Differential Effect of Subchronic Treatment with Various Neuroleptic Agents on Serotonin2 Receptors in Rat Cerebral Cortex

Journal of Neurochemistry

Volumn 46, Issue 1, 1986, Pages 191-197

  Andree, Terrance H ^a   Mikuni, Masahiko ^a   Tong, Ching Y ^a   Koenig, James I ^a   Meltzer, Herbert Y ^a  

^a UNIVERSITY OF CHICAGO   (United States)

Author keywords

5 HT2) receptors; 5 Hydroxytryptamine (serotonin2; Chlorpromazine; Neuroleptics

Indexed keywords

5,7 DIHYDROXYTRYPTAMINE; ATROPINE; BUTACLAMOL; CHLORPROMAZINE; FLUPENTIXOL; HALOPERIDOL; KETANSERIN H 3; MEPYRAMINE; MOPERONE; NEUROLEPTIC AGENT; PRAZOSIN; PROMETHAZINE; RADIOISOTOPE; SEROTONIN 2 RECEPTOR; SPIPERONE H 3; SULPIRIDE; THIORIDAZINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BRAIN CORTEX; CENTRAL NERVOUS SYSTEM; DRUG INTERACTION; DRUG RECEPTOR BINDING; NERVOUS SYSTEM; NONHUMAN; PHARMACOKINETICS; PRIORITY JOURNAL; RAT; SYNAPTOSOME;

5,7-DIHYDROXYTRYPTAMINE; ANIMALS; ANTIPSYCHOTIC AGENTS; CEREBRAL CORTEX; CHLORPROMAZINE; CLOZAPINE; FEMALE; HALOPERIDOL; IMIPRAMINE; KETANSERIN; LOXAPINE; MALE; PIPERIDINES; RATS; RATS, INBRED STRAINS; RECEPTORS, SEROTONIN; SEROTONIN; SPIPERONE; SULPIRIDE;

ANIMALIA;

EID: 0022632054     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.1986.tb12944.x     Document Type: Article

References (31)

1. Serotonin receptor subsensitivity after acute and chronic treatment with mianserin
2. Acute and chronic effects of serotonin (5‐HT) antagonists on serotonin binding sites
3. 3H]dopamine binding associated with dopamine receptors in calf brain membrane
4. 2 receptor down‐regulation by amitriptyline
5. Catecholamine uptake by synaptosomes in homogenates of rat brain: stereospecificity in different areas
6. 2 receptor changes induced by amitriptyline and desmethylimipramine
7. Stereospecificity of interaction of neuroleptic drugs with neurotransmitters and correlation with clinical potency
8. Stereospecificity and clinical potency of neuroleptics
9. Histamine receptors in brain
10. 2‐serotonergic receptors
11. Serotonergic innervation of the lateral hypothalamus: evidence from synaptosomal uptake studies
12. 1‐receptors in guinea pig brain
13. Brain histamine receptors as targets for antidepressant drugs
14. 2) receptor numbers in the rat brain
15. 3H‐ligand binding sites in vitro
16. 2 receptor binding sites. Binding properties, brain distribution, and functional role
17. Protein measurement with Folin phenol reagent
18. Reduction of serotonin‐2 receptors in rat cerebral cortex after subchronic administration of imipramine, chlorpromazine and the combination thereof
19. Correlations between different measures of anti‐serotonin activity of drugs
20. Long term antidepressant treatment decreases spiroperidol‐labeled serotonin receptor binding
21. Relationship of neuroleptic drug effects at brain dopamine, serotonin, α‐adrenergic, and histamine receptors to clinical potency
22. 2 receptors
23. The newer antidepressants: Structures, pharmacokinetics, pharmacodynamics, and proposed mechanism of action
24. Neuroleptic affinities for human brain receptors and their use in predicting adverse effects
25. Antagonism by antidepressants of neurotransmitter receptors of normal human brain in vitro
26. Major tranquilizers used as antidepressants
27. 3H‐spiperone‐labelled serotonin receptors in the frontal cortex of the rat
28. 3H‐Mepyramine binding in various regions of rat brain following chronic treatment with different classes of antidepressant drugs
29. 2‐receptor antagonism and antidepressant action
30. A controlled comparison of flupenthixol and amitriptyline in depressed outpatients