Comparison of T Antigen Expression in Normal, Premalignant, and Malignant Human Colonic Tissue Using Lectin and Antibody Immunohistochemistry

Cancer Research

Volumn 46, Issue 9, 1986, Pages 4841-4847

  Trump, Benjamin F ^e   Tomita, Joseph T ^b   Boland, C Richard ^a   Kim, Young S ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b ABBOTT LABORATORIES   (United States)

^c Shady Side Academy   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MONOCLONAL ANTIBODY; PEANUT AGGLUTININ; THOMSEN FRIEDENREICH ANTIGