Positron emission tomography imaging of regional cerebral glucose metabolism

Seminars in Nuclear Medicine

Volumn 16, Issue 1, 1986, Pages 2-34

  Alavi, Abass ^a,b   Dann, Robert ^a,b   Chawluk, John ^a,b   Alavi, Jane ^a,b   Kushner, Michael ^a,b   Reivich, Martin ^a,b  

^a Cerebrovascular Research Center   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DEOXYGLUCOSE; DRUG DERIVATIVE; FLUORODEOXYGLUCOSE F 18; GLUCOSE;

AGING; BRAIN; BRAIN DISEASE; BRAIN TUMOR; CENTRAL NERVOUS SYSTEM DISEASE; CEREBROVASCULAR DISEASE; COMPUTER ASSISTED EMISSION TOMOGRAPHY; DEMENTIA; EPILEPSY; HUMAN; HUNTINGTON CHOREA; METABOLISM; PARKINSON DISEASE; RADIOGRAPHY; REVIEW; SCHIZOPHRENIA; SCINTISCANNING; TISSUE DISTRIBUTION;

AGING; BRAIN; BRAIN DISEASES; BRAIN NEOPLASMS; CENTRAL NERVOUS SYSTEM DISEASES; CEREBROVASCULAR DISORDERS; DEMENTIA; DEOXYGLUCOSE; EPILEPSY; FLUDEOXYGLUCOSE F 18; GLUCOSE; HUMAN; HUNTINGTON DISEASE; PARKINSON DISEASE; SCHIZOPHRENIA; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.; TISSUE DISTRIBUTION; TOMOGRAPHY, EMISSION-COMPUTED;

EID: 0022567676     PISSN: 00012998     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0001-2998(86)80002-2     Document Type: Article

References (133)

