Protective effects of dithiothreitol on cadmium-induced injury in isolated rat hepatocytes

Toxicology and Applied Pharmacology

Volumn 82, Issue 2, 1986, Pages 225-232

  Stacey, Neill H ^a  

^a UNIVERSITY OF SYDNEY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

CADMIUM; DITHIOTHREITOL;

ANIMAL CELL; CYTOTOXICITY; INTOXICATION; LIVER; LIVER TOXICITY; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMAL; ASPARTATE AMINOTRANSFERASES; CADMIUM; DITHIOTHREITOL; IN VITRO; LIPID PEROXIDES; LIVER; MALE; POTASSIUM; RATS; RATS, INBRED STRAINS; TIME FACTORS;

EID: 0022633042     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/0041-008X(86)90197-3     Document Type: Article

References (24)

1. Regulation of intracellular calcium compartmentation: Studies with isolated hepatocytes and t-butyl hydroperoxide
2. High yield preparation of isolated rat liver parenchymal cells; a biochemical and fine structural study
3. Microsomal lipid peroxidation
4. In vitro assessment of the toxicity of metal compounds
5. New aspects in the biological role of zinc; a stabilizer of marcromolecules and biological membranes
6. Differences in the uptake of cadmium and mercury by rat hepatocyte primary cultures. Role of a sulfhydryl carrier
7. Hepatic uptake of cadmium and its biliary release as affected by dithioerythritol and glutathione
8. Protective effects of vitamin E and dithiothreitol against the hemolysis of rat and goat erythrocytes induced by Tween 20 with or without ascorbic acid and azide
9. Altered permeability of cell membranes
10. Amelioration of mercuric chloride-induced acute renal failure by dithiothreitol
11. Protein measurement with the Folin phenol reagent
12. Influence of paracetamol (acetaminophen) on cadmium-induced lipid peroxidation in hepatocytes from starved rats
13. Different response to liver parenchymal cells from starved and fed rats to cadmium
14. Cadmiuminduced alteration of the energy level in isolated hepatocytes
15. Membrane protein cross-linking is an early step in the pathogenesis of copper-induced hemolytic anemia
16. Factors influencing metabolism and toxicity of metals: a consensus report
17. Cell membrane as site of action of heavy metals
18. Evidence suggesting direct oxidation of human erythrocyte membrane sulfhydryls by copper
19. Effects of thiol agents on the accumulation of cadmium by rat liver parenchymal and Kupffer cells
20. Comparison of the effects of metals on cellular injury and lipid peroxidation in isolated rat hepatocytes
21. Cadmium toxicity and lipid peroxidation in isolated rat hepatocytes
22. Role of sulphydryl groups in T lymphocyte-mediated cytotoxicity
23. Biochemical effects of mercury, cadmium and lead
24. Metabolic targets of metal toxicity