Differential Effects of Transforming Growth Factor-βon Proliferation of Normal and Malignant Rat Liver Epithelial Cells in Culture

Cancer Research

Volumn 46, Issue 9, 1986, Pages 4665-4671

  Richards, William L ^b   Song, Min Kyung H ^b   Thorgeirsson, Snorri S ^b  

^a NATIONAL INSTITUTES OF HEALTH   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AFLATOXIN B1; RADIOISOTOPE; TRANSFORMING GROWTH FACTOR; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL CELL; CELL CULTURE; CELL GROWTH; COLONY FORMATION; DNA SYNTHESIS; DRUG EFFICACY; GROWTH INHIBITION; HISTOLOGY; IN VITRO STUDY; LIVER; LIVER CELL; MALIGNANT TRANSFORMATION; METHODOLOGY; NONHUMAN; PRIORITY JOURNAL; RAT; TOPICAL DRUG ADMINISTRATION; TUMOR CELL;

AFLATOXIN B1; AFLATOXINS; ANIMALS; CELL CYCLE; CELL TRANSFORMATION, NEOPLASTIC; CELLS, CULTURED; EPITHELIAL CELLS; GROWTH INHIBITORS; LIVER; LIVER NEOPLASMS; MICROSCOPY, ELECTRON; PEPTIDES; RATS; TRANSFORMING GROWTH FACTORS;

EID: 0022519967     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: None     Document Type: Article

References (30)

