The effect of antiseptics and topical antimicrobials on wound healing

Journal of Antimicrobial Chemotherapy

Volumn 17, Issue 2, 1986, Pages 135-137

  Leaper, David J ^a   Simpson, Rosemary A ^a  

^a BRISTOL ROYAL INFIRMARY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT; CHLORHEXIDINE; DISINFECTANT AGENT; HYPOCHLOROUS ACID; POVIDONE IODINE; SILVER NITRATE; SULFADIAZINE SILVER; TOPICAL AGENT;

DRUG EFFICACY; EDITORIAL; FIBROBLAST; HUMAN; PRIORITY JOURNAL; SUBCUTANEOUS TISSUE; THERAPY; TOPICAL DRUG ADMINISTRATION; WOUND HEALING;

ANTI-INFECTIVE AGENTS, LOCAL; HUMAN; WOUND HEALING; WOUND INFECTION;

EID: 0022609110     PISSN: 03057453     EISSN: None     Source Type: Journal    
DOI: 10.1093/jac/17.2.135     Document Type: Article

References (24)

1. Alper, J. C., Welch, E. A., Ginsberg, M., Bogaars, H. & Maguire, P. (1983). Moist healing under a vapour permeablemembrane. Journal of American Academy of Dermatology, 8, 347-53.
2. Alvarez, O. M., Mertz, P. M. & Eaglstein, W. H. (1983). The effect of occlusive dressings on collagen synthesis and re-epithelialisation in superficial wounds. Journal of Surgical Research 35, 142-8.
3. Brennan, S. S., Foster, M. E. & Leaper, D. J. (1984). A study of microangiogegenesis in wounds healing by secondary intention. Microcirculation Endothelium and Lymphatics 1, 657-69.
4. Brennan, S. S., Foster, M. E. & Leaper, D. J. (1986). Antiseptics toxicity in wounds healing by secondary intention. Journal of Hospital Infection (in press)
5. Brennan, S. S. & Leaper, D. J. (1985). The effect of antiseptics on the healing wound: a study using the rabbit ear chamber. British Journal of Surgery 72, 780-2.
6. Buchan, I. A., Andrews, J. D. & Lang, S. M. (1981). Laboratory investigation of the composition and properties of pig skin wound exudate under op-site. Bum 8, 39-46.
7. Burke, J. F. (1971). Effects of inflammation on wound repair. Journal of Dental Research 50, 296-301.
8. Butler, W. H. & Iswaran, T. J. (1980). Qhlorhexidine: Safety evaluation. In Problems in the Control of Hospital Infection. Royal Society of Medicine. International Congress and Symposium Series No. 23,45-8.
9. Carrel, A. & Hartman, A. (1916). Cicatrization of Wounds I. The relation between the size of the wound and the rate of its cicatrization. Journal of Experimental Medicine 24,429-45.
10. Fleming, A. (1919). The action of chemical and physiological antiseptics in a septic wound. British Journal of Surgery 7,99-129.
11. Forrest, R. D. (1982a). Early history of wound treatment Journal of the Royal Society of Medicine 75, 198-205.
12. Forrest, R. D. (1982b). Development of wound therapy from the dark ages to the present. Journal of Royal Society of Medicine 75,268-73.
13. Hohn, D. C., Ponce, B., Burton, R. W. & Hunt, T. K. (1977). Antimicrobial systems of the surgical wound. American Journal of Surgery 133, 597-603.
14. Leaper, D. J. & Brennan, S. S. (1986). Lets have a re-think about the use of antiseptics for venous ulcers. Proceedings: Union Internationale de Phlebologie. John Libbey, (in press).
15. Leaper, D. J., Brennan, S. S., Simpson, R. A. & Foster, M. E., (1984). Experimental infection and hydrogel dressings. Journal of Hospital Infections 5, 69-73.
16. Lindhe, J., Hams, S. E., Loe, H. & Rindom Schiott, C. (1979). Influence of topical application of chlorhexidine on chronic gingivitis and gingival wound healing in the dog. Scandinavian Journal of Dental Research 78,471-8.
17. Lister, J. (1867). On the antiseptic principle in the practice of surgery. British Medical Journal 2. 246-48.
18. Lowbury, EJ.L., Miller, R. W. S., Cason, J. S. & Jackson, D. M. (1962). Local prophylactic chemotherapy for burns treatment with tulle gras and the exposure method. Lancet 2, 958-63.
19. Ninneman, J. L. & Stein, M. D. (1981). Suppressor cell induction by povidone iodine: In vitro demonstration of a consequence of clinical bum treatment with Betadine. Journal of Immunology 126, 1905-8.
20. Platt, E. J. L., Babb, J. R., Bridges, K. & Jackson, D. M. (1976). Topical chemoprophylaxis with silver sulphadiazine and silver nitrate chlorhexidine cream: emergence of sulphonamide-resistant gram negative bacilli. British Medical Journal i, 493-6.
21. Platt, J. & Bucknall, R. A. (1984). An experimental evaluation of antiseptic wound irrigation. Journal of Hospital Infection 5,181-8.
22. Skog, E., Araesjo, B., Troeng, T. & Gjores, J. E. (1983). A randomised trial comparing cadexomer iodine and standard treatment in the out-patient management of chronic venous ulcers. British Journal of Dermatology 109, 77-83.
23. Van den Broek, P. J., Buys, L. F. M. & van Furth, R. (1982). Interaction of povidone iodine compounds, phagocytic cells and microorganisms. Antimicrobial Agents and Chemotherapy 22, 593-87.
24. Winter, G. D. (1972). Epidermal regeneration studies in the domestic pig. In Epidermal Wound Healing (Maibach, H. I. & Revere, D. T., Eds.) Year Book Medical Publishers, Chicago & London