1. 14C]deoxyglucose method for the measurement of local cerebral glucose utilization: Theory, procedure and normal values in the conscious and anesthetized albino rat
2. Hexose translocation across the blood-brain interface: Configurational aspects
3. Substrate specificity of brain hexokinase
4. 18F]-fluorodeoxyglucose method for the measurement of local cerebral glucose utilization in man
5. Tomographic measurement of local cerebral glucose metabolic rate in humans with (F-18) 2-fluoro-2-deoxy-d-glucose. Validation of method
6. Nonivasive determination of local cerebral metabolic rate of glucose in man
7. Functional imaging of the brain with positron emission tomography
8. Study of cerebral function with positron computed tomography
9. Transaxial emission reconstruction tomography: Coincidence detection of positron emitting radionuclides
10. 11C]deoxyglucose
11. 18F]-2-fluoro-2-deoxy-d-glucose
12. Effect of ischemia on quantification of local cerebral glucose metabolic rate in man
13. Cerebral glucose metabolism as a function of age in man: Influence of the rate constants in the fluorodeoxyglucose method
14. Kinetics of transport and phosphorylation of 2-fluoro-2-deoxy-d-glucose in rat brain
15. Comparative regional analysis of 2-fluorodeoxyglucose and methylglucose uptake in brain of four stroke patients. With special reference to the regional estimation of the lumped constant
16. Quantitation in positron emission tomography. 1. Effect of object size
17. Quantitation in positron emission computed tomography. 2. Effect of inaccurate attentuation correction
18. Quantitation in positron emission computed tomography. 3. Effect of sampling
19. Quantitation in positron emission tomography. 4. Effect of accidental coincidences
20. Quantitation in positron emission computed tomography. 6. Effect of nonuniform resoltuion
21. Quantitation in positron emission computed tomography. 5. Physical-anatomical effects
22. Error sensitivity analysis of fluorodeoxyglucose method for measurement of cerebral metabolic rate of glucose
23. Prospects for both precision and accuracy in positron emission tomography
24. The subdivisions of neocortex: A proposal to revise the traditional view of sensory, motor, and association areas
25. Principles of organization of sensory-perceptual systems in mammals
26. Metabolic mapping of functional activity in man with 18F-fluoro-deoxyglucose technique
27. Tomographic mapping of human cerebral metabolism: Sensory deprivation
28. Tomographic mapping of human cerebral metabolism. Normal unstimulated state
29. Positron brain, imaging—Normal patterns and asymmetries
30. The Structure and Functions of the Brain
31. The topography and variability of the primary visual cortex in man
32. 11C]glucose for the determination of local cerebral glucose metabolism in humans: Variation within and between subjects
33. A strategy for obtaining both resting and psychologically activated state metabolic data from a single PET study using [F-18]-fluorodeoxyglucose (FDG)
34. Test-retest studies of glucose metabolic rate with F-18-deoxyglucose
35. Design considerations for a whole body positron emission transaxial tomograph (PETT III)
36. Mapping of functional activity in brain with 18-F-fluorodeoxyglucose
37. ECAT: A new computerized tomographic imaging system for positron emitting radiopharmaceuticals
38. Positron emission tomography: Human brain function and biochemistry
39. Human brain: Left-right asymmetries in temporal speech region
40. Anatomic variations in the cortex: Individual differences and the problem of the localization of language functions
41. Tomographic mapping of human cerebral metabolism. Auditory stimulation
42. Multiple cortical visual areas: Visual field topography in the cat
43. Visual topography and function: Cortical visual areas in the owl monkey
44. Cortical visual areas of the temporal lobe: Three areas in the Macaque
45. Metabolic mapping of the brain's response to visual stimulation Studies in man
46. Design considerations for a positron emission tomograph (PETT V) for imaging of the brain
47. Stimulus rate dependence of regional cerebral blood flow in human striate cortex, demonstrated by positron emission tomography
48. Ischemic lesions of the occipital cortex and optic radiations: Positron emission tomography
49. Tomographic mapping of human cerebral metabolism: Visual stimulation and deprivation
50. Computer aided data analysis of ECT data
51. Anatomical localization schemes for use in positron computed tomography using a speciall designed headholder
52. A stereotactic method of anatomical localization for positron emission tomography
53. Computer assisted mapping in quantitative analysis of cerebral positron emission tomography
54. A computerized system for the elastic matching of deformed radiographic images to idealized atlas imaging
55. The construction of a computerized individually adjustable stereotaxic brain atlas for use in neurosurgery and PET studies
56. Physiologic neuroanatomy: New brain imaging methods present a challenge to an old discipline
57. Brain region localization in positron emission tomographic images
58. Cerebral metabolic relationships for selected brain regions in healthy adults
59. Intercorrelations of glucose metabolic rates between brain regions: Application to healthy males in a state of reduced sensory input
60. Human brain development in infants with PET and FDG
61. Effects of human aging on patterns of local cerebral glucose utilization determined by the [18F] fluorodeoxyglucose method
62. Determination of cerebral metabolism in senile dementia using F-18-deoxyglucose and positron emission tomography
63. Determination of regional cerebral metabolism in dementia using F-18 deoxyglucose and positron emission tomography
64. Positron emission tomography in the study of aging and senile dementia
