Increased Synthesis of Systemic Prostacyclin in Cirrhotic Patients

Gastroenterology

Volumn 90, Issue 3, 1986, Pages 687-694

  Guarner, F ^a,b,c   Guarner, C ^a,b,c   Prieto, J ^a,b,c   Colina, I ^a,b,c   Quiroga, J ^a,b,c   Casas, J ^a,b,c   Freixa, R ^a,b,c   Rosello, J ^a,b,c   Gelpi, E ^a,b,c   Balanzo, J ^a,b,c  

^a UNIVERSITY OF NAVARRA   (Spain)

^b HOSPITAL DE LA SANTA CREU I SANT PAU   (Spain)

^c Instituto de Qufmica Bio Organica ^*  (Spain)

Author keywords

2,3 dinor 6 keto prostaglandin F1 ; 6 keto PGF1 ; 6 keto prostaglandin F11 ; high performance liquid chromatography; HPLC; PGI M; plasma renin activity; PRA

Indexed keywords

6 OXOPROSTAGLANDIN F1 ALPHA; ALDOSTERONE; PROSTACYCLIN; SULINDAC;

ASCITES; CLINICAL ARTICLE; DRUG EFFICACY; DRUG THERAPY; HUMAN; KIDNEY; KIDNEY FAILURE; LIVER; LIVER CIRRHOSIS; ORAL DRUG ADMINISTRATION; PLASMA RENIN ACTIVITY; PRIORITY JOURNAL; THERAPY;

EID: 0022622604     PISSN: 00165085     EISSN: None     Source Type: Journal    
DOI: 10.1016/0016-5085(86)91124-8     Document Type: Article

References (50)

1. Cardiac output at rest in Laennec's cirrhosis
2. Circulatory changes in chronic liver disease
3. General and regional circulatory alterations in cirrhosis of the liver
4. Plasma volume in cirrhosis of the liver. Its relation to portal hypertension, ascites and renal failure
5. Effect of angiotensin-II blockade on systemic and hepatic haemodynamics and on the renin-angiotensin-aldosterone system in cirrhosis with ascites
6. Hepatic and systemic hemodynamics and the renin-angiotensin-aldosterone system in cirrhosis
7. Circulation times in the splanchnic and hepatic beds in alcoholic liver disease
8. Quantitativn of portasystemic shunting from the splenic and mesenteric beds in alcoholic liver disease
9. Morphology of gastric microcirculation in cirrhosis
10. Prolonged infusions of angiotensin II and norepinephrine and blood pressure, electrolyte balance, and aldosterone and cortisol secretion in normal man and in cirrhosis with ascites
11. Effect of blockade of angiotensin II on blood pressure, renin and aldosterone in cirrhosis
12. Characterization of the renin-aldosterone system in decompensated cirrhosis
13. Potential role of increased sympathetic activity in impaired sodium and water excretion in cirrhosis
14. Renin, angiotensin II and juxtaglomerular apparatus in liver cirrhosis
15. Prostaglandins in severe congestive heart failure. Relation to activation of the renin-angiotensin system and hyponatremia
16. Prostaglandins in liver disease
17. Effect of indomethacin and prostaglandin A1 on renal function and plasma renin activity in alcoholic liver disease
18. Prostaglandins: modulators of renal function and pressor resistance in chronic liver disease
19. Sympathetic nervous activity, renin-angiotensin system and renal excretion of prostaglandin E2 in cirrhosis. Relationship to functional renal failure and sodium and water excretion
20. An enzyme isolated from arteries transforms prostaglandin endoperoxides to an unstable substance that inhibits platelet aggregation
21. Effects of nerve stimulation and of administration of noradrenaline or potassium chloride upon the release of prostaglandins 12, E2 and F2a from the perfused mesenteric arterial bed of the rabbit
22. Role of prostacyclin in blood pressure regulation and aldosterone production in conscious rabbits
23. Metabolism of prostacyclin and 6-keto-prostaglandin Fl,,, in man
24. Quantitative analysis of two dinor urinary metabolites of prostaglandin 12
25. Frusemide increases urine 6-keto-PGF1a. Relation to natriuresis, vasodilatation and renin release
26. Analysis of prostacyclin and thromboxane biosynthesis in cardiovascular disease
27. Estimated rate of prostacyclin secretion into the circulation of normal man
28. Systemic prostaglandin 12 synthesis is normal in patients with Bartter's syndrome
29. Metabolic disposition of prostacyclin in humans
30. Endogenous prostacyclin synthesis is decreased during activation of the renin angiotensin system in man
31. Aminoglycoside nephrotoxicity in cirrhosis. Value of 02-microglobulin to discriminate functional renal failure from acute tubular damage
32. Rapid extraction of oxygenated metabolites of arachidonic acid from biologic samples using octadecylsilyl silica
33. Characterization of antibody to prostaglandin F2a
34. Intracerebroventricular infusion of sodium chloride-rich artificial cerebrospinal fluid in rats induces natriuresis and releases an inhibitor of prostaglandin synthesis
35. Increased prostacyclin biosynthesis in patients with severe atherosclerosis and platelet activation
36. Microsomal prostaglandin biosynthesis of human kidney
37. Effects of sulindac and ibuprofen in patients with chronic glomerular disease: evidence for the dependence of renal function on prostacyclin
38. Relevance of urinary 6-keto-prostaglandin Fl,, determination
39. Deranged sodium homeostasis in cirrhosis
40. Disturbed volume homeostasis in patients with cirrhosis of the liver
41. Effects of prostaglandin inhibition on systemic and hepatic hemodynamics in patients with cirrhosis of the liver
42. Hyperdynamic circulation in portal-hypertensioe rat model: a primary factor for maintenance of chronic portal hypertension
43. The relationship between prostacyclin activity and pressure in the portal vein
44. Prostacyclin-like activity in experimental portal hypertension in dogs (abstr)
45. Effects of prostacyclin on hepatic vasculature and metabolism of renin in conscious dogs
46. Prostacyclin increases portal venous flow
47. Renin-angiotensin-aldosterone system in cirrhosis
48. Renal failure in the patient with cirrhosis. The role of active vasoconstriction
49. Renal effects of head-out water immersion in man: implication for an understanding of volume homeostasis
50. Characterization of renal prostaglandin E2 responsiveness in decompensated cirrhosis: implication for renal sodium handling