Hemiparkinsonism in a monkey after unilateral internal carotid artery infusion of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) is associated with regional ipsilateral changes in striatal dopamine D-2 receptor density

Brain Research

Volumn 382, Issue 2, 1986, Pages 360-364

  Joyce, Jeffrey N ^a   Marshall, John F ^a   Bankiewicz, Krzysztof S ^b   Kopin, Irwin J ^b   Jacobowitz, David M ^c  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b Surgical Neurology Branch NINCDS ^*  (United States)

^c NATIONAL INSTITUTE OF MENTAL HEALTH   (United States)

Author keywords

caudate nucleus; dopamine denervation; primate; putamen; 3H mazindol; 3H spiroperidol

Indexed keywords

1,2,3,6 TETRAHYDRO 1 METHYL 4 PHENYLPYRIDINE; BUTACLAMOL; KETANSERIN; LEVODOPA; MAZINDOL H 3; OXIDOPAMINE; RADIOISOTOPE; SPIPERONE H 3; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CENTRAL NERVOUS SYSTEM; DRUG RECEPTOR BINDING; INTOXICATION; INTRAARTERIAL DRUG ADMINISTRATION; MONKEY; NERVOUS SYSTEM; NEUROTOXICITY; NONHUMAN; PHARMACOKINETICS; PRIORITY JOURNAL;

1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE; ANIMALS; AUTORADIOGRAPHY; CAROTID ARTERIES; CORPUS STRIATUM; DISEASE MODELS, ANIMAL; FEMALE; FUNCTIONAL LATERALITY; INFUSIONS, INTRA-ARTERIAL; MACACA FASCICULARIS; PARKINSON DISEASE, SECONDARY; PYRIDINES; RECEPTORS, DOPAMINE; RECEPTORS, DOPAMINE D2; SPIPERONE; TRITIUM;

EID: 0022543572     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/0006-8993(86)91345-4     Document Type: Article

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