Barrett's Esophagus

New England Journal of Medicine

Volumn 315, Issue 6, 1986, Pages 362-371

  Spechler, Stuart Jon ^a   Goyal, Raj K ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOCARCINOMA; BARRETT ESOPHAGUS; DYSPLASIA; EPITHELIUM; ESOPHAGITIS; ESOPHAGUS; GASTROESOPHAGEAL REFLUX; HISTOLOGY; HUMAN; PRIORITY JOURNAL; SHORT SURVEY; STOMACH; SURVEY;

EID: 0022469276     PISSN: 00284793     EISSN: 15334406     Source Type: Journal    
DOI: 10.1056/NEJM198608073150605     Document Type: Review

References (104)

1. Goyal RK, Glancy JJ, Spiro HM. Lower esophageal ring. N Engl J Med 1970; 282: 1298–305.
2. Hayward J. The lower end of the esophagus. Thorax 1961; 16: 36–41.
3. Rector LE, Connerley ML. Aberrant mucosa in the esophagus in infants and in children. Arch Pathol 1941; 31: 285–94.
4. De la Pava S, Pickren JW, Adler RH. Ectopic gastric mucosa of the esophagus: a study on histogenesis. NY State J Med 1964; 64: 1831–5.
5. Jabbari M, Goresky CA, Lough J, Yaffe C, Daly D, Cote C. The inlet patch: heterotopic gastric mucosa in the upper esophagus. Gastroenterology 1985; 89: 352–6.
6. Goldman MC. Beckman RC. Barrett syndrome: case report with discussion about concepts of pathogenesis. Gastroenterology 1960; 39: 104–10.
7. Mossberg SM. The columnar-lined esophagus (Barrett syndrome): an acquired condition? Gastroenterology 1966; 50: 671–6.
8. Halvorsen JF, Semb BKH. The Barrett syndrome. (The columnar-lined lower oesophagus): an acquired condition secondary to reflux esophagitis, a case report with discussion of pathogenesis. Acta Chir Scand 1975; 141: 683–7.
9. Bremner CG, Lynch VP, Ellis FH Jr. Barrett's esophagus: congenital or acquired?; an experimental study of esophageal mucosal regeneration in the dog. Surgery 1970; 68: 209–16.
10. Hamilton SR, Yardley JH. Regeneration of cardiac type mucosa and acquisition of Barrett mucosa after esophagogastrostomy. Gastroenterology 1977; 72: 669–75.
11. Hamilton SR. Pathogenesis of columnar cell-lined (Barrett's) esophagus. In: Spechler SJ, Goyal RK, eds. Barrett's esophagus: pathophysiology, diagnosis, and management. New York: Elsevier Science, 1985:29–37.
12. Meyer W, Vollmar F, Bår W. Barrett-esophagus following total gastrectomy: a contribution to its pathogenesis. Endoscopy 1979; 11: 121–6.
13. Everhart CW Jr, Holtzapple PG, Humphries TJ. Barrett's esophagus: inherited epithelium or inherited reflux? J Clin Gastroenterol 1983; 5: 357–8.
14. Crabb DW, Berk MA, Hall TR, Conneally PM, Biege! AA. Lehman GA. Familial gastroesophageal reflux and development of Barrett's esophagus. Ann Intern Med 1985; 103: 52–4.
15. Smith RRL. Hamilton SR, Boitnott JK. Rogers EL. The spectrum of carcinoma arising in Barrett's esophagus: a clinicopathologic study of 26 patients. Am J Surg Pathol 1984; 8: 563–73.
16. Spechler SJ, Robbins AH, Rubins HB, et al. Adenocarcinoma and Barrett's esophagus: an overrated risk? Gastroenterology 1984; 87: 927–33.
17. Pauli A. Trier JS, Dalton MD, Camp RC, Loeb P, Goyal RK. The histologie spectrum of Barrett's esophagus. N Engl J Med 1976; 295: 476–80.
18. Trier JS. Morphology of the epithelium of the distal esophagus in patients with midesophageal peptic strictures. Gastroenterology 1970; 58: 444–61.
19. Berenson MM, Herbst JJ, Freston JW. Enzyme and ultrastructural characteristics of esophageal columnar epithelium. Am J Dig Dis 1974; 19: 895–907.
