Affinity-purified human Interleukin I is cytotoxic to isolated islets of Langerhans

Diabetologia

Volumn 29, Issue 1, 1986, Pages 63-67

  Mandrup Poulsen, T ^a   Bendtzen, K ^b   Nerup, J ^a   Dinarello, C A ^c   Svenson, M ^b   Nielsen, J H ^d  

^a STENO DIABETES CENTER   (Denmark)

^b Rigshospitalet   (Denmark)

^c TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d HAGEDORN RESEARCH INSTITUTE   (Denmark)

Author keywords

Autoimmunity; cytotoxicity; Interleukin 1; lymphokines; macrophages; pancreatic B cells; pancreatic islets pathogenesis; Type 1 (insulin dependent) diabetes mellitus

Indexed keywords

INSULIN; INTERLEUKIN 1; LYMPHOKINE;

ANIMAL CELL; AUTOIMMUNITY; BLOOD AND HEMOPOIETIC SYSTEM; CELLULAR IMMUNITY; CYTOTOXICITY; DRUG EFFICACY; ENDOCRINE SYSTEM; HUMAN; INSULIN DEPENDENT DIABETES MELLITUS; MACROPHAGE; NONHUMAN; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; RAT;

ANIMALS; GLUCAGON; HUMANS; INSULIN; INTERLEUKIN-1; ISLETS OF LANGERHANS; MALE; RATS; RATS, INBRED STRAINS;

EID: 0022596377     PISSN: 0012186X     EISSN: 14320428     Source Type: Journal    
DOI: 10.1007/BF02427283     Document Type: Article

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