Down regulation of serotonin-S2 receptor sites in rat brain by chronic treatment with the serotonin-S2 antagonists: ritanserin and setoperone

Psychopharmacology

Volumn 88, Issue 4, 1986, Pages 434-444

  Leysen, J E ^a   Van Gompel, P ^a   Gommeren, W ^a   Woestenborghs, R ^a   Janssen, P A J ^a  

^a Janssen Pharmaceutica ^*  (Belgium)

Author keywords

Chronic drug treatment; Radioligand binding; Receptor down regulation; Ritanserin; Serotonin antagonist; Serotonin S2 receptors; Setoperone

Indexed keywords

2 [2 (2,6 DIMETHOXYPHENOXY)ETHYLAMINOMETHYL] 1,4 BENZODIOXANE H 3; 2 [[2 (2,6 DIMETHOXYPHENOXY)ETHYL]AMINOMETHYL] 1,4 BENZODIOXAN; ALPRENOLOL; ASTEMIZOLE; BUTACLAMOL; CLOMIPRAMINE; CLONIDINE; CLONIDINE H 3; DESIPRAMINE; DIHYDROALPRENOLOL; DIHYDROALPRENOLOL H 3; DOMPERIDONE; HALOPERIDOL; KETANSERIN; KETANSERIN H 3; LYSERGIDE; MEPYRAMINE; MEPYRAMINE H 3; METHYSERGIDE; NEUROTRANSMITTER; NORADRENALIN; NORADRENALIN H 3; R 51417; R 56724; RADIOISOTOPE; RITANSERIN; SEROTONIN; SEROTONIN 2 ANTAGONIST; SEROTONIN 2 RECEPTOR; SEROTONIN H 3; SETOPERONE; SPIPERONE; SPIPERONE H 3; SUBSTANCE P; SUBSTANCE P H 3; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; BRAIN; CENTRAL NERVOUS SYSTEM; DRUG EFFICACY; DRUG INTERACTION; DRUG RECEPTOR BINDING; NONHUMAN; ORAL DRUG ADMINISTRATION; PHARMACOKINETICS; PRIORITY JOURNAL; RADIOASSAY; RAT; RECEPTOR DOWN REGULATION;

ANIMALS; BRAIN; CORPUS STRIATUM; FRONTAL LOBE; KETANSERIN; MALE; PIPERIDINES; PYRIMIDINONES; RATS; RATS, INBRED STRAINS; RECEPTORS, DOPAMINE; RECEPTORS, DOPAMINE D2; RECEPTORS, NEUROTRANSMITTER; RECEPTORS, SEROTONIN; RITANSERIN;

EID: 0022595471     PISSN: 00333158     EISSN: 14322072     Source Type: Journal    
DOI: 10.1007/BF00178504     Document Type: Article

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