The effect of moderate urine alkalinisation on low dose diethylcarbamazine therapy in patients with onchocerciasis.

British Journal of Clinical Pharmacology

Volumn 21, Issue 6, 1986, Pages 669-676

  Awadzi, K ^a   Adjepon‐Yamoah, KK ^a   Edwards, G ^a   Orme, ML ^a   Breckenridge, AM ^a   Gilles, HM ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

BICARBONATE; DIETHYLCARBAMAZINE;

CLINICAL ARTICLE; DRUG DOSE; DRUG EFFICACY; DRUG ELIMINATION; DRUG EXCRETION; DRUG THERAPY; DRUG URINE LEVEL; FILARIA; HUMAN; KIDNEY; MACROFILARIA; MICROFILARIASIS; ONCHOCERCA VOLVULUS; ONCHOCERCIASIS; ORAL DRUG ADMINISTRATION; PHARMACOKINETICS; PRIORITY JOURNAL; THERAPY;

ADOLESCENT; ADULT; BICARBONATES; DIETHYLCARBAMAZINE; DRUG THERAPY, COMBINATION; HUMANS; HYDROGEN-ION CONCENTRATION; KINETICS; LEUKOCYTE COUNT; MALE; MICROFILARIA; MIDDLE AGED; ONCHOCERCA; ONCHOCERCIASIS; RANDOM ALLOCATION; SODIUM; SODIUM BICARBONATE; TRANSAMINASES;

EID: 0022520901     PISSN: 03065251     EISSN: 13652125     Source Type: Journal    
DOI: 10.1111/j.1365-2125.1986.tb05232.x     Document Type: Article

References (24)

1. Topical diethylcarbamazine in ocular onchocerciasis
2. Topical diethylcarbamazine in ocular onchocerciasis
3. The chemotherapy of onchocerciasis II. Quantitation of the clinical reaction to microfilaricides
4. Therapy of tropical diseases—filariasis
5. The chemotherapy of Onchocerciasis VII. The effect of prednisone on the Mazzotti reaction
6. The chemotherapy of onchocerciasis IX. The effect of prednisone plus cyproheptadine on the Mazzotti reaction
7. The chemotherapy of onchocerciasis X. An assessment of four single dose treatment regimes of MK‐933 (ivermectin) in human onchocerciasis
8. Topical Hetrazan in the treatment of ocular onchocerciasis
9. Onchocerciasis and its treatment
10. Onchocerciasis
11. The effect of variations in urinary pH on the pharmacokinetics of diethylcarbamazine
12. Die‐ethylcarbamazine disposition in patients with onchocerciasis
13. The Mazzotti reaction following treatment of onchocerciasis with diethylcarbamazine; clinical severity as a function of infection intensity
14. Adverse reactions to cutaneous diethylcarbamazine in onchocerciasis
15. Effects of various concentrations of diethylcarbamazine citrate applied as eye drops in ocular onchocerciasis, and the possibilities of improved therapy from continuous non‐pulsed delivery
16. A trans‐epidermal chemotherapy of onchocereiasis
17. Topical diethylcarbamazine in the treatment of ocular onchocerciasis
18. Possibilidad de utilizar como medio diagnostico en la onchocercosis las reacciones alergicas consecutivas a la administration de “Heterozan”
19. Chimiotherapie de l'onchocercose. I. Essais de traitement de masse par lar diethylcarbamazine, le levamisole et l'association diethylcarbamazine et levamisole
20. Chimiotherapie de l'on‐chocerçise. II. Evaluation de l'activite de deux schemas therapeutiques associant diethylcarbamazine et levamisole sur la densite micro‐filarienne d'Onchocerca volvulus (Leuckart, 1893)
21. Plasma levels of diethylcarbamazine in man
22. Long term treatment of onchocerciasis in children with low doses of diethylcarbamazine
23. Chemotherapy of onchocerciasis; a controlled clinical trial of topical diethylcarbamazine (DEC) in Guatemala
24. Ocular changes with oral and transepidermal diethylcarbamazine therapy of onchocerciasis