Human duodenal mucosal bicarbonate secretion. Evidence for basal secretion and stimulation by hydrochloric acid and a synthetic prostaglandin E1 analogue

Gastroenterology

Volumn 91, Issue 2, 1986, Pages 370-378

  Isenberg, Jon I ^a   Hogan, Daniel L ^a   Koss, Michael A ^a   Selling, John A ^a  

^a UCSD MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BICARBONATE; CIMETIDINE; HYDROCHLORIC ACID; MISOPROSTOL; PROSTAGLANDIN E1; RADIOISOTOPE;

ACIDIFICATION; BICARBONATE RELEASE; DRUG COMPARISON; DRUG EFFICACY; DRUG INTERACTION; DRUG MECHANISM; DUODENUM; DUODENUM MUCOSA; DUODENUM SECRETION; HUMAN; HUMAN EXPERIMENT; MACROGOL C 14; NORMAL HUMAN; PRELIMINARY COMMUNICATION; PRIORITY JOURNAL; SMALL INTESTINE; TOPICAL DRUG ADMINISTRATION;

ADULT; ALPROSTADIL; BICARBONATES; CIMETIDINE; DUODENUM; FLUOROSCOPY; HUMAN; HYDROCHLORIC ACID; HYDROGEN-ION CONCENTRATION; INTESTINAL MUCOSA; INTUBATION, GASTROINTESTINAL; MIDDLE AGE; MISOPROSTOL; SUPPORT, U.S. GOV'T, P.H.S.; TIME FACTORS;

EID: 0022627980     PISSN: 00165085     EISSN: None     Source Type: Journal    
DOI: 10.1016/0016-5085(86)90571-8     Document Type: Article

References (40)

1. Gastric secretion of bicarbonate
2. Ion transport across isolated antral mucosa of the rabbit
3. − transport by mammalian duodenum in vivo
4. 2
5. Vagal stimulation of human gastric bicarbonate secretion
6. Gastroduodenal alkaline response to acid and taurocholate in conscious dogs
7. Demonstration of a pH gradient at the luminal surface of rat duodenum in vivo and its dependence on mucosal alkaline secretion
8. Secretin, VIP, and PHI stimulate rat proximal duodenal surface epithelial bicarbonate secretion in vivo
9. 2, and inhibition of endogenous prostaglandin synthesis on proximal duodenal bicarbonate secretion in unanesthetized rat
10. Gastroduodenal defense mechanisms
11. − transport isolated proximal bullfrog duodenum by prostaglandins
12. Use of pentagastrin in a test of gastric acid secretion
13. A new method for quantitation of ion fluxes across the in vivo human gastric mucosa
14. New clinical method for measuring the rate of gastric emptying: the double sampling test meal
15. Non-labeled V B12 as a dilution indicator in GI research
16. Distribution and fate of pancreatic enzymes in small intestine of the rat
17. Surgical anatomy of the pancreatic ductal system
18. Calibre and appearance of the pancreatic ducts and relevant clinical problems. A roentgenographic and anatomical study
19. On the excretory ducts of the pancreas in man, with special reference to their relations to each other, to the common bile duct and to the duodenum. A radiological and anatomical study
20. A study of the pancreatic duct system in man by the use of vinyl acetate casts of postmortem preparations
21. Experimental analysis of hydrogen ion diffusion in gastrointestinal mucus glycoprotein
22. Comparison of synthetic and natural porcine secretins on human pancreatic secretion
23. Bicarbonate and cyclic AMP content of pure human pancreatic juice in response to graded doses of synthetic secretin
24. Measurement of gastric functions during digestion of ordinary solid meals in man
25. The acid reducing mechanisms of the normal human duodenum and an observation on duodenal ulcer
26. Acid loss in human duodenum
27. Acid loss in human duodenum: mucosal contribution to neutralization (abstr)
28. Mechanisms of acid disposal in canine duodenum
29. A quantitative statement of the two-component hypothesis of gastric secretion
30. − transport by luminal acid in the frog in vitro
31. Release of VIP, secretin and motilin after duodenal acidification in man
32. +) and indomethacin (I) (abstr)
33. Human proximal versus distal duodenal bicarbonate secretion: effect of endogenous prostaglandin synthesis (abstr)
34. − secretion in response to sham feeding in humans
35. 2 in man
36. 2 on duodenal ulcer healing
37. − fluxes
38. 2 analogs given orally on pancreatic response to secretin in man