Cooperative binding of λ repressors to sites separated by integral turns of the DNA helix

Cell

Volumn 44, Issue 5, 1986, Pages 681-687

  Hochschild, A ^a   Ptashne, M ^a  

^a HARVARD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA HELIX; GENETIC ENGINEERING; LAMBDA REPRESSOR; NONHUMAN; PRIORITY JOURNAL;

BASE SEQUENCE; BINDING SITES; DEOXYRIBONUCLEASE I; DNA; DNA-BINDING PROTEINS; KINETICS; MODELS, MOLECULAR; NUCLEIC ACID CONFORMATION; OPERATOR REGIONS (GENETICS); REPRESSOR PROTEINS; STRUCTURE-ACTIVITY RELATIONSHIP; SUPPORT, U.S. GOV'T, P.H.S.; TRANSCRIPTION FACTORS;

EID: 0022521842     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/0092-8674(86)90833-0     Document Type: Article

References (31)

1. Quantitative model for gene regulation by λ phage repressor
2. The λ and 434 phage repressors
3. Two operator sites separated by 599 base pairs are required for deoR repression of the deo operon of Escherichia coli
4. pEMBL: a new family of single stranded plasmids
5. DNA bending and its relation to nucleosome positioning
6. An operator at −280 base pairs that is required for repression of araBAD operon promoter: addition of DNA helical turns between the operator and promoter cyclically hinders repression
7. Flexibility of native DNA from the sedimentation behavior as a function of molecular weight and temperature
8. Yeast promoters: positive and negative elements
9. Upstream repression and CRP stimulation of the Escherichia coli L-arabinose operon
10. Tortional rigidity of DNA and length dependence of the free energy of DNA supercoiling
11. A control element within a structural gene: the gal operon of Escherichia coli
12. Mechanism of action of the lambda Cro protein
13. Interactions between DNA-bound repressors govern regulation by the λ phage repressor
14. Mapping the topography of DNA wrapped around gyrase by nucleolytic and chemical probing of complexes of unique DNA sequences
15. Bacterial DNA topoisomerase I can relax positively supercoiled DNA containing a single-stranded loop
16. Sequence-dependent variation in the conformation of DNA
17. Kinetic analysis of deoxyribonuclease I cleavages in the nucleosome core: evidence for a DNA superhelix
18. Demonstration of two operator elements in gal: in vitro repressor binding studies
19. Sequencing end-labeled DNA with base-specific chemical cleavages
20. Contacts between DNA gyrase and its binding site on DNA: features of symmetry and asymmetry revealed by protection from nucleases
21. The operator-binding domain of λ repressor: structure and DNA recognition
22. The λ repressor contains two domains
23. Structure of the nucleosome core particle at 7A resolution
24. Molecular characterization of the repressor and its gene cl
25. Regulatory functions of the λ repressor reside in the amino-terminal domain
26. Interaction of a gene-specific transcription factor with the adenovirus major late promoter upstream of the TATA box region
27. Enhancers and eukaryotic gene transcription
28. Energetics of DNA twisting: I. Relation between twist and cyclization probability
29. The locus of sequence directed and protein-induced DNA bending
30. Oligonucleotide directed mutagenesis of DNA fragments cloned into M13-derived vectors