Inhibition of 5-hydroxy-eicosatetraenoic acid (5-HETE) formation in intact human neutrophils by naturally-occurring diarylheptanoids: inhibitory activities of curcuminoids and yakuchinones

Prostaglandins, Leukotrienes and Medicine

Volumn 22, Issue 3, 1986, Pages 357-360

  Flynn, Daniel L ^a   Rafferty, Michael F ^a   Boctor, Amal M ^a  

^a PFIZER INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3 AMINO 1 (3 TRIFLUOROMETHYLPHENYL) 2 PYRAZOLINE; 5 HYDROXYICOSATETRAENOIC ACID; ANTIINFLAMMATORY AGENT; ARACHIDONIC ACID; CALCIMYCIN; CURCUMIN; DOCEBENONE; PHENIDONE;

ARACHIDONIC ACID METABOLISM; BLOOD AND HEMOPOIETIC SYSTEM; CURCUMINOID; DINORCURCUMIN; DRUG EFFICACY; HUMAN; HUMAN CELL; IN VITRO STUDY; NEUTROPHIL; NORMAL HUMAN; PRIORITY JOURNAL; YAKUCHINONE; YAKUCHINONE A; YAKUCHINONE B;

CATECHOLS; CURCUMIN; GUAIACOL; HUMAN; HYDROXYEICOSATETRAENOIC ACIDS; IN VITRO; NEUTROPHILS;

EID: 0022550216     PISSN: 02621746     EISSN: None     Source Type: Journal    
DOI: 10.1016/0262-1746(86)90146-0     Document Type: Article

References (12)

1. Preliminary study on antirheumatic activity of curcumin (diferuloyl methane)
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3. Modification of certain inflammation-induced biochemcial changes by curcumin
4. Two New Diarylheptanoids from Alpinia officinarum Hance
5. A Pungent Principle from Alpinia oxyphylla
6. Folk remedies Point to New Drugs
7. Arachidonic acid metabolism in polymorphonuclear leukocytes. Effects of ionophore A23187
8. Prostaglandin endoperoxide metabolism by microsomes of whole kidneys from normal, congential unilateral hydronephrotic and unilateral uteteral obstructed rats
9. A synthesis of Curcumin and Related Compounds
10. Synthesis of Diarylheptanoids and assessment of their pungency