20. Levine DS, Rubin CE. Electron microscopic evidence for the gastric origin of Barrett's metaplasia and dysplasia. Gastroenterology 1986; 90: 1519. abstract.
21. Zwas F, Shields HM, Doos WG, et al. Scanning electron microscopy of Barrett's epithelium and its correlation with light microscopy and mucin stains. Gastroenterology 1986; 90: 1932–41.
22. Jass JR. Mucin histochemistry of the columnar epithelium of the oesophagus: a retrospective study. J Clin Pathol 1981; 34: 866–70.
23. Schreiber DS, Apstein M, Hermos JA. Paneth cells in Barrett's esophagus. Gastroenterology 1978; 74: 1302–4.
24. Banner BF, Memoli VA, Warren WH. Gould VE. Carcinoma with multidirectional differentiation arising in Barrett's esophagus. Ultrastruc Pathol 1983; 4: 205–17.
25. Dayal Y. Wolfe HJ. Endocrine cells in Barrett's epithelium. In: Spechler SJ, Goyal RK, eds. Barrett's esophagus: pathophysiology, diagnosis, and management. New York: Elsevier Science, 1985:59–73.
26. Buchan AMJ. Grant S, Freeman HJ. Regulatory peptides in Barrett's oesophagus. J Pathol 1985; 146: 227–34.
27. Jass JR. Role of intestinal metaplasia in the histogenesis of gastric carcinoma. J Clin Pathol 1980; 33: 801–10.
28. Mangla JC, Schenk EA, Desbaillets L, Guarasci G, Kubasik NP, Turner MD. Pepsin secretion, pepsinogen, and gastrin in “Barrett's esophagus”. Gastroenterology 1976; 70: 669–76.
29. Dahms BB, Rothstein FC. Barrett's esophagus in children: a consequence of chronic gastroesophageal reflux. Gastroenterology 1984; 86: 318–23.
30. Hassall E, Weinstein WM. Ament ME. Barrett's esophagus in childhood. Gastroenterology 1985; 89: 1331–7.
31. Thompson JJ, Zinsser KR, Enterline HT. Barrett's metaplasia and adenocarcinoma of the esophagus and gastroesophageal junction. Hum Pathol 1983; 14: 42–61.
32. Weinstein W, VanDeventer G, Ippoliti A. A histologie evaluation of Barrett's esophagus using a standardized endoscopic biopsy protocol. Gastroenterology 1984; 86: 1296. abstract.
33. Naef AP, Savary M, Ozzello L. Columnar-lined lower esophagus: an acquired lesion with malignant predisposition: report on 140 cases of Barrett's esophagus with 12 adenocarcinomas. J Thorac Cardiovasc Surg 1975; 70: 826–35.
34. Burbige EJ, Radigan JJ. Characteristics of the columnar-cell lined (Barrett's) esophagus. Gastrointest Endose 1979; 25: 133–6.
35. Schnell T, Sontag S, Wanner J, et al. endoscopic screening for Barrett's esophagus, esophageal adenocarcinoma and other mucosal changes in ambulatory subjects with symptomatic gastroesophageal reflux. Gastroenterology 1985; 88: 1576. abstract.
36. Sarr MG, Hamilton SR, Marrone GC, Cameron JL. Barrett's esophagus: its prevalence and association with adenocarcinoma in patients with symptoms of gastroesophageal reflux. Am J Surg 1985; 149: 187–93.
37. Starnes VA, Adkins RB, Ballinger JF, Sawyers JL. Barrett's esophagus: a surgical entity. Arch Surg 1984; 119: 563–7.
38. Spechler SJ, Sperber H, Doos WG, Schimmel EM. The prevalence of Barrett's esophagus in patients with chronic peptic esophageal strictures. Dig Dis Sci 1983; 28: 769–74.
39. Skinner DB, Walther BC, Riddell RH. Schmidt H, Iascone C, DeMeester TR. Barrett's esophagus: comparison of benign and malignant cases. Ann Surg 1983; 198: 554–66.
