Human multidrug-resistant cell lines: Increased mdr1 expression can precede gene amplification

Science

Volumn 232, Issue 4750, 1986, Pages 643-645

  Shen, D W ^a   Fojo, A ^a   Chin, J E ^b   Roninson, I B ^b   Richert, N ^a   Pastan, I ^a   Gottesman, M M ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b UNIVERSITY OF ILLINOIS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COLCHICINE; DOXORUBICIN; MESYLIC ACID ETHYL ESTER; VINBLASTINE;

BLOOD AND HEMOPOIETIC SYSTEM; CANCER CHEMOTHERAPY; CELL LINE; CHEMOTHERAPY; DRUG COMPARISON; DRUG RESISTANCE; DRUG SENSITIVITY; ENDOCRINE SYSTEM; FEMALE GENITAL SYSTEM; GENE AMPLIFICATION; GENETIC ENGINEERING; HEREDITY; HUMAN; LEUKEMIA; LEUKEMIA CELL; OVARY CARCINOMA; PRIORITY JOURNAL; SHORT SURVEY; THERAPY;

ANIMALS; CELL LINE; COLCHICINE; CRICETINAE; CRICETULUS; DNA, NEOPLASM; DOXORUBICIN; DRUG RESISTANCE; FEMALE; GENE AMPLIFICATION; HUMANS; LEUKEMIA, LYMPHOCYTIC; NEOPLASMS; NUCLEIC ACID HYBRIDIZATION; OVARIAN NEOPLASMS; RNA, MESSENGER; VINBLASTINE;

EID: 0022457103     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.3457471     Document Type: Article

References (0)