Prophylactic Efficacy of Intranasal Alpha2-Interferon against Rhinovirus Infections in the Family Setting

New England Journal of Medicine

Volumn 314, Issue 2, 1986, Pages 65-70

  Douglas, Robert M ^a,b   Moore, Brian W ^a,b   Miles, Helen B ^a,b   Davies, Lorraine M ^a,b   Graham, Neil M h ^a,b   Ryan, Philip ^a,b   Worswick, David A ^a,b   Albrecht, Janice K ^a,b  

^a UNIVERSITY OF ADELAIDE   (Australia)

^b MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; ALPHA2 INTERFERON; PLACEBO;

ADVERSE DRUG REACTION; CLINICAL TRIAL; COMMON COLD; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; EPISTAXIS; FAMILY; HUMAN; HUMAN EXPERIMENT; IMMUNOPROPHYLAXIS; INTRANASAL DRUG ADMINISTRATION; NORMAL HUMAN; PREVENTION; PRIORITY JOURNAL; PROPHYLAXIS; RESPIRATORY SYSTEM; RHINOVIRUS;

EID: 0022657144     PISSN: 00284793     EISSN: 15334406     Source Type: Journal    
DOI: 10.1056/NEJM198601093140201     Document Type: Article

References (8)

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2. Phillpotts RJ, Scott GM, Higgins PG, Wallace J, Tyrrell DAJ, Gauci CL. An effective dosage regimen for prophylaxis against rhinovirus infection by intranasal administration HuIFN-α2. Antiviral Res 1983; 3: 121–36.
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7. Gwaltney JM Jr. Rhinoviruses. In: Evans AS, ed. Viral infections of humans: epidemiology and control. 2nd ed. New York: Plenum, 1982:491–517.
8. Protzman WP, Jacobs SL, Minnicozzi M, Oden EM, Kelsey DK. A radioimmunologic technique to screen for antibodies to α-2 interferon. J Immunol Methods 1984; 75: 317–23.