Release of platelet activating factor and its involvement in the first phase of carrageenin-induced rat foot edema

European Journal of Pharmacology

Volumn 120, Issue 1, 1986, Pages 33-41

  Hwang, San Bao ^a   Lam, My Hanh ^a   Li, Chang Ling ^a   Shen, Tsung Ying ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

Carrageenin; PAF; PAF antagonists; Rat hindpaw edema

Indexed keywords

2,5 BIS(3,4,5 TRIMETHOXYPHENYL)TETRAHYDROFURAN; CARRAGEENAN; HISTAMINE; INDOMETACIN; KADSURENONE; THROMBOCYTE ACTIVATING FACTOR;

ANIMAL EXPERIMENT; ANTAGONISM; DRUG EFFICACY; EDEMA; NONHUMAN; PRIORITY JOURNAL; RAT; SUBCUTANEOUS TISSUE; THROMBOCYTE ACTIVATING FACTOR H 3;

ANIMAL; ANTI-INFLAMMATORY AGENTS; BENZOPYRANS; CARRAGEENAN; EDEMA; MALE; PLATELET ACTIVATING FACTOR; RATS; RATS, INBRED STRAINS; TIME FACTORS;

EID: 0022649208     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/0014-2999(86)90636-9     Document Type: Article

References (29)

1. Semisynthese et structure proposee du facteur activant les plaquettes (PAF). PAF acether, un alkyl ether analog de la lyso-phosphatidylcholine
2. Platelet activating factor acether (PAF-acether) involvement in acute inflammatory and pain processes
3. New neolignans from piper futokadsura
4. Mediators of the inflammation induced in the rat paw by carrageenin
5. Platelet-activating factor. Evidence for 1-O-alkyl-2-acetyl-sn-glyceryl-3-phosphorylcholine as the active component (a new class of lipid chemical
6. Studies of the mediators of the acute inflammatory response induced in rats in different sites by carrageenin and turpentine
7. Platelet activating factor (PAF) involvement in endotoxin-induced hypotension in rats. Studies with PAF receptor antagonist kadsurenone
8. A pharmacologic analysis of the action of platelet-activating factor in the induction of hindpaw edema in the rat
9. Principles of radioreceptorassays
10. Therapeutic reduction of ongoing carrageenin induced inflammation by lipoxygenase, but not cyclooxygenase inhibitors
11. A simple method for the quantitative extraction of dye extravasated into the skin
12. Effects of nonsteroid antiinflammatory drugs on the specific binding of platelet activating factor to membrane preparations of rabbit platelets
13. Trans-2,5-bis-(3,4,5-trimethoxyphenyl) tetrahydrofuran: An orally active specific and competitive receptor antagonist of platelet activating factor (PAF)
14. A synthetic competitive and specific antagonist of platelet activating factor
15. Membrane receptors for platelet activating factor (PAF) and a competitive specific PAF-receptor antagonist, kadsurenone
16. Characterization of cutaneous vascular permeability induced by platelet activating factor (PAF) in guinea pigs and rats and its inhibition by a PAF receptor antagonist
17. Specific receptor sites for 1-O-alkyl-2-O-acetyl-sn-glycero-3-phosphocholine (platelet activating factor) on rabbit platelet and guinea pig smooth muscle membranes
18. Quantitative drug assays using radioreceptor techniques
19. Molecular species of platelet activating factor generated by human neutrophils challenged with ionophore A23187
20. PAF-acether: A mediator of inflammation and asthma
21. Immunopharmacology of acetyl glyceryl ether phosphorylcholine (AGEPC)
22. Characterization of a platelet activating factor (PAF) receptor antagonist isolated from haifenteng (piper futokadsura): Specific inhibition of in vitro and in vivo PAF-induced effects
23. Chemical and biochemical aspects of platelet activating factor: A novel class of acetylated ether-linked choline-phospholipids
24. Platelet-activating factor today
25. Biphasic development of carrageenin edema in rats
26. Parallel assay of prostaglandin-like activiti in rat inflammator exudate by means of cascade superfusion
27. Release of histamine, kinin and prostaglandin during carrageenin-induced inflammation in the rat
28. Carrageenin-induced edema in hindpaw of the rat as an assay for antiinflammatory drugs
29. Antiinflammatory and antipyretic activities of indomethacin, 1-(p-chlorobenzoyl)-5-methoxy-methylindole-3-acetic acid