1. James, R., and Bradshaw, R. A. Polypeptide growth factors. Annu. Rev. Biochem., 53: 259–292, 1984.
2. Holley, R. W., Armour, R., Baldwin, J. H., and Greenfield, S. Activity of a kidney epithelial cell growth inhibitor on lung and mammary cells. Cell Biol. Int. Rep., 7: 141-147, 1983.
3. Holley, R. W., Bohlen, P., Fava, R., Baldwin, J. H., Kleeman, G., and Armour, R. Purification of kidney epithelial cell growth inhibitors. Proc. Natl. Acad. Sci. USA, 77: 5989–5992, 1980.
4. McMahon, J. B., Farrelly, J. G., and Iype, P. T. Purification and properties of a rat liver protein which specifically inhibits the proliferation of nonmalignant rat liver epithelial cells. Proc. Natl. Acad. Sci. USA, 79: 456-460, 1982.
5. DeLarco, J. E., and Todaro, G. J. Growth factors from murine sarcoma virus-transformed cells. Proc. Natl. Acad. Sci. USA, 75: 4001-4005, 1978.
6. Todaro, G. J., DeLarco, J. E., Fryling, C., Johnson, P. A., and Sporn, M. B. Transforming growth factors (TFGs): properties and possible mechanisms of action. J. Supramol. Struct. Mol. Biochem., 15: 287-301, 1981.
7. Carpenter, G., Stoscheck, C. M., Preston, Y. A., and DeLarco, J. E. Antibodies to the epidermal growth factor receptor block the biological activities of sarcoma growth factor. Proc. Natl. Acad. Sci. USA, 80: 5627-5630, 1983.
8. Anzano, M. A., Roberts, A. B., Meyers, C. A., Komoriya, A., Lamb, L. C., Smith, J. M., and Sporn, M. B. Synergistic interaction of two classes of transforming growth from murine sarcoma cells. Cancer Res., 42: 4776–4778, 1982.
9. Anzano, M. A., Roberts, A. B., Smith, J. M., Sporn, M. B., and DeLarco, J. E. Sarcoma growth factor from conditioned medium of virally transformed cells is composed of both type α and β transforming growth factors. Proc. Natl. Acad. Sci. USA, 80: 6264-6268, 1983.
10. Assoian, R. K., Komoriya, A., Meyers, C. A., and Sporn, M. B. Transforming growth factor-β in human platelets: identification of a major storage site, purification, and characterization. J. Biol. Chem., 258: 7155-7160, 1983.
11. Roberts, A. B., Anzano, M. A., Lamb, L. C., Smith, J. M., Frolik, C. A., Marquardt, H., Todaro, G. J., and Sporn, M. B. Isolation from murine sarcoma cells of novel transforming growth factors potentiated by EGF. Nature (Lond.), 295: 417-419, 1982.
12. Roberts, A. B., Anzano, M. A., Lamb, L. C., Smith, J. M., and Sporn, M. B. New class of transforming growth factors potentiated by epidermal growth factors: isolation from non-neoplastic tissues. Proc. Natl. Acad. Sci. USA, 78: 5339-5343, 1981.
13. Frolik, C. A., Dart, L. L., Meyers, C. A., Smith, D. M., and Sporn, M. B. Purification and initial characterization of a type β transforming growth factor from human placenta. Proc. Natl. Acad. Sci. USA, 80: 3676–3680, 1983.
14. Marquardt, H., Hunkapiller, M. W., Hood, L. E., and Todaro, G. J. Rat transforming growth factor type 1: structure and relation to epidermal growth factor. Science (Wash. DC), 223: 1079-1082, 1984.
15. Nickell, K. A., Halper, J., and Moses, H. L. Transforming growth factors in solid human malignant neoplasms. Cancer Res., 43: 1966-1971, 1983.
16. Roberts, A. B., Anzano, M. A., Meyers, C. A., Wideman, J., Blacher, R., Pan, Y-C. E., Stein, S., Lehrman, S. R., Smith, J. M., Lamb, L. C., and Sporn, M. B. Purification and properties of type β transforming growth factor from bovine kidney. Biochemistry, 22: 5692-5698, 1983.
17. Salomon, D. A., Zwiebel, J. A., Bano, M., Losonezy, I., Fehnel, P., and Kidwell, W. R. Presence of transforming growth factors in human breast cancer cells. Cancer Res., 44: 4069-4077, 1984.
18. Roberts, A. B., Anzano, M. A., Wakefield, L. M., Roche, N. S., Stern, D. F., and Sporn, M. B. Typeβ transforming growth factor: a bifunctional regulator of cellular growth. Proc. Natl. Acad. Sci. USA, 82: 119-123, 1985.
19. Tucker, R. F., Shipley, G. D., Moses, H. L., and Holley, R. W. Growth inhibitor from BSC-1 cells closely related to platelet type β transforming growth factor. Science (Wash. DC), 226: 705-707, 1984.
20. Herring, A. S., Raychaudhuri, R., Kelley, S. P., and lype, P. T. Repeated establishment of diploid epithelial cell culture from normal and partially hepatectomized rats. In Vitro (Rockville), 19: 576-588, 1983.
21. Evarts, R. P., Marsden, E., Hanna, P., Wirth, P. J., and Thorgeirsson, S. S. Isolation of preneoplastic rat liver cells by centrifugal elutriation and binding to asialofetuin. Cancer Res., 44: 5718-5724, 1984.
22. Song, M., Krutzsch, H., Hankins, W. D., Richards, W. L., and Thorgeirsson, S. S. Rapid determination of DNA synthesis in adherent cells grown in microtiter plates. Exp. Cell Res., 156: 271-276, 1985.
23. Richards, W. L., Song, M-K., Krutzsch, H., Evarts, R. P., Marsden, E., and Thorgeirsson, S. S. Measurement of cell proliferation in microculture using Hoechst 33342 for the rapid semiautomated microfluorimetric determination of chromatin DNA. Exp. Cell Res., 159: 235-246, 1985.
24. Iype, P. T., and McMahon, J. B. Hepatic proliferation inhibitor. Mol. Cell Biochem., 59: 57–80, 1984.
25. McMahon, J. B., and Iype, P. T. Specific inhibition of proliferation of nonmalignant rat hepatic cells by a factor from rat liver. Cancer Res., 40: 1249-1254, 1980.
26. Krstic, R. V. (ed.). Ultrastruktur der Saugetierzelle, pp. 116–121. Berlin: Springer-Verlag, 1976.
27. Reznik-Schuller, H. M., and Haque, B. F., Jr. A morphometric study of the pulmonary Clara cell in normal and nitrosohepatamethyleneimine-treated European hamsters. Exp. Pathol., 18: 366-371, 1980.
28. lype, P. T., and McMahon, J. B. Lack of correlation between the response to a proliferation inhibitor and other transformation markers in a mutant liver cell line. Cancer Res., 41: 3352-3354, 1981.
29. Masui, T., Wakefield, L. M., Lechner, J. F., LaVeck, M. A., Sporn, M. B., and Harris, C. C. Type β transforming growth factor is the primary differentiation-inducing serum factor for normal human bronchial epithelial cells. Proc. Natl. Acad. Sci. USA, 83: 2438-2442, 1986.
30. Yoakum, G. H., Lecher, J. F., Gabrielson, E., Korba, B. E., Malan-Shibley, L., Willey, J. C., Valerio, M. G., Shamsuddin, A. K. M., Trump, B. F., and Harris, C. C. Transformation of human bronchial epithelial cells transfected by Harvey ras oncogene. Science (Wash. DC), 227: 1174-1179, 1985.