Dendritic cells with antigen-presenting capability reside in airway epithelium, lung parenchyma, and visceral pleura

Journal of Experimental Medicine

Volumn 163, Issue 2, 1986, Pages 436-451

  Sertl, Kaspar ^a,d   Takemura, Tamiko ^c   Tschachler, Erwin ^e   Ferrans, Victor J ^c   Kaliner, Michael A ^a   Shevach, Ethan M ^b  

^a Laboratory of Clinical Investigation   (United States)

^b NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^c NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

^d V Department of Internal Medicine   (Austria)

^e UNIVERSITY OF VIENNA   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENT RECEPTOR; ESTERASE; FC RECEPTOR; HLA DR ANTIGEN;

ANIMAL CELL; ANTIGEN PRESENTATION; DENDRITIC CELL; HUMAN; HUMAN CELL; IMMUNE RESPONSE; LUNG; MOUSE; PLEURA; PRIORITY JOURNAL; RESPIRATORY EPITHELIUM; RESPIRATORY SYSTEM;

ANIMALS; ANTIGEN-PRESENTING CELLS; ANTIGENS, SURFACE; BRONCHI; EPITHELIAL CELLS; FLUORESCENT ANTIBODY TECHNIQUE; HISTOCOMPATIBILITY ANTIGENS CLASS II; HLA-DR ANTIGENS; HUMANS; IMMUNOENZYME TECHNIQUES; LUNG; LYMPHOID TISSUE; MICE; PLEURA; RECEPTORS, IMMUNOLOGIC; RESPIRATORY SYSTEM; TRACHEA;

EID: 0022577256     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.163.2.436     Document Type: Article

References (37)

