Opioid, cholinergic and α-adrenergic influences on the modulation of nociception from the lateral reticular nucleus of the rat

Brain Research

Volumn 384, Issue 2, 1986, Pages 282-293

  Ossipov, M H ^a   Gebhart, G F ^a  

^a UNIVERSITY OF IOWA   (United States)

Author keywords

Antinociception; Cholinergic; Descending inhibition; Hot plate test; Lateral reticular nucleus; opioid; Tail flick reflex; Adrenergic

Indexed keywords

ALPHA ADRENERGIC RECEPTOR; CARBACHOL; CHOLINERGIC RECEPTOR STIMULATING AGENT; MORPHINE; NALOXONE; NORADRENALIN; OPIATE; PHENYLEPHRINE;

ANIMAL EXPERIMENT; CENTRAL NERVOUS SYSTEM; DRUG EFFICACY; DRUG INTERACTION; INTRACEREBRAL DRUG ADMINISTRATION; LATERAL RETICULAR NUCLEUS; NOCICEPTION; NONHUMAN; PAIN; PERIPHERAL NERVOUS SYSTEM; PRIORITY JOURNAL; RAT;

ADRENERGIC FIBERS; ANIMAL; BRAIN MAPPING; CHOLINERGIC FIBERS; ENDORPHINS; MALE; MEDULLA OBLONGATA; NEUROTRANSMITTERS; PAIN; RATS; RATS, INBRED STRAINS; RETICULAR FORMATION; SUPPORT, U.S. GOV'T, P.H.S.; SYNAPTIC TRANSMISSION;

EID: 0022445055     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/0006-8993(86)91164-9     Document Type: Article

References (38)

1. Hypoalgesia induced by local injection of carbachol into the nucleus raphe magnus
2. Cholinergic and serotonergic systems in the brain and spinal cord: anatomic organization, role in intercellular communication processes, and interactive mechanisms
3. Alpha-2 adrenergic receptors on neurons in the region of the lateral reticular nucleus of the rat
4. The lateral reticular nucleus in the cat. II. Organization of component activated from bilateral ventral flexor reflex tract (bVFRT)
5. The lateral nucleus in the cat. I. An experimental anatomical study of its spinal and supraspinal afferent connections
6. The lateral reticular nucleus in the cat. II. Effects of lateral reticular lesions on posture and reflex movements
7. The reticulocerebellar projection to the pyramis and copula pyramidis in the rat: an experimental study using retrograde transport of horseradish peroxidase
8. A reinvestigation of the analgesic effects induced by stimulation of the periaqueductal gray matter in the rat. I. The production of behavioral side-effects together with analgesia
9. A reinvestigation of the analgesic effects induced by stimulation of the periaqueductal gray matter in the rat. II. Differential characteristics of the analgesia induced by ventral and dorsal PAG stimulation
10. Inhibition of spinal nociceptive information by stimulation in midbrain of the cat is blocked by lidocaine microinjected in nucleus raphe magnus and medullary reticular formation
11. Characterization of inhibition of the spinal nociceptive tail-flick reflex in the rat from the medullary lateral reticular nucleus
12. The location of brainstem neurons tonically inhibiting dorsal horn neurons of the cat
13. Behavioral evidence for a cholinoceptive pontine inhibitory area: descending control of spinal motor output and sensory input
14. Non-opiate analgesia induced by carbachol microinjection into the pontine parabrachial region of the cat
15. Evidence for involvement of cholinoceptive cells of the parabrachial region in environmentally induced nociceptive suppression in the cat
16. Ventrolateral medullary lesions block the antinociceptive and cardiovascular responses elicited by stimulating the dorsal periaqueductal grey matter in rats
17. Spinal neurons reaching the lateral reticular nucleus as studied in the rat by retrograde transport of horseradish peroxidase
18. The effects of lesions of medullary midline and lateral reticular areas on inhibition in the dorsal horn produced by periaqueductal grey stimulation in the cat
19. Lateral reticular regions and the descending control of dorsal horn neurons of the cat: selective inhibition by electrical stimulation
20. Opiod, cholinergic, and α adrenergic input modulation of descending inhibition from the lateral reticular nucleus (LRN)
21. Light pentobarbital anesthesia diminishes the antinociceptive potency of morphine administered intracranially but not intrathecally in the rat
22. Topographic atlas of catecholamine and acetylcholine-containing neurons in the rat brain. I. Hindbrain (mesencephalon, rhombencephalon)
23. Projections to the caudolateral medulla from the pons midbrain and diencephalon in the cat
24. Projection from the periaqueductal gray to the lateral reticular nucleus in the cat
25. Characterization of inhibition of a spinal nociceptive reflex by stimulation medially and literally in the midbrain and medulla in the lightly pentobarbital-anesthetized rat
26. Relative contributions of the nucleus raphe magnus and adjacent medullary reticular formation to the inhibition by stimulation in the periaqueductal gray of a spinal nociceptive reflex in the pentobarbita-anesthetized rat
27. A comparison of the distribution of central cholinergic neurons as demonstrated by acetylcholinesterase pharmacohistochemistry and choline acetyltransferase immunohistochemistry
28. Immunohistochemical mapping of enkephalin-containing cell bodies, fibers and nerve terminals in the brain of the rat
29. The lateral reticular nucleus of the medulla oblongata in mammals. A comparative anatomical study
30. Muscarinic cholinergic mediation of opiate and non-opiate environmentally induced analgesias
31. Facilitation of spinal motoneuron excitability by 5-hydroxytryptamine and noradrenaline
32. Hypertensive response following stimulation of opiate receptors in the caudal ventrolateral medulla
33. Cardiovascular control by cholinergic mechanisms in the rostral ventrolateral medulla
34. Pharmacology of spinal adrenergic systems which modulate spinal nociceptive processing
35. Narcotic analgesics: CNS sites and mechanisms of action as revealed by intracerebral injection techniques