Differential Effects of Polyadenylation Regions on Gene Expression in Mammalian Cells

DNA

Volumn 5, Issue 2, 1986, Pages 115-122

  Pfarr, David S ^a   Rieser, Lauren A ^a   Woychik, Richard P ^b   Rottman, Fritz M ^b   Rosenberg, Martin ^a   Reff, Mitchell E ^a  

^a Smith Kline & French Laboratories ^*  (United States)

^b CASE WESTERN RESERVE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA;

CELL CULTURE; GENE EXPRESSION; GENETIC ENGINEERING; HEREDITY; IN VITRO STUDY; MAMMAL; MARKER GENE; NONHUMAN; POLYADENYLATION;

ANIMALS; BACTERIAL PROTEINS; CATTLE; CELLS, CULTURED; COLLAGEN; CRICETINAE; DNA, RECOMBINANT; GALACTOKINASE; GENE EXPRESSION REGULATION; GROWTH HORMONE; HUMANS; PENTOSYLTRANSFERASES; PLASMIDS; POLY A; PROMOTER REGIONS (GENETICS); RECOMBINANT PROTEINS; RNA PROCESSING, POST-TRANSCRIPTIONAL; RNA, MESSENGER; SIMIAN VIRUS 40; SPECIES SPECIFICITY;

BOVINAE; MAMMALIA;

EID: 0022651692     PISSN: 01980238     EISSN: 15577430     Source Type: Journal    
DOI: 10.1089/dna.1986.5.115     Document Type: Article

References (20)

1. BERGET, S.M. (1984). Are U4 small nuclear ribonucleoproteins involved in polyadenylation? Nature 309, 179–182.
2. BRAWERMAN, G. (1974). Eukaryotic messenger RNA. Ann. Rev. Biochem. 43, 621–642.
3. FIERS, W., CONTRERAS, R., HAEGEMAN, G., ROGIERS, R., VANDE VOORDE, A., VAN HEUVERSWYN, H., VAN HERREWEGHE, J., VOLCKAERT, G., and YSEBAERT, M. (1978). Complete nucleotide sequence of SV40 DNA. Nature 273, 113–120.
4. FITZGERALD, M., and SHENK, T. (1981). The sequence 5′-AAUAAA-3′ forms part of the recognition site for polyadenylation of late SV40 mRNAs. Cell 24, 251–260.
5. GIL, A., and PROUDFOOT, N.J. (1984). A sequence downstream of AAUAAA is required for rabbit β-globin mRNA 3′-end formation. Nature 312, 473–474.
6. JOHANSEN, H., REFF, M., SCHUMPERLI, D., and ROSENBERG, M. (1984a). Studying eukaryotic transcription and translation by gene fusion. In B.F.C. Clark and H.U. Petersen, Ed. The Alfred Benzon Symposium No. 19. (Munksgaard, Copenhagen) pp. 413–429.
7. JOHANSEN, H., SCHUMPERLI, D., and ROSENBERG, M. (1984b). Affecting gene expression by altering the length and sequence of the 5′ leader. Proc. Natl. Acad. Sci. USA 81, 7698–7702.
8. MANIATIS, T., FRITSCH, E.F., and SAMBROOK, J. (1982). Molecular Cloning: A Laboratory Manual. (Cold Spring Harbor Laboratory, Cold Spring Harbor, New York.)
9. McDEVITT, M.A., IMPERIALE, M.J., ALI, H., and NEVINS, J.R. (1984). Requirement of a downstream sequence for generation of a poly(A) addition site. Cell 37, 993–999.
10. McLAUCHLAN, J., GAFFNEY, D., WHITTON, J.L., and CLEMENTS, J.B. (1985). The consensus sequence YGTGTTYY located downstream from the AATAAA signal is required for efficient formation of mRNA 3′ termini. Nucleic Acids Res. 13, 1347–1368.
11. MYERS, J.C., DICKSON, L.A., DEWET, W., BERNARD, M.P., CHU, M.-L., LIBERTO, M.D., PEPE, G., SANGI-ORGI, F.O., and RAMIREZ, F. (1983). Analysis of the 3′ end of the human pro α 2(1) collagen gene: Utilization of multiple polyadenylation sites in cultured fibroblasts. J. Biol. Chem. 258, 10128–10135.
12. PETERSON, J.L., and McBRIDE, O.W. (1980). Cotransfer of linked eukaryotic genes and efficient transfer of hypoxanthine phosphoribosyl-transferase by DNA-mediated gene transfer. Proc. Natl. Acad. Sci. USA 77, 1583–1587.
13. PFARR, D.S., SATHE, G., and REFF, M.E. (1985). A highly modular cloning vector for the analysis of eukaryotic genes and gene regulatory element. DNA 4, 461–468.
14. PROUDFOOT, N.J., and BROWNLEE, G.G. (1976). 3′ Noncoding region sequences in eukaryotic messenger RNA. Nature 263,211–214.
15. ROSENFELD, M.G., MERMOD, J.J., AMARA, S.G., SWANSON, L.W., SAWCHENKO, P.E., RIVIER, J., VALE, W.W., and EVANS, R.M. (1983). Production of a novel neuropeptide encoded by the calcitonin gene via tissue-specific RNA processing. Nature 304, 129–135.
16. SCHUMPERLI, D., HOWARD, B.H., and ROSENBERG, M. (1982). Efficient expression of Escherichia coli galactokinase gene in mammalian cells. Proc. Natl. Acad. Sci. USA 79, 257–261.
17. SIMONSEN, C.C., and LEVINSON, A.D. (1983). Analysis of processing and polyadenylation signals of the hepatitis B virus surface antigen gene by using simian virus 40-hepatitis B virus chimeric plasmids. Mol. Cell. Biol. 3, 2250–2258.
18. TOSI, M., YOUNG, R.A., HAGENBUCHLE, O., and SCHIBLER, V. (1981). Multiple polyadenylation sites in a mouse α-amylase gene. Nucleic Acids Res. 9, 2313–2323.
19. WIGLER, M., PELLICER, A., SILVERSTEIN, S., AXEL, R., URLAUB, G., and CHASIN, L. (1979). DNA-mediated transfer of the adenine phosphoribosyl-transferase locus into mammalian cells. Proc. Natl. Acad. Sci. USA 76, 1373–1376.
20. WOYCHIK, R.P., LYONS, R.H., POST, L., and ROTTMAN, F.M. (1984). Requirement for the 3′ flanking region of the bovine growth hormone gene for accurate polyadenylation. Proc. Natl. Acad. Sci. USA 81, 3944–3948.