The role of 1,25-dihydroxyvitamin D in the inhibition of bone formation induced by skeletal unloading

Endocrinology

Volumn 118, Issue 3, 1986, Pages 948-954

  Halloran, Bernard P ^a   Bikle, Daniel D ^a   Wronski, Thomas J ^b   Globus, Ruth K ^a   Levens, Marilyn J ^a   Morey Holton, Emily ^c  

^a SAN FRANCISCO VETERANS AFFAIRS MEDICAL CENTER   (United States)

^b UNIVERSITY OF FLORIDA   (United States)

^c NASA AMES RESEARCH CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCITRIOL; CALCIUM; PHOSPHORUS;

ANIMAL EXPERIMENT; ANIMAL MODEL; BONE; CYTOLOGY; DRUG EFFICACY; INTRAVENOUS DRUG ADMINISTRATION; NONHUMAN; OSSIFICATION; OSTEOPOROSIS; PRIORITY JOURNAL; RAT;

24,25-DIHYDROXYVITAMIN D 3; BONE AND BONES; CALCIFEDIOL; CALCITRIOL; CALCIUM; DIHYDROXYCHOLECALCIFEROLS; MODELS, BIOLOGICAL; OSTEOBLASTS; OSTEOCLASTS; SPINE; STRESS, MECHANICAL; TIBIA;

EID: 0022515940     PISSN: 00137227     EISSN: 19457170     Source Type: Journal    
DOI: 10.1210/endo-118-3-948     Document Type: Article

References (26)

1. Geiser M, Trueta J 1958 Muscle action, bone rarefaction, and bone formation. J Bone Joint Surg 40B:282
2. Heaney RP 1962 Radiocalcium metabolism in disuse osteoporosis in man. Am J Med 33:188
3. Landry M, Fleisch H 1964 The influence of immobilization on bone formation as evaluated by osseous incorporation of tetracycline. J Bone Joint Surg 46B-.764
4. Burkhart JM, Jowsey J 1967 Parathyroid and thyroid hormones in the development of immobilization osteoporosis. Endocrinology 81:1053
5. Donaldson CL, Hulley SB, Vogel JM, Hattner RS, Bayers JH, McMillan DE 1970 Effect of prolonged bed rest on bone mineral. Metabolism 19:1071
6. Hardt AB 1972 Early metabolic responses of bone to immobilization. J Bone Joint Surg 54A:119
7. Minaire P, Meunier P, Edouard C, Bernard J, Courpron P, Bourret J 1974 Quantitative histological data on disuse osteoporosis. Calcif Tissue Res 17:57
8. Uhthoff HK, Jaworski ZFG 1978 Bone loss in response to long term immobilization. J Bone Joint Surg 60B-.420
9. Wronski TJ, Morey ER 1982 Skeletal abnormalities in rats induced by simulated weightlessness. Metab Bone Dis Rel Res 4:69
10. 3H-collagen from whole bones of rats. J Ortho Res 1:50
11. Globus RK, Bikle DD, Morey-Holton ER 1984 Effects of simulated weightless on bone mineral metabolism. Endocrinology 114:2264
12. Smith MC, Rambaut PC, Vogel JM, Whittle MC 1977 Bone mineral measurement—experiment M078. In: Johnston RS, Diel- tein LF (eds) Biomedical Results from Skylab. NASA SP-377, NASA, Washington DC, p 183
13. Morey ER, Baylink DJ 1978 Inhibition of bone formation during space flight. Science 201:1138
14. Jee WSS, Wronski TJ, Morey ER, Kimmel DB 1983 Effects of spaceflight on trabecular bone in rats. Am J Physiol 244:R310
15. Globus RK, Bikle DD, Morey-Holton ER 1985 The temporal response of bone to unloading. Endocrinology 118:733
16. Milch RA, Rail DP, Tobie JE 1957 Bone localization of the tetracyclines. J Natl Cancer Inst 19:87
17. LeBel D, Poirier GG, Beaudoin AR 1978 A convenient method for the ATPase assay. Anal Biochem 85:86
18. Horst RL, Shepard RM, Jorgensen NA, DeLuca HF 1979 The determination of the vitamin D metabolites on a single plasma sample: changes during parturition in dairy cows. Arch Biochem Biophys 192:512
19. Goldner J 1938 A modification of the Masson trichrome technique for routine laboratory purpose. Am J Pathol 14:237
20. Merz WA, Schenk RK 1970 Quantitative structural analysis of human cancellous bone. Acta Anat 75:54
21. Tapp E 1966 Tetracycline labelling methods of measuring the growth of bones in the rat. J Bone Joint Surg 48B:517
22. Weisbrode SE, Capen CC, Norman AW 1979 Light and electron microscope evaluation of the effects of 1,25-dihydroxyvitamin D on bone of thyroparathyroidectomized rats. Am J Pathol 97:247
23. 3. Lab Invest 48:683
24. Marie PJ, Travers R 1983 Continuous infusion of 1,25-dihydroxyvitamin D stimulates bone turnover in the normal young mouse. Calcif Tissue Intern 35:418
25. Stewart AF, Adler M, Byers CM, Segre GV, Broadus AE 1982 Calcium homeostasis in immobilization: an example of resorptive hypercalcemia. N Engl J Med 306:1136
26. 3: short and long term effects on bone and calcium metabolism in patients with postmenopausal osteoporosis. Proc Natl Acad Sci USA 79:3325