Characterization of Curaremimetic Neurotoxin Binding Sites on Membrane Fractions Derived from the Human Medulloblastoma Clonal Line, TE671

Journal of Neurochemistry

Volumn 46, Issue 6, 1986, Pages 1936-1941

  Lukas, Ronald J ^a  

^a BARROW NEUROLOGICAL INSTITUTE   (United States)

Author keywords

Acetylcholine; Acetylcholine receptor; Anti receptor antibodies; Nicotinic receptor; Bungarotoxin

Indexed keywords

ACETYLCHOLINE; ALCURONIUM; ALPHA BUNGAROTOXIN; ALPHA BUNGAROTOXIN I 125; ATROPINE; BENZOQUINONIUM; BROMOACETYLCHOLINE; CARBACHOL; DECAMETHONIUM; DITHIOTHREITOL; GALLAMINE; HEXAMETHONIUM; LOBELINE; MECAMYLAMINE; MUSCARINE; N ETHYLMALEIMIDE; NEUROTOXIN; NICOTINE; NICOTINIC RECEPTOR; PHYSOSTIGMINE; PILOCARPINE; RADIOISOTOPE; RECEPTOR ANTIBODY; TUBOCURARINE CHLORIDE;

CELL LINE; CENTRAL NERVOUS SYSTEM; DRUG BINDING; DRUG MONITORING; HUMAN; HUMAN CELL; IN VITRO STUDY; MEDULLOBLASTOMA; MEMBRANE BINDING; METHODOLOGY; PERIPHERAL NERVOUS SYSTEM; PRIORITY JOURNAL; RECEPTOR BINDING; TOPICAL DRUG ADMINISTRATION;

ACETYLCHOLINE; BINDING SITES; BINDING, COMPETITIVE; BUNGAROTOXINS; CELL LINE; CLONE CELLS; CURARE; DITHIOTHREITOL; ETHYLMALEIMIDE; HUMAN; KINETICS; MEDULLOBLASTOMA; NICOTINE; RECEPTORS, CHOLINERGIC; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.; TUBOCURARINE;

EID: 0022648957     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.1986.tb08516.x     Document Type: Article

References (26)

1. 3H‐nicotine binding to intact and solubilized rat brain membranes and evidence for its noncholinergic nature
2. Bromoacetylcholine as an affinity label of the acetylcholine receptor from Torpedo californica
3. Anti‐acetylcholine receptor antibodies directed against the α‐bungarotoxin binding site induce a unique form of experimental myasthenia
4. Monoclonal antibodies against purified nicotinic acetylcholine receptor
5. Protein measurement with the Folin phenol reagent
6. Nicotinic acetylcholine receptor‐like antigenic determinants and alpha‐bungarotoxin binding sites in rat brain
7. Properties of curaremimetic neurotoxin binding sites in the rat central nervous sytem
8. Monoclonal rat anti‐Torpedo electroplax nicotinic acetylcholine receptor antibodies; immunochemical characterization
9. Detection of low‐affinity α‐bungarotoxin binding sites in the rat central nervous system
10. Alpha‐bungarotoxin, bromoacetylcholine and anti‐nicotinic cholinergic receptor antibody binding sites on the PC12 pheochromocytoma line
11. Alpha‐bungarotoxin, bromoacetylcholine and anti‐nicotinic acetylcholine receptor antibody binding sites on the human medulloblastoma line, TE671
12. 86rubidium ion efflux studies
13. Functional nicotinic acetylcholine receptors on the clonal line, TE671
14. Interactions of polyclonal anti‐Electrophorus nicotinic receptor antisera with Torpedo nicotinic receptor
15. 2+ on agonist‐specific state transitions of a central nervous system nicotinic acetylcholine receptor
16. Characterization of nicotine binding in mouse brains and comparison with the binding of alpha‐bungarotoxin and quinuclidinyl benzilate
17. Establishment of a human medulloblastoma cell line
18. α‐Bungarotoxin binding sites in the CNS
19. Evidence that certain peripheral anti‐acetylcholine receptor antibodies do not interact with brain BuTX binding sites
20. Autoimmune response to acetylcholine receptor
21. Studies on purified eel acetylcholine receptor and anti‐acetylcholine receptor antibody
22. Stereospecific nicotine receptors on rat brain membranes
23. Nicotinic receptors of the central and autonomic nervous system
24. 3H]acetylcholine in rat brain
25. Effects of morphological differentiation on calcium channels and cholinergic character of TE671 medulloblastoma cells
26. Neuronal‐like features of TE671 cells: presence of a functional nicotinic cholinergic receptor