Considerations for the Design of Nitrophenyl Mustards as Agents with Selective Toxicity for Hypoxic Tumor Cells

Journal of Medicinal Chemistry

Volumn 29, Issue 6, 1986, Pages 879-887

  Denny, William A ^a   wilson, William R ^a  

^a UNIVERSITY OF AUCKLAND   (New Zealand)

Author keywords

[No Author keywords available]

Indexed keywords

5 (1 AZIRIDINYL) 2,4 DINITROBENZAMIDE; ANTINEOPLASTIC AGENT; MISONIDAZOLE; NITRACRINE;

CANCER CHEMOTHERAPY; DRUG COMPARISON; DRUG CYTOTOXICITY; DRUG DESIGN; DRUG MECHANISM; DRUG SOLUBILITY; HYPOXIA; INTOXICATION; N,N BIS(2 CHLOROETHYL) 3 NITROANILINE; N,N BIS(2 CHLOROETHYL) 4 NITROANILINE; N,N BIS(2 CHLOROETHYL) 4 NITROANILINE DERIVATIVE; NONBIOLOGICAL MODEL; NONHUMAN; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION; THEORETICAL STUDY; THERAPY;

ALKYLATING AGENTS; ANIMAL; ANTINEOPLASTIC AGENTS; FREE RADICALS; HUMAN; HYDROGEN-ION CONCENTRATION; MUSTARD COMPOUNDS; OXYGEN; SOLUBILITY; STRUCTURE-ACTIVITY RELATIONSHIP; SUPPORT, NON-U.S. GOV'T;

EID: 0022535929     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm00156a001     Document Type: Article

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