopus 로고
    • Pituitary gnrh receptors: Effects of castration steroid replacement, and the role of gnrh in modulating receptors
    • Frager MS, Pieper DR, Tonetta SA, Duncan JA, Marshall JC 1981 Pituitary GnRH receptors: effects of castration steroid replacement, and the role of GnRH in modulating receptors. J Clin Invest 67:615
    • J Clin Invest
    • Frager, M.S.1    Pieper, D.R.2    Tonetta, S.A.3    Duncan, J.A.4    Marshall, J.C.5
  • 59
    • 0021331316 scopus 로고    scopus 로고
    • Regulation of lh release by pulsatile and continuous administration of gnrh to superfused rat and hamster pituitary cells
    • Baird CJ, Tharandt L, Tamarkin L 1984 Regulation of LH release by pulsatile and continuous administration of GnRH to superfused rat and hamster pituitary cells. Endocrinology 114:1041
    • Endocrinology
    • Baird, C.J.1    Tharandt, L.2    Tamarkin, L.3
  • 60
    • 0021328918 scopus 로고    scopus 로고
    • Gnrh-receptor stimulates gonadotrope desensitization
    • Smith WA, Conn PM 1984 GnRH-receptor stimulates gonadotrope desensitization. Endocrinology 114:553
    • Endocrinology
    • Smith, W.A.1    Conn, P.M.2
  • 61
    • 85003167210 scopus 로고    scopus 로고
    • Gnrh-mediated desensitization of cultured rat anterior pituitary cells can be uncoupled from lh release
    • press
    • Jinnah HA, Conn PM, GnRH-mediated desensitization of cultured rat anterior pituitary cells can be uncoupled from LH release. Endocrinology, in press
    • Endocrinology
    • Jinnah, H.A.1    Conn, P.M.2
  • 62
    • 0019446807 scopus 로고    scopus 로고
    • Photoaffinity labeling of luteinizing hormone releasing hormone receptor of rat pituitary membrane preparations
    • Hazum E 1981 Photoaffinity labeling of luteinizing hormone releasing hormone receptor of rat pituitary membrane preparations. Endocrinology 109:1281
    • Endocrinology
    • Hazum, E.1
  • 63
    • 85003185081 scopus 로고    scopus 로고
    • Radiation inactivation (Target size analysis) of the rat pituitary gnrh receptor
    • Conn PM, Venter C 1984 Radiation inactivation (target size analysis) of the rat pituitary GnRH receptor. Endocrinology 116:1324
    • Endocrinology
    • Conn, P.M.1    Venter, C.2
  • 64
    • 0019294082 scopus 로고    scopus 로고
    • Receptormediated internalization of fluorescent gonadotropin releasing hormone by pituitary gonadotropes
    • Hazum E, Cuatrecasas P, Marian J, Conn PM 1980 Receptormediated internalization of fluorescent gonadotropin releasing hormone by pituitary gonadotropes. Proc Nat Acad Sci USA 77:6692
    • Proc Nat Acad Sci USA
    • Hazum, E.1    Cuatrecasas, P.2    Marian, J.3    Conn, P.M.4
  • 65
    • 0019851317 scopus 로고    scopus 로고
    • Lh release and gnrh-receptor internalization: Independent actions of gnrh
    • Conn PM, Hazum E 1981 LH release and GnRH-receptor internalization: independent actions of GnRH. Endocrinology 109:2040
    • Endocrinology
    • Conn, P.M.1    Hazum, E.2
  • 66
    • 0019454517 scopus 로고    scopus 로고
    • Stimulation of pituitary gonadotropin release does not require internalization of gonadotropin releasing hormone
    • Conn PM, Smith RG, Rogers DC 1981 Stimulation of pituitary gonadotropin release does not require internalization of gonadotropin releasing hormone. J Biol Chem 256:1098
    • J Biol Chem
    • Conn, P.M.1    Smith, R.G.2    Rogers, D.C.3
  • 67
    • 0020521350 scopus 로고    scopus 로고
    • Intracellular pathways of electron opaque gnrh-derivatives bound by cultured gonadotropes
    • Jennes L, Stumpf WE, Conn PM 1983 Intracellular pathways of electron opaque GnRH-derivatives bound by cultured gonadotropes. Endocrinology 113:1683
    • Endocrinology
    • Jennes, L.1    Stumpf, C.2    Conn, W.3
  • 68
    • 0021272675 scopus 로고    scopus 로고
    • Receptor-mediated binding and uptake of gnrh agonist and antagonist in cultured pituitary cells
    • Jennes L, Stumpf WE, Conn PM 1984 Receptor-mediated binding and uptake of GnRH agonist and antagonist in cultured pituitary cells. Peptides 5:215
    • Peptides
    • Jennes, L.1    Stumpf, C.2    Conn, W.3
  • 70
    • 0020328255 scopus 로고    scopus 로고
    • Conversion of a gonadotropin releasing hormone antagonist to an agonist: Implication for a receptor microaggregate as the functional unit for signal transduction
    • Conn PM, Rogers DC, Stewart JM, Neidel J, Sheffield T 1982 Conversion of a gonadotropin releasing hormone antagonist to an agonist: implication for a receptor microaggregate as the functional unit for signal transduction. Nature 296:653
    • Nature
    • Conn, P.M.1    Rogers, D.C.2    Stewart, J.M.3    Neidel, J.4    Sheffield, T.5
  • 71
    • 0020403663 scopus 로고    scopus 로고
    • Gonadotropin releasing hormone stimulation of luteinizing hormone: A ligand-receptor effect model for receptor mediated responses
    • Blum JJ, Conn PM 1982 Gonadotropin releasing hormone stimulation of luteinizing hormone: a ligand-receptor effect model for receptor mediated responses. Proc Natl Acad Sci USA 79:7307
    • Proc Natl Acad Sci USA
    • Blum, J.J.1    Conn, P.M.2
  • 72
    • 0020438571 scopus 로고    scopus 로고
    • Lh release from dissociated pituitary cells by dimerization of occupied lhrh receptors
    • Gregory H, Taylor CL, Hopkins CR 1982 LH release from dissociated pituitary cells by dimerization of occupied LHRH receptors. Nature 300:269
    • Nature
    • Gregory, H.1    Taylor, C.L.2    Hopkins, C.R.3
  • 73
    • 0020162299 scopus 로고    scopus 로고
    • Potency enhancement of a gnrh agonist: Gnrh-receptor microaggregation stimulates gonadotropin release
    • Conn PM, Rogers DC, McNeil R 1982 Potency enhancement of a GnRH agonist: GnRH-receptor microaggregation stimulates gonadotropin release. Endocrinology 111:335
    • Endocrinology
    • Conn, P.M.1    Rogers, D.C.2    McNeil, R.3


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