Characteristics of interaction of the antiandrogen flutamide with the androgen receptor in various target tissues

Molecular and Cellular Endocrinology

Volumn 44, Issue 3, 1986, Pages 261-270

  Simard, J ^a   Luthy, I ^a   Guay, J ^a   Belanger A ^a   Labrie, F ^a  

^a UNIVERSITÉ LAVAL   (Canada)

Author keywords

anterior pituitary gland; non steroidal antiandrogen; prostatic carcinoma; pure antiandrogen; Shionogi mammary carcinoma; uterus

Indexed keywords

ANDROGEN ANTIBODY; FLUTAMIDE; HYDROXYFLUTAMIDE; RADIOISOTOPE; TESTOSTERONE; TESTOSTERONE H 3; UNCLASSIFIED DRUG;

ADENOHYPOPHYSIS; ANIMAL CELL; ARTICLE; DRUG EFFICACY; DRUG INTERACTION; DRUG RECEPTOR BINDING; ENDOCRINE SYSTEM; HORMONE RECEPTOR INTERACTION; HYPOPHYSIS CELL; IN VITRO STUDY; MALE GENITAL SYSTEM; NONHUMAN; PHARMACOKINETICS; PRIORITY JOURNAL; PROSTATE CARCINOMA; RAT;

ANILIDES; ANIMALS; CELLS, CULTURED; FEMALE; FLUTAMIDE; HUMANS; KINETICS; MALE; MAMMARY NEOPLASMS, EXPERIMENTAL; MICE; MICE, INBRED STRAINS; ORGAN SPECIFICITY; PITUITARY GLAND, ANTERIOR; PROSTATE; PROSTATIC NEOPLASMS; RATS; RATS, INBRED STRAINS; RECEPTORS, ANDROGEN; TESTOSTERONE; UTERUS;

EID: 0022639044     PISSN: 03037207     EISSN: None     Source Type: Journal    
DOI: 10.1016/0303-7207(86)90132-2     Document Type: Article

References (39)

1. Time-course of the effect of treatment with a potent LHRH agonist on testicular steroidogenesis and gonadotropin receptor levels in the adult rat
2. Extension of Multiple Range Tests to Group Means with Unequal Numbers of Replications
3. Combination therapy with flutamide and castration (LHRH agonist or orchiectomy) in advanced prostate cancer: a marked improvement in response and survival.
4. Androgen receptors in a Syrian hamster ductus deferens tumour cell line