40. Haggitt RC, Dean PJ. Adenocarcinoma in Barrett's epithelium. In: Spechler SJ. Goyal RK, eds. Barrett's esophagus: pathophysiology, diagnosis, and management. New York: Elsevier Science, 1985:15366.
41. Burgess JN, Payne WS, Andersen HA, Weiland LH. Carlson HC. Barrett esophagus: the columnar-epithelial-lined lower esophagus. Mayo Clin Proc 1971; 46: 728–34.
42. Naef AP, Savary M. Conservative operations for peptic esophagitis with stenosis in columnar-lined lower esophagus. Ann Thorac Surg 1972; 13: 543–51.
43. Borrie J. Goldwater L. Columnar cell-lined esophagus: assessment of etiology and treatment: a 22 year experience. J Thorac Cardiova.sc Surg 1976; 71: 825–34.
44. Rosenberg JC, Budev H. Edwards RC, Singal S, Steiger Z. Sundareson AS. Analysis of adenocarcinoma in Barrett's esophagus utilizing a staging system. Cancer 1985; 55: 1353–60.
45. Bozymski EM, Herlihy KJ, Orlando RC. Barrett's esophagus. Ann Intern Med 1982; 97: 103–7.
46. Sjogren RW Jr, Johnson LF. Barrett's esophagus: a review. Am J Med 1983; 74: 313–21.
47. Iascone C, DeMeester TR, Little AG, Skinner DB. Barrett's esophagus: functional assessment, proposed pathogenesis, and surgical therapy. Arch Surg 1983; 118: 543–9.
48. Vincent ME, Robbins AH. Radiology of Barrett's esophagus. In: Spechler SJ, Goyal RK, eds. Barrett's esophagus: pathophysiology, diagnosis, and management. New York: Elsevier Science, 1985:91–104.
49. Chen YM, Gelfand DW, Ott DJ, Wu WC. Barrett esophagus as an extension of severe esophagitis: analysis of radiologic signs in 29 cases. AJR 1985; 145: 275–81.
50. Lackey C, Rankin RA. Welsh JD. Stricture location in Barrett's esophagus. Gastrointest Endose 1984; 30: 331–3.
51. Kothari T, Mangla JC, Kalra TMS. Barrett's ulcer and treatment with cimetidine. Arch Intern Med 1980; 140: 475–7.
52. Sanfey H, Hamilton SR, Smith RRL. Cameron JL. Carcinoma arising in Barrett's esophagus. Surg Gynecol Obstet 1985; 161: 570–4.
53. Harle IA, Finley RJ, Belsheim M, et al. Management of adenocarcinoma in columnar-lined esophagus. Ann Thorac Surg 1985; 40: 330–6.
54. Hawe A, Payne WS, Weiland LH, Fontana RS. Adenocarcinoma in the columnar epithelial lined lower (Barrett) oesophagus. Thorax 1973; 28: 511–4.
55. Messian RA, Hermos JA, Robbins AH, Friedlander DM, Schimmel EM. Barrett's esophagus: clinical review of 26 cases. Am J Gastroenterol 1978; 69: 458–66.
56. Bremner CG. Benign strictures of the esophagus. Curr Prob Surg 1982; 19: 402–89.
57. Menguy R. On the malignant potential of acquired short esophagus. Arch Surg 1979; 114: 260–3.
58. Ransom JM, Patel GK, Clift SA, Womble NE. Read RC. Extended and limited types of Barrett's esophagus in the adult. Ann Thorac Surg 1982; 33: 19–27.
59. Radigan LR, Glover JL, Shipley FE, Shoemaker RE. Barrett esophagus. Arch Surg 1977; 112: 486–91.
60. Cameron AJ, Ott BJ, Payne WS. The incidence of adenocarcinoma in columnar-lined (Barrett's) esophagus. N Engl J Med 1985; 313: 857–9.
61. Sprung DJ, Ellis FH Jr. Gibb SP. Incidence of adenocarcinoma in Barrett's esophagus. Am J Gastroenterol 1984; 79: 817. abstract.
62. Sontag SJ, Schnell TG, Chejfec G, et al. Barrett's oesophagus and colonie tumours. Lancet 1985; 1: 946–9.
63. Bosch A. Frias Z, Caldwell WL. Adenocarcinoma of the esophagus. Cancer 1979; 43: 1557–61.
64. Brookes VS. Waterhouse JAH, Powell DJ. Carcinoma of the stomach: a 10-year survey of results and of factors affecting prognosis. Br Med J 1965; 1: 1577–83.
