Amodiaquine induced agranulocytosis and liver damage

British Medical Journal (Clinical research ed.)

Volumn 292, Issue 6522, 1986, Pages 721-723

  Neftel, Klaus A ^a   Frick, Paul G ^a   Feh, Jérg ^a   Woodtly, Werner ^b   Schmid, Martin ^c  

^a UNIVERSITY HOSPITAL ZURICH   (Switzerland)

^b Spital Pflegi Neumünster   (Switzerland)

^c City Hospital Zürich   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

AMODIAQUINE; DEXAMETHASONE; FANSIDAR; LIDOCAINE; PHENYLBUTAZONE; PYRIMETHAMINE; SULFADOXINE;

ADOLESCENT; ADULT; AGED; AGRANULOCYTOSIS; ARTICLE; FEMALE; HUMAN; IATROGENIC DISEASE; LIVER; LIVER DISEASE; MALARIA; MALE; NECROSIS; PATHOLOGY; (2 CARBAMOYLPHENOXY)ACETIC ACID; ADVERSE DRUG REACTION; BLOOD AND HEMOPOIETIC SYSTEM; CLINICAL ARTICLE; DIAGNOSIS; DRUG THERAPY; HISTOLOGY; INTOXICATION; LIVER BIOPSY; LIVER INJURY; LIVER NECROSIS; LIVER TOXICITY; NEUTROPENIA; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; THERAPY;

ADOLESCENT; ADULT; AGED; AGRANULOCYTOSIS; AMODIAQUINE; FEMALE; HUMAN; LIVER; LIVER DISEASES; MALARIA; MALE; MIDDLE AGE; NECROSIS;

EID: 0022655075     PISSN: 02670623     EISSN: None     Source Type: Journal    
DOI: 10.1136/bmj.292.6522.721     Document Type: Article

References (19)

1. Love, J, Foulk, R, Williams, RGW, Mitchell, RB. Evaluation of amodiaquine (Camoquin) in the treatment of relapsing vivax malaria. Amf MedSci 1953;225:26–33.
2. Kennedy, AF. Absolute neutrophil Ieucopenia after uncontrolled use of amodiaquine. Br Med f 1955;ii:475–476.
3. Yates, JE, Leeper, RW, Fishler, MC. Blood dyscrasia following Camoquin (amodiaquine). Kaiser Foundation Medical Bulletin 1955;3:192–198.
4. Glick, L. Fatal agranulocytosis during treatment with amodiaquine. BrMedf 1957;i:932.
5. Kersley, GD. Amodiaquine and hydroxychloroquine in rheumatoid arthritis. Lancet 1959;ii: 886–888.
6. Perry, HO, Bartholomew, LG, Hanlon, DG. Nearly fatal reaction to amodiaquine. JAMA 1962;179:598–601.
7. Booth, K, Larkin, K, Maddocks, I. Agranulocytosis coincident with amodiaquine therapy. Br Med f 1967;iii: 32–33.
8. Lind, DE, Levi, JA, Vincent, PC. Amodiaquine-induced agranulocytosis: toxic effect of amodiaquine in bone marrow cultures in vitro. BrMedf 1973;i:458–460.
9. Gillespie, P, Wagner, F. Amodiaquine agranulocytosis. Medf Aust 1977;i:298–299.
10. Lepeu, G, Codine, P, Janbon, F, Bertrand, A. Agranulocytose a I’ amodiaquine. Nouv Presse Med 1981;10:2827–2828.
11. Bepler, CR, Baier, HN, McCracken, S, Rentschler, CL, Rogers, FB, Lansbury, JA 15-month controlled study of the effects of amodiaquine (Camoquin) in rheumatoid arthritis. Arthritis Rheum 1959;2:403–413.
12. Pomeroy, H, Warren, C, Mills, D, Clark, GM. The effect of amodiaquine (Camoquin) on the course of rheumatoid arthritis. Arthritis Rheum 1959;2:396–402.
13. Schulthess, HK, von Felten, A, Gmür, J, Neftel, K. Amodiaquininduzierte Agranulozytose bei Malariaprophylaxe: Nachweis eines Amodiaquin-abhängigen zytotoxischen Antikörpers gegen Granulozyten. Schweiz Med Wochenschr 1983;113:1912–1913.
14. Mackenzie, AH, Scherbel, AL. Chloroquine and hydroxychloroquine in rheumatological therapy. Clin Rheum Dis 1980;6:545–566.
15. Gonasun, LM, Potts, AM. In vitro inhibition of protein synthesis in the retinal pigment epithelium by chloroquine. Investigative Ophthalmology 1974;13:107–115.
16. Tester-Dalderup, CBM. In: Dukes MNG, ed. Meyler’s side effects of drugs. Amsterdam-Oxford-Princeton: Excerpta Medica, 1980:483.
17. Schmid, M, Hefti, ML, Gattiker, R, Kistler, HJ, Senning, A. Benign postoperative intrahepatic cholestasis. N Englf Med 1965;272:545–550.
18. Pichlmayr, I, Stich, W. Der bilirubinostatische Ikterus—eine neue Ikterusform beim Zusammen-treffen von Operation, Nekrose und Bluttransfusion. Klin Wochenschr 1962;40:665–667.
19. Hatton, CSR, Peto, TEA, Bunch, C, et al. Frequency of severe neutropenia associated with amodiaquine prophylaxis against malaria. Lancet 1986;i:411–414.