Inactivation of rat hepatic cytochrome P-450 by spironolactone

Biochemical and Biophysical Research Communications

Volumn 136, Issue 3, 1986, Pages 1162-1169

  Decker, Caroline ^a   Sugiyama, Katsumi ^a   Underwood, Marilyn ^a   Correia, Maria Almira ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME P450; DEXAMETHASONE; SPIRONOLACTONE;

ANIMAL CELL; DRUG EFFICACY; DRUG TOXICITY; ENZYME INACTIVATION; ENZYME INHIBITION; INTOXICATION; LIVER; LIVER MICROSOME; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMAL; CYTOCHROME P-450 ENZYME SYSTEM; DEXAMETHASONE; DRUG SYNERGISM; HEME; MALE; MICROSOMES, LIVER; NADP; RATS; RATS, INBRED STRAINS; SPIRONOLACTONE; SUPPORT, U.S. GOV'T, P.H.S.; TIME FACTORS; TROLEANDOMYCIN;

EID: 0022448252     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/0006-291X(86)90456-0     Document Type: Article

References (28)

1. Apocytochrome P-450: reconstitution of functional cytochrome with hemin in vitro.
2. Destruction of cytochrome P-450 by allylisopropylacetamide is a suicidal process