Thromboxane Synthetase Inhibitors and Antihypertensive Agents. 1. N-[(1H-Imidazol-1-yl)alkyl]aryl Amides and N-[(1H-1,2,4-Triazol-1-yl)alkyl]aryl Amides

Journal of Medicinal Chemistry

Volumn 29, Issue 4, 1986, Pages 523-530

  Wright, William B ^a   Chan, Peter S ^a   Marsico, Joseph W ^a   Lucas, Judy ^a   Tauber, Jess ^a   Tomcufcik, Andrew S ^a   Haug, Margie F ^a   Press, Jeffery B ^b  

^a WYETH RESEARCH   (United States)

^b Ortho McNeil Pharmaceutical Incorporated   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIHYPERTENSIVE AGENT; DAZOXIBEN; ENZYME; ENZYME INHIBITOR; IMIDAZOLE DERIVATIVE; N [3 (1H 1,2,4 TRIAZOL 1 YL)PROPYL]BENZAMIDE DERIVATIVE; N [3 (1H IMIDAZOL 1 YL)PROPYL]BENZAMIDE DERIVATIVE; N [OMEGA (1H 1,2,4 TRIAZOL 1 YL)ALKYL]BENZAMIDE DERIVATIVE; N [OMEGA (1H IMIDAZOL 1 YL)ALKYL]BENZAMIDE DERIVATIVE; NEW DRUG; PROSTACYCLIN; THROMBOXANE B2; THROMBOXANE SYNTHASE; TRIAZOLE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD AND HEMOPOIETIC SYSTEM; CARDIOVASCULAR SYSTEM; DRUG ANALYSIS; DRUG COMPARISON; DRUG EFFICACY; DRUG IDENTIFICATION; DRUG SCREENING; DRUG SYNTHESIS; GREAT BLOOD VESSEL; GUINEA PIG; HYPERTENSION; IN VITRO STUDY; NONHUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; RAT; STRUCTURE ACTIVITY RELATION;

EID: 0022543005     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm00154a017     Document Type: Article

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