메뉴 건너뛰기




Volumn 123, Issue 1, 1986, Pages 133-143

Dicyclomine, benzhexol and oxybutynine distinguish between subclasses of muscarinic binding sites

Author keywords

( ) 3H QNB binding; Antimuscarinic drugs; Cerebral cortex; Heart; Subtypes of muscarinic receptors; Urinary bladder

Indexed keywords

4 AMINOBUTYRIC ACID; ATROPINE; DIAZEPAM; DICYCLOVERINE; EMEPRONIUM; GLUTAMIC ACID; GLYCINE; HALOPERIDOL; HEXAMETHONIUM; HISTAMINE; IMIPRAMINE; MECAMYLAMINE; METENKEPHALIN; METHYLATROPINE; METHYLSCOPOLAMINE; MORPHINE; MUSCARINIC RECEPTOR; N,N DIMETHYL 3,3 DIPHENYL 2 BUTYLAMINE; NICOTINE; OXYBUTYNIN; PHYSOSTIGMINE; PIRENZEPINE; PRACTOLOL; PRAZOSIN; PROMETHAZINE; PROPANTHELINE BROMIDE; QUINUCLIDINYL BENZILATE; QUINUCLIDINYL BENZILATE H 3; RADIOISOTOPE; SECOVERINE; TERBUTALINE; TERODILINE; THEOPHYLLINE; TRIHEXYPHENIDYL; TUBOCURARINE CHLORIDE; UNCLASSIFIED DRUG; YOHIMBINE;

EID: 0022491102     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/0014-2999(86)90697-7     Document Type: Article
Times cited : (80)

References (45)
  • 2
    • 0017107977 scopus 로고
    • A comparison of affinity constants for muscarine-sensitive acetycholine receptor in guinea-pig atrial pacemaker cells at 29°C and in ileum at 29°C and 37°C
    • (1976) Br. J. Pharmacol. , vol.58 , pp. 613
    • Barlow1    Berry2    Glenton3    Nikolaou4    Soh5
  • 9
    • 0016828210 scopus 로고
    • Quantitative aspects of hormone-receptor interactions of high affinity. Effects of receptor concentration and measurement of dissociation constants of labelled and unlabelled hormones
    • (1975) Biochim. Biophys. Acta , vol.406 , pp. 294
    • Chang1    Jacobs2    Cuatrecasas3
  • 13
    • 0018451220 scopus 로고
    • 3H]Quinuclidinyl benzilate binding to muscarinic receptors in rat brain: Comparison of results from intact brain slcies and homogenates
    • (1979) Br. J. Pharmacol. , vol.65 , pp. 451
    • Gilbert1    Hanley2    Iversen3
  • 16
    • 0018136112 scopus 로고
    • Neurohumoral, hormonal and drug receptors for the lower esophageal sphincter
    • (1978) Gastroenterology , vol.74 , pp. 598
    • Goyal1    Rattan2
  • 18
    • 0020421340 scopus 로고
    • Muscarinic receptor subtypes: M1 and M2, biochemical and functional characterisation
    • (1982) Life Sci. , vol.31 , pp. 2991
    • Hammer1    Giachetti2
  • 27
    • 0021946028 scopus 로고
    • Differential antagonism by dicyclomine, pirenzepine and secoverine at muscarinic receptor sub-types in the rat frontal cortex
    • (1985) European J. Pharmacol. , vol.107 , pp. 287
    • Marchi1    Raiteri2
  • 29
    • 0019980052 scopus 로고
    • Muscarinic receptor binding in the parotid gland. Different affinities of some anticholinergic drugs between the parotid gland and ileum
    • (1982) Scand. J. Gastroenterol. , vol.17 , pp. 69
    • Nilvebrant1    Sparf2
  • 31
    • 0020613467 scopus 로고
    • Differences between binding affinities of some antimuscarinic drugs in the parotid gland and those in the urinary bladder and ileum
    • (1983) Acta Pharmacol. Toxicol. , vol.53 , pp. 304
    • Nilvebrant1    Sparf2
  • 32
    • 0021762037 scopus 로고
    • 3H](−)quinuclidinyl benzilate binding to soluble rat brain muscarinic receptors indicates that pirenzepine binds to an allosteric state of the muscarinic receptor
    • (1984) Biochem. Biophys. Res. Commun. , vol.118 , pp. 950
    • Roeske1    Venter2
  • 35
    • 0020414751 scopus 로고
    • Does pirenzepine distinguish between ‘subtypes’ of muscarinic receptors?
    • (1982) Br. J. Pharmacol. , vol.77 , pp. 567
    • Szelenyi1
  • 38
    • 0021259777 scopus 로고
    • Effects of guanine nucleotide and sulfhydryl reagent on subpopulations of mmuscarinic acetylcholine receptors in mammalian hearts: possible evidence for interconversion of super-high and low-affinity agonist binding-sites
    • (1984) European J. Pharmacol. , vol.100 , pp. 291
    • Uchida1    Matsumoto2    Mizushima3    Osugi4    Higuchi5    Yoshida6
  • 39
    • 0020585963 scopus 로고
    • Muscarinic cholinergic receptor structure. Receptor size, membrane orientation and absence of major phylogenetic structural diversity
    • (1983) J. Biol. Chem. , vol.258 , pp. 4842
    • Venter1
  • 41
    • 0020333849 scopus 로고
    • 3H]Pirenzepine selectively identifies a high-affinity population of muscarinic cholinergic receptors in the rat cerebral cortex
    • (1982) Life Sci. , vol.13 , pp. 2019
    • Watson1    Roeske2    Yamamura3
  • 44
    • 0021263540 scopus 로고
    • A comparison of the antimuscarinic effects of pirenzepine and N-methylatropine on ganglionic and vascular muscarinic receptors in the rat
    • (1984) Life Sci. , vol.35 , pp. 553
    • Wess1    Lambrecht2    Moser3    Mutschler4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.