65. Nelson PG. Dunlop E. Carcinoma of the cardia: a twenty-year study. Med J Aust 1970; 1: 152–5.
66. Fierst SM. Carcinoma of the cardia and fundus of the stomach. Am J Gastroenterol 1972; 57: 403–9.
67. Wang HH. Antonioli DA. Goldman H. Comparative features of esophageal and gastric adenocarcinomas: recent changes in type and frequency. Hum Pathol 1986; 17: 482–7.
68. MacDonald WC. Clinical and pathologic features of adenocarcinoma of the gastric cardia. Cancer 1972; 29: 724–32.
69. Kalish RJ, Clancy PE. Orringer MB. Appelman HD. Clinical, epidemiologic. and morphologic comparison between adenocarcinomas arising in Barrett's esophageal mucosa and in the gastric cardia. Gastroenterology 1984; 86: 461–7.
70. Danoff B, Cooper J, Klein M. Primary adenocarcinoma of the upper oesophagus. Clin Radiol 1978; 29: 519–22.
71. Skinner DB. The columnar-lined esophagus and adenocarcinoma. Ann Thorac Surg 1985; 40: 321–2.
72. Riddell RH. Goldman H. Ransohoff DF, et al. Dysplasia in inflammatory bowel disease: standardized classification with provisional clinical applications. Hum Pathol 1983; 14: 931–68.
73. Riddell RH. Dysplasia and regression in Barrett's epithelium. In: Spechler SJ, Goyal RK, eds. Barrett's esophagus: pathophysiology, diagnosis, and management. New York: Elsevier Science, 1985:143–52.
74. Reid BJ. Haggitt RC. Rubin CE, et al. Criteria for dysplasia in Barrett's esophagus: a cooperative consensus study. Gastroenterology 1985; 88: 1552. abstract.
75. Reid BJ. Haggitt RC. Rubin CE, Rabinovitch PS. Flow cytometry compliments histology in detecting patients at risk for Barrett's adenocarcinoma. Gastroenterology 1986; 90: 1600. abstract.
76. Schmidt HG, Riddell RH. Walther B, Skinner DB. Riemann JF. Dysplasia in Barrett's esophagus. Cancer Res Clin Oncol 1985; 110: 145–52.
77. Haggitt RC. Tryzelaar J. Ellis FH, Colcher H. Adenocarcinoma complicating columnar epithelium-lined (Barrett's) esophagus. Am J Clin Pathol 1978; 70: 1–5.
78. Herbst JJ, Berenson MM, McCloskey DW, Wiser WC. Cell proliferation in esophageal columnar epithelium (Barrett's esophagus). Gastroenterology 1978; 75: 683–7.
79. Lee RG. Dysplasia in Barrett's esophagus: a clinical pathologic study of six patients. Am J Surg Pathol 1985; 9: 845–52.
80. Reid BJ, Lewin K, VanDeventer G, et al. Barrett's esophagus: high-grade dysplasia and intramucosal carcinoma detected by endoscopic biopsy surveillance. Gastroenterology 1986; 90: 1601. abstract.
81. Levine MS. Kressel HY, Caroline DF, Laufer I. Herlinger H. Thompson JJ. Barrett esophagus: reticular pattern of the mucosa. Radiology 1983; 147: 663–7.
82. Vincent ME, Robbins AH, Spechler SJ, Schwartz R. Doos WG, Schimmel EM. The reticular pattern as a radiographic sign of the Barrett esophagus: an assessment. Radiology 1984; 153: 333–5.
83. Robbins AH, Vincent ME, Saini M, Schimmel EM. Revised radiologic concepts of the Barrett esophagus. Gastrointest Radiol 1978; 3: 377–81.
84. Agha FP. radiologic diagnosis of Barrett's esophagus: clinical analysis of 65 cases. Gastrointest Radiol 1986; 11: 123–30.