1. Steinman, R. M., and M. C. Nussenzweig. 1980. Dendritic cells: features and functions. Immunol. Rev. 53:127.
2. Unanue, E. R., D. I. Beller, Ch. Y. Lu, and P. M. Allen. 1984. Antigen presentation: comments on its regulation and mechanism. J. Immunol. 132:1.
3. Stingl, G., S. I. Katz, E. M. Shevach, A. S. Rosenthal, and I. Green. 1978. Analogous functions of macrophages and Langerhans cells in the initiation of the immune response. J. Invest. Dermatol. 71:59.
4. Ashwell, J. D., A. L. DeFranco, W. E. Paul, and R. H. Schwartz. 1985. Can resting B cells present antigen to T cells? Fed. Proc. 44:2475.
5. Nunez, G., E. J. Ball, and P. Stastny. 1983. Accessory cell function of human endothelial cells. I. A subpopulation of la-positive cells is required for antigen presentation. J. Immunol. 131:666.
6. Hirschberg, H., H. Scott, and E. Thorsby. 1981. Human endothelial cells can present antigen to sensitized T lymphocytes in vitro. Transplant. Proc. 13:100.
7. Norcross, M. A., D. M. Bentley, D. H. Margulies, and R. N. Germain. 1984. Membrane la expression and antigen-presenting accessory cell function of L cells transfected with class II major histocompatibility complex genes. . J Exp. Med. 160:1316.
8. Natali, P. G., D. DeMartino, V. Quaranta, M. R. Nicotra, F. Frezza, M. A. Pellegrino, and S. Ferrone. 1981. Expression of la-like antigens in normal human nonlymphoid tissues. Transplantation (Baltimore). 31:75.
9. Toews, G. B., W. C. Vial, M. M. Dunn, P. Guzetta, G. Nunez, P. Stastny, and M. F. Lipscomb. 1984. The accessory cell function of human alveolar macrophages in specific T cell proliferation. J Immunol. 132:181.
10. Ansfield, M. J., H. B. Kaltreider, J. L. Caldwell, and F. N. Herskowitz. 1979. Hyporesponsiveness of canine bronchoalveolar lymphocytes to mitogens: Inhibition of lymphocyte proliferation by alveolar macrophages. J Immunol. 122:542.
11. Schuyler, M. R., and L. S. Todd. 1981. Accessory cell function of rabbit alveolar macrophages. Am. Rev. Respir. Dis. 123:53.
12. Lyons, C. R., and M. F. Lipscomb. 1983. Alveolar macrophages in pulmonary immune responses. I. Role in the initiation of primary immune responses and in the selective recruitment of T-lymphocytes to the lung. J Immunol. 130:1113.
13. Holt, P. G. 1979. Alveolar macrophages. II. Inhibition of lymphocyte proliferation by purified macrophages from rat lung. Immunology 37:429.
14. Weinberg, D. S., and E. R. Unanue. 1981. Antigen-presenting function of alveolar macrophages: uptake and presentation of Listeria monocytogenes. . J Immunol. 126:794.
15. Tandler, B., J. Sherman, and T. F. Boat. 1981. EDTA-mediated separation of cat tracheal lining epithelium. Am. Rev. Respir. Dis. 124:469.
16. Bhattacharya, A., M. E. Dorf, and T. A. Springer. 1981. A shared alloantigenic determinant on la antigens encoded by the I-A I-E subregions: evidence for I region gene duplication. J Immunol. 127:2488.
17. Springer, T. A., G. Galfre, D. S. Secher, and C. Milstein. 1978. Monoclonal xenogeneic antibodies to murine cell surface antigens: identification of novel leucocyte differentiation antigens. Eur. J. Immunol. 8:539.
18. Springer, T. A., G. Galfre, D. S. Secher, and C. Milstein. 1979. Mac-1: a macrophage differentiation antigen identified by monoclonal antibody. Eur. J. Immunol. 9:301.
19. Unkeless, J. C. 1979. Characterization of a monoclonal antibody directed against mouse macrophage and lymphocyte Fc receptors. J. Exp. Med. 150:580.
20. Schuler, G., and R. M. Steinman. 1985. Murine epidermal Langerhans cells mature into potent immunostimulatory dendritic cells in vitro. J Exp. Med. 161:526.
21. Glimcher, L. H., and E. M. Shevach. 1982. Production of autoreactive I region-restricted T cell hybridomas. J Exp. Med. 156:640.
22. Malek, T. R., J. A. Schmidt, and E. M. Shevach. 1985. The murine IL 2 receptor. III. Cellular requirements for the induction of IL 2 receptor expression on T cell subpopulations. J Immunol. 134:2405.
23. Lanier, L. L., G. A. Gutman, D. E. Lewis, S. T. G. Griswold, and N. L. Warner. 1982. Monoclonal antibodies against rat immunoglobulin kappa chains. Hybridoma. 1:125.
24. Rowden G., M. G. Lewis, and A. K. Sullivan. 1977. Ia antigen expression on human epidermal Langerhans cells. Nature (Lond.). 268:247.
25. Klareskog, L., U. Malmnaes-Tjernlund, U. Forsum, and P. A. Peterson. 1977. Epidermal Langerhans’ cells express Ia antigens. Nature (Lond.). 268:248.
26. Stingl, G., E. C. Wolff-Schreiner, W.J. Pichler, F. Gschnait, and W. Knapp. 1977. Epidermal Langerhans cells bear Fc and C3 receptors. Nature (Lond.). 268:245.
27. Breeze, R. G., and E. B. Wheeldon. 1977. The cells of the pulmonary airways. Am. Rev. Respir. Dis. 116:705.
28. Kawanami, O., F. Basset, V.J. Ferrans, P. Soler, and R. G. Crystal. 1981. Pulmonary Langerhans’ cells in patients with fibrotic lung disorders. Lab. Invest. 44:227.
29. Wong, Y. C, and R. C. Buck. 1971. Langerhans cells in epidermoid metaplasia. J Invest. Dermatol. 56:293.
30. Daar, A. S., S. V. Fuggle, J. W. Fabre, A. Ting, and P.J. Morris. 1984. The detailed distribution of MHC class II antigens in normal human organs. Transplantation (Baltimore). 38:293.
31. Forsum, U., L. Klareskog, and P. A. Peterson. 1979. Distribution of Ia-antigen-like molecules on non-lymphoid tissues. Scand. J. Immunol. 9:343.
32. Wiman, K., B. Curman, U. Forsum, L. Klareskog, U. Malmnaes-Tjernlund, L. Rask, L. Traegardh, and P. A. Peterson. 1978. Occurrence of Ia antigens on tissues of non-lymphoid origin. Nature (Lond.). 276:711.
33. Volc-Platzer, B., O. Majdic, W. Knapp, K. Wolff, W. Hinterberger, K. Lechner, and G. Stingl. 1984. Evidence of HLA-DR antigen biosynthesis by human keratinocytes in disease. J Exp. Med. 159:1784.
34. Stein-Streilein, J. 1983. Allergic contact dermatitis induced by intratracheal administration of hapten. J Immunol. 131:1748.
35. Faustman, D. L.(R. M. Steinman, H. M. Gebel, V. Hauptfeld, J. M. Davie, and P. E. Lacy. 1984. Prevention of rejection of murine islet allografts by pretreatment with anti-dendritic cell antibody. Proc. Natl. Acad. Sci. USA. 81:3864.
36. Burke, C. M., J. Theodore, K. D. Dawkins, S. A. Yousem, N. Blank, M. E. Billingham, A. Van Kessel, S. W. Jamieson, P. E. Oyer, J. C. Baldwin, E. B. Stinson, N. E. Shumway, and E. D. Robin. 1984. Post-transplant obliterative bronchiolitis and other late lung sequelae in human heart-lung transplantation. Chest. 86:824.
37. Wyatt, S. E., P. Nunn, J. M. Hows, J. A. L. Yin, M. C. Hayes, D. Catovsky, E. C. Gordon-Smith, J. M. B. Hughes, J. M. Goldman, and D. A. G. Galton. 1984. Airways obstruction associated with graft versus host disease after bone marrow transplantation. Thorax. 39:887.