Mechanism of thrombin-induced endothelium-dependent coronary vasodilation in dogs: Role of its proteolytic enzymatic activity

Journal of Cardiovascular Pharmacology

Volumn 8, Issue 1, 1986, Pages 29-36

  Ku, David D ^a  

^a UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

Author keywords

Coronary vasodilation; Dogs; Endothelial cells; Endothelium dependent; Proteolytic enzymes; Thrombin; Trypsin

Indexed keywords

ACETYLCHOLINE; ADENOSINE; ADENOSINE TRIPHOSPHATE; ANTITHROMBIN III; APROTININ; CHYMOTRYPSIN; DEXTRO PHENYLALANYLPROLYLARGINYL CHLOROMETHYL KETONE; HEPARIN; HEPARINOID; HIRUDIN; PEPSIN A; PROSTAGLANDIN F2 ALPHA; PROTEINASE; SOYBEAN TRYPSIN INHIBITOR; THROMBIN; TRYPSIN;

ACETYLCHOLINE IODIDE; ANIMAL CELL; ARTERY ENDOTHELIUM; CARDIOVASCULAR SYSTEM; CORONARY ARTERY DILATATION; DOG; DOSE RESPONSE; DRUG COMPARISON; DRUG EFFICACY; DRUG INTERACTION; DRUG POTENTIATION; DRUG RESPONSE; ENDOTHELIUM; HEART; METHODOLOGY; NONHUMAN; PERIPHERAL VASCULAR SYSTEM; PRIORITY JOURNAL; TOPICAL DRUG ADMINISTRATION; TOSYLGLYCYLPROLYLARGININE 4 NITROANILIDE;

AMINO ACID CHLOROMETHYL KETONES; ANIMAL; CORONARY VESSELS; DOGS; ENDOTHELIUM; IN VITRO; MALE; PEPTIDE HYDROLASES; RECEPTORS, CELL SURFACE; RECEPTORS, THROMBIN; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.; THROMBIN; TRYPSIN; VASODILATION;

EID: 0022600508     PISSN: 01602446     EISSN: 15334023     Source Type: Journal    
DOI: 10.1097/00005344-198601000-00005     Document Type: Article

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