85. Holloway RH. Dodds WJ. Esophageal motor function in Barrett's esophagus. In: Spechler SJ, Goyal RK. eds. Barrett's esophagus: pathophysiology, diagnosis, and management. New York: Elsevier Science, 1985:10512.
86. Skinner DB, Walther BC. Little AG. Surgical treatment of Barrett's esophagus. In: Spechler SJ, Goyal RK, eds. Barrett's esophagus: pathophysiology. diagnosis, and management. New York: Elsevier Science, 1985:21121.
87. Mangla JC. Brown M. Diagnosis of Barrett's esophagus by pertechnetate radionuclide. Am J Dig Dis 1976; 21: 324–8.
88. Berquist TH. Nolan NG, Stephens DH. Carlson HC. Radioisotope scintigraphy in diagnosis of Barrett's esophagus. AJR 1975; 123: 401–11.
89. Vidins EI, Fox JAE, Beck IT. Transmural potential difference (PD) in the body of the esophagus in patients with esophagitis, Barrett's epithelium and carcinoma of the esophagus. Am J Dig Dis 1971; 16: 991–9.
90. Herlihy KJ. Orlando RC, Bryson JC, Bozymski EM, Carney CN, Powell DW. Barrett's esophagus: clinical, endoscopic, histologie, manometric, and electrical potential difference characteristics. Gastroenterology 1984; 86: 436–43.
91. Orlando RC. Transmural electrical potential difference measurements in Barrett's esophagus. In: Spechler SJ, Goyal RK, eds. Barrett's esophagus: pathophysiology. diagnosis, and management. New York: Elsevier Science, 1985:121–7.
92. Doos WG, Stilmant MS. Murphy JL. Robbins AH, Vincent ME, Spechler SJ. The cytologie characteristics of Barrett's epithelium. Gastroenterology 1985; 88: 1368. abstract.
93. Bozymski EM. Barrett's esophagus: endoscopic characteristics. In: Spechler SJ, Goyal RK, eds. Barrett's esophagus: pathophysiology, diagnosis, and manaaement. New York: Elsevier Science, 1985:113–9.
94. Castell DO. Medical management of the patient with Barrett's esophagus. In: Spechler SJ, Goyal RK, eds. Barrett's esophagus: pathophysiology, diagnosis, and management. New York: Elsevier Science, 1985:199–209.
95. Wesdorp ICE, Bartelsman J. Schipper MEI, Tytgat GN. Effect of long-term treatment with cimetidine and antacids in Barrett's oesophagus. Gut 1981; 22: 724–7.
96. Saltzman M, Barwick K, McCallum RW. Progression of cimetidine-treated reflux esophagitis to a Barrett's stricture. Dig Dis Sci 1982; 27: 181–6.
97. Humphries TJ. Long-term treatment and endoscopic follow-up of patients with Barrett's esophagus. Gastrointest Endose 1982; 28: 134. abstract.
98. Woodward ER. Surgical treatment of gastroesophageal reflux and its complications. World J Surg 1977; 1: 453–61.
99. Burnett HF, Read RC. Morris WD. Campbell GS. Management of complications of fundoplication and Barrett's esophagus. Surgery 1977; 82: 521–30.
100. Brand DL, Ylvisaker JT, Gelfand M, Pope CE II. Regression of columnar esophageal (Barrett's) epithelium after anti-reflux surgery. N Engl J Med 1980; 302: 844–8.
101. Hamilton SR, Hutcheon DF, Ravich WJ, Cameron JL. Paulson M. Adenocarcinoma in Barrett's esophagus after elimination of gastroesophageal reflux. Gastroenterology 1984; 86: 356–60.
102. Patel GK, Clift SA, Schaefer RA. Read RC, Texter EC Jr. Resolution of severe dysplastic changes with regression of columnar epithelium in Barrett's esophagus on medical treatment. Gastroenterology 1982; 82: 1147. abstract.
103. Sprung DJ, Ellis FH Jr, Gibb SP. Regression of Barrett's epithelium after anti-reflux surgery. Am J Gastroenterol 1984; 79: 817. abstract.
104. Pope CE IL Regression of Barrett's epithelium. In: Spechler SJ, Goyal RK. eds. Barrett's esophagus: pathophysiology. diagnosis, and management. New York: Elsevier Science, 1985:224–9.