65. Positron emission tomography in dementia
66. Positron emission tomographic studies of aging and Alzheimer disease
67. Brain aging in 40 healthy men: rCMRglu and correlated functional activity in various brain regions in the resting state
68. Positron emission tomography and computerized tomography of the aging brain
69. Correlative imaging of the brain in aging and dementia with positron emission tomography, x-ray computed tomography and magnetic resonance imaging
70. Determination of patterns of regional cerebral glucose metabolism in normal aging and dementia
71. Altered patterns of regional cerebral glucose metabolism in aging and dementia
72. Regional cerebral oxygen supply and utilization in dementia
73. Alzheimer's disease: Focal cortical changes shown by PET
74. Regional cortical dysfunction in Alzheimer's disease as determined by positron emission tomography
75. Regional cerebral metabolic alterations in dementia of the Alzheimer type: Positron emission tomography with [18F] fluorodeoxyglucose
76. Correlative studies of the brain with positron emission tomography, nuclear magnetic resonance, and x-ray computed tomography
77. PET measurements of cerebral metabolism corrected for CSF contributions
78. Patterns of local cerebral glucose utilization determined in Parkinson's disease by the [18F] fluorodeoxyglucose method
79. Similarities of cerebral glucose metabolism in Alzhemier's and parkinsonian demetia
80. Cerebral metabolism and atrophy in Huntington's disease determined by FDG and CT scan
81. Cerebral glucose utilization and blood flow in Huntington's disease
82. Correlations of positron emission scans with TCT scans and clinical course
83. 3
84. Local and remote metabolic disturbances following acute cerebral infarction
85. The luxury perfusion syndrome and its possible relation to acute metabolic acidosis localized within the brain
86. Noninvasive tomographic study of cerebral blood flow and oxygen metabolism in vivo
87. 2) and oxygen extraction ratio (OER) in acute hemispheric stroke
88. Local CBF, oxygen extraction fraction (OEF), and CMRO2: Prognostic value in recent supratentorial infarction in humans
89. Cerebral oxygen metabolism and blood flow in human cerebral ischemic infarction
90. Coupling between regional blood flow and oxygen utilization in the normal human brain A study with positron emission tomography and oxygen
91. Blood flow metabolism couple in brain
92. Disturbance of oxidative metabolism of glucose in recent human cerebral infarcts
93. Local interrelationships of cerebral oxygen consumption and glucose utilization in normal subjects and in ischemic stroke patients: A positron emission tomography study
94. Tissue acid-base balance and oxygen metabolism in human cerebral infarction studied with positron emission tomography
95. Effect of ischemia on known substrates and cofactors of the glycolytic pathway in brain
96. Evaluation of cerebral perfusion reserve in patients with carotidartery occlusion
97. Physiological responses to focal cerebral ischemia in humans
98. Crossed cerebellar diaschisis: A remote functional depression secondary to supratentorial infarction of man
99. Contralateral cerebellar hypometabolism following cerebral insult: A positron emission tomography study
100. Serial observations on the pathophysiology of acute stroke: The transition from ischaemia to infarction as reflected in regional oxygen extraction
101. Experimental study of distant effects of acute focal brain injury
102. Metabolic effects of seizures
103. Cerebral metabolic and circulation responses to induced convulsions in animals
104. Functional localization of eliptogenic lesions
105. Correlative studies of the brain with positron emission tomography (PET), nuclear magnetic resonance (NMR) and x-ray computed tomography (XCT)
106. Interictal cerebral glucose metabolism in partial epilepsy and its relation to EEG changes
107. Comparative localization of epileptic foci in partial epilepsy by PCT and EEG
108. Pathological findings underlying focal temporal lobe hypometabolism in partial epilepsy
109. Correlation of criteria used for localizing epileptic foci in patients considered for surgical therapy of epilepsy
110. 3
111. Local cerebral metabolism during partial seizures
112. Patterns of human local cerebral glucose metabolism during epileptic seizures
113. Local cerebral metabolic rate for glucose during petit mal absences
114. [18f] fluorodeoxyglucose positron emission computed tomography in refractory complex seizures
115. Positron emission tomography in two cases of childhood epileptic encephalopathy (Lennox-Gastaut syndrome)
116. 15F) flurodeoxyglucose and positron emission tomography
117. Glycolytic rate (PET) and contrast enhancement (CT) in human cerebral gliomas
118. Depressed cerebellar glucose metabolism in supratentorial tumors
119. Positron emission tomographic study of suppression of gray matter glucose utilization by brain tumors
120. 18F) flurodeoxyglucose and positron emission tomography in the evaluation of radiation necrosis of the brain
121. Metabolic brain imaging correlated with clinical features and brain tumors
122. Prediction of survival in glioma patients by means of positron emission tomography
123. Cerebral glucography with positron emission tomography
124. Regional brain glucose metabolism schizophrenia
125. Persistence and cerebral metabolic abnormalities in chronic schizophrenia as determined by positron emission tomography
126. 15O positron emission tomographic scanning in predominantly never treated acute schizophrenia patients
127. Positron emission tomographic study of affective disorders: Problems and strategies
128. Correlative studies of the brain positron emission tomography (PET), magnetic resonance imaging (MRI) and x-ray computed tomography (XCT)