Mechanism of cytotoxicity of anticancer platinum drugs: Evidence that cis-diamminedichloroplatinum(ii) and cis-diammine-(l,l-cyclobutanedicarboxylato)platinum(ii) differ only in the kinetics of their interaction with dna

Cancer Research

Volumn 46, Issue , 1986, Pages 1972-1979

  Knox, Richard J ^a   Friedlos, Frank ^a   Lydall, David A ^a   Roberts, John J ^a  

^a INSTITUTE OF CANCER RESEARCH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; CARBOPLATIN; CISPLATIN; RADIOISOTOPE;

1,1 CYCLOBUTANEDICARBOXYLIC ACID C 14; CARBOPLATIN C 14; CHEMICAL REACTION KINETICS; CYTOTOXICITY; DNA ADDUCT; DNA DAMAGE; DOSE RESPONSE; DOSE TIME EFFECT RELATION; DRUG ADMINISTRATION; DRUG BINDING; DRUG COMPARISON; DRUG CYTOTOXICITY; DRUG HALF LIFE; DRUG MECHANISM; DRUG RESPONSE; HUMAN; HUMAN CELL; INTOXICATION; PRELIMINARY COMMUNICATION; PRIORITY JOURNAL; WALKER CARCINOMA;

ANIMAL; ANTINEOPLASTIC AGENTS; CARBOPLATIN; CARCINOMA 256, WALKER; CELL SURVIVAL; CELLS, CULTURED; CISPLATIN; DNA; HUMAN; KINETICS; NUCLEIC ACID CONFORMATION; ORGANOPLATINUM COMPOUNDS; PLASMIDS; PLATINUM; SUPPORT, NON-U.S. GOV'T;

EID: 0022457418     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: None     Document Type: Article

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