Quantitative autoradiographic localization of the dopamine transport complex in the rat brain: use of a highly selective radioligand: [3H]GBR 12935

European Journal of Pharmacology

Volumn 126, Issue 1-2, 1986, Pages 171-173

  Dawson, Ted M ^a,b   Gehlert, Donald R ^b   Wamsley, James K ^a,b  

^a UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^b NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1 [2 (BENZHYDRYLOXY)ETHYL] 4 (3 PHENYLPROPYL)PIPERAZINE H 3; DOPAMINE RECEPTOR; DOPAMINE RECEPTOR BLOCKING AGENT; RADIOISOTOPE; UNCLASSIFIED DRUG;

1 [2 (BENZHYDRYLOXY)ETHYL] 4 (3 PHENYLPROPYL)PIPERAZINE H 3; ANIMAL CELL; AUTORADIOGRAPHY; CENTRAL NERVOUS SYSTEM; DOSE RESPONSE; DRUG DISTRIBUTION; DRUG RECEPTOR BINDING; DRUG RESPONSE; IN VITRO STUDY; METHODOLOGY; NERVOUS SYSTEM; NONHUMAN; PHARMACOKINETICS; PRELIMINARY COMMUNICATION; PRIORITY JOURNAL; RAT;

ANIMAL; AUTORADIOGRAPHY; BRAIN; DOPAMINE; IN VITRO; LIGANDS; MALE; NERVE ENDINGS; PIPERAZINES; RADIOLIGAND ASSAY; RATS; RATS, INBRED STRAINS; RECEPTORS, DOPAMINE; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.;

EID: 0022542919     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/0014-2999(86)90757-0     Document Type: Article

References (5)

1. Dopamine-containing systems in the CNS
2. Dawson, T.M., D.R. Gehlert and J.K. Wamsley, Quantitative autoradiographic localization of central dopamine D-1 and D-2 receptors, in: Dopamine Receptor Function and Biochemistry, eds. I. Creese and G. Breese (Plenum Press, New York, NY) (in press).
3. Behavioral properties of GBR 12909, GBR 13069 and GBR 13098: specific inhibitors of dopamine uptake
4. 3H]-GBR 12935 binding in brain: A radioligand for selective labelling of the dopamine transport complex
5. Aryl 1,4-dialk(en)ylpiperazines as selective and very potent inhibitors of dopamine uptake