Efficacy of primidone in essential tremor

Neurology

Volumn 36, Issue 1, 1986, Pages 121-124

  Koller, William C ^a   Royse, Vicki L ^b  

^a LOYOLA UNIVERSITY CHICAGO   (United States)

^b RUSH UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PHENOBARBITAL; PLACEBO; PRIMIDONE; PROPRANOLOL;

ADVERSE DRUG REACTION; ATAXIA; CASE REPORT; CENTRAL NERVOUS SYSTEM; CLINICAL TRIAL; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG COMPARISON; DRUG DOSE; DRUG EFFICACY; DRUG THERAPY; ESSENTIAL TREMOR; HUMAN; INTOXICATION; MAJOR CLINICAL STUDY; MENTAL DISEASE; NERVOUS SYSTEM; NEUROTOXICITY; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; SEDATION; THERAPY; TREMOR; VERTIGO;

DOSE-RESPONSE RELATIONSHIP, DRUG; HUMAN; MALE; MIDDLE AGE; PHENOBARBITAL; PRIMIDONE; PROPRANOLOL; SUPPORT, U.S. GOV'T, NON-P.H.S.; TREMOR;

EID: 0022631856     PISSN: 00283878     EISSN: 1526632X     Source Type: Journal    
DOI: 10.1212/wnl.36.1.121     Document Type: Article

References (15)

1. Larsen TA, Calne DB. Essential tremor. Clin Neuropharmacol 1983;6:198-206.
2. Koller WC. The diagnosis and treatment of tremors. Neurol Clin 1984;2:499-515.
3. Calzetti S, Findley LJ, Perulla E. The response of essential tremor to propranolol: evaluation of clinical variables governing its efficacy on prolonged administration. J Neurol Neurosurg Psychiatry 1983;46:393-8.
4. Teravainen H, Fogelholm R, Larson A. Effect of propranolol on essential tremor. Neurology (Minneap) 1976;26:27-30.
5. O’Brien MD, Upton AR, Toseland PA. Benign familial tremor treated with primidone. Br Med J 1981;282:178-80.
6. Findley LJ, Calzetti S. Double-blind controlled study of primidone in essential tremors: preliminary results. Br Med J 1982;285:608.
7. Koller WC, Royse VL. Time course of a single oral dose of propranolol in essential tremor. Neurology (Cleveland) 1985;35:1494-8.
8. Chakrabarti A, Pearce JMS. Essential tremor: response to primidone. J Neurol Neurosurg Psychiatry 1981;44:600.
9. Koller WC, Biary N. Effect of alcohol on tremors: comparison with propranolol. Neurology (Cleveland) 1984;34:221-2.
10. Gallagher BB, Baumel IP, Mattson RH. Metabolic disposition of primidone and its metabolites in epileptic subjects after single and repeated administration. Neurology (Minneap) 1972;22:1186-92.
11. Woodbury DM, Pippenger CE. Primidone mechanisms of action. In: Woodbury DM, Penry K, Pippenger CE, eds. Antiepileptic drugs. New York: Raven Press, 1982:449-52.
12. Calzetti S, Findley LJ, Pisani F, Richens A. Phenylethyl-malonamide in essential tremor: a double blind controlled study. J Neurol Neurosurg Psychiatry 1981;44:932-4.
13. Baruzzi A, Procacianti G, Martineli P, et al. Phenobarbital and propranolol in essential tremor: a double blind controlled clinical trial. Neurology (Cleveland) 1983;33:296-300.
14. Koller WC. Dose-response relationship of propranolol in essential tremor. Arch Neurol (in press).
15. Koller WC. Long-acting propranolol in essential tremor. Neurology (Cleveland) 1985;35:108-10.