Single-dose pharmacokinetics of clomiphrene citrate in normal volunteers

Fertility and Sterility

Volumn 46, Issue 3, 1986, Pages 392-396

  Mikkelson, T J ^a   Kroboth, P D ^a   Cameron, W J ^a   Dittert, L W ^b   Chungi, V ^b   Manberg, P J ^b  

^a UNIVERSITY OF KANSAS   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

CLOMIFENE CITRATE;

CLINICAL TRIAL; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG DISTRIBUTION; DRUG FORMULATION; DRUG METABOLISM; HUMAN; HUMAN EXPERIMENT; INFERTILITY; METHODOLOGY; NORMAL HUMAN; ORAL DRUG ADMINISTRATION; OVULATION INDUCTION; PHARMACOKINETICS; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; UNITED STATES; VOLUNTEER;

EID: 0022449090     PISSN: 00150282     EISSN: None     Source Type: Journal    
DOI: 10.1016/s0015-0282(16)49574-9     Document Type: Article

References (11)

1. E.Y. Adashi Clomiphene citrate: mechanism(s) and site(s) of action—a hypothesis revisited Fertil Steril 42 1984 331
2. United States Pharmacopeia Revision XXI 1985 United States Pharmacopeial Convention Rockville, MD 231
3. L.C. Murphy R.L. Sutherland Antitumor activity of clomiphene analogs in vitro: relationship to affinity for estrogen receptor and another high affinity antiestrogen binding site J Clin Endocrinol Metab 57 1983 373
4. J.H. Clark B.M. Markaverich The agonistic-antiagonistic properties of clomiphene—a review Pharmacol Ther 15 1982 467
5. J. Van Campenhout E.T. Borreman H. Wyman A. Antaki Induction of ovulation with cisclomiphene Am J Obstet Gynecol 15 1973 321
6. 14C labeled clomiphene citrate Clin Res 14 1966 287
7. Baustian CL, Mikkelson TJ: Human plasma analysis of clomiphene isomers and detection of metabolites using reversed phase chromatography and fluorescence detection. J Pharmacol Biomed Analysis. In press
8. T.J. Mikkelson C.L. Baustian W.J. Cameron Preliminary report of the disposition of clomiphene in healthy human subjects (Abstr) Fertil Steril 41 1984 935
9. J.O. Kim F.H. Kohout Analysis of variance covariance: subprograms ANOVA and ONEWAY N.H. Nie C.H. Hull J.G. Jenkins K. Steinbremer D. Bent SPSS. Statistical Package for the Social Sciences, SPSS, Inc. 1975 (Software) 1975 McGraw-Hill Book Company New York
10. R. Jennrick P. Sampson J. Frane P2V: analysis of variance and covariance including repeated measures W.J. Dixon C.A. Berkeley BMDP Statistical Software 1983 University of California Press
11. Mikkelson TJ, Cameron WJ, Chungi V, Manberg PJ: Unpublished data