Effects of griseofulvin on enzymes associated with phase I and II of drug metabolism

Biochemical Pharmacology

Volumn 35, Issue 15, 1986, Pages 2630-2632

  Williams, Marvin T ^a   Simonet, Lizette ^a  

^a UNIVERSITY OF SOUTH FLORIDA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME P450; GRISEOFULVIN;

ANIMAL EXPERIMENT; DRUG EFFICACY; DRUG METABOLISM; IN VITRO STUDY; INTOXICATION; LIVER; LIVER MICROSOME; LIVER TOXICITY; NONHUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; RAT;

ANIMAL; ARYL HYDROCARBON HYDROXYLASES; CYTOCHROME P-450 ENZYME SYSTEM; GRISEOFULVIN; HEME; MALE; METYRAPONE; MICROSOMES, LIVER; NADPH-FERRIHEMOPROTEIN REDUCTASE; PHARMACEUTICAL PREPARATIONS; RATS; RATS, INBRED STRAINS; SUPPORT, NON-U.S. GOV'T;

EID: 0022529080     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/0006-2952(86)90065-1     Document Type: Article

References (20)

1. DISTURBANCE OF PORPHYRIN METABOLISM CAUSED BY GRISEOFULVIN IN MICE.
2. PROTOPORPHYRIN, CIRRHOSIS AND HEPATOMATA IN THE LIVERS OF MICE GIVEN GRISEOFULVIN.
3. Behavior of hepatic microsomal cytochromes after treatment of mice with drugs known to disturb porphyrin metabolism in liver
4. A comparison of mouse and rat liver enzymes and their response to treatment with various compounds
5. The Molar Light Absorption of Pyridine Ferroprotoporphrin (Pyridine Haemochromogen).
6. Reduced nicotinamide adenine dinucleotide-cytochrome b5 reductase and cytochrome b5 as electron carriers in NADH-supported cytochrome P-450-dependent enzyme activities in liver microsomes
7. Radioactive assay for aryl hydrocarbon hydroxylase. Improved method and biological importance