Tumor necrosis factor (cachectin) is an endogenous pyrogen and induces production of interleukin 1

Journal of Experimental Medicine

Volumn 163, Issue 6, 1986, Pages 1433-1450

  Dinarello, Charles A ^a   Cannon, Joseph G ^a   Wolff, Sheldon M ^a   Bernheim, Harry A ^a   Beutler, Bruce ^b   Cerami, Anthony ^c   Figari, Irene S ^c   Palladino, Michael A ^d   O’Connor, John V ^d  

^a TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b TUFTS UNIVERSITY   (United States)

^c ROCKEFELLER UNIVERSITY   (United States)

^d GENENTECH INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 1; PROSTAGLANDIN; PYROGEN; RADIOISOTOPE; SOYBEAN TRYPSIN INHIBITOR; TRYPSIN; TUMOR NECROSIS FACTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; BLOOD AND HEMOPOIETIC SYSTEM; CENTRAL NERVOUS SYSTEM; DRUG COMPARISON; DRUG CYTOTOXICITY; DRUG DOSE; DRUG EFFICACY; FEVER; INTOXICATION; INTRAVENOUS DRUG ADMINISTRATION; MOUSE; NONHUMAN; PASSIVE TRANSFER; PRIORITY JOURNAL; RABBIT;

ANIMALS; DINOPROSTONE; ENDOTOXINS; FEVER; GLYCOPROTEINS; INTERLEUKIN-1; MICE; MONOCYTES; PROSTAGLANDINS E; PYROGENS; RABBITS; RECOMBINANT PROTEINS; STIMULATION, CHEMICAL; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0022472749     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.163.6.1433     Document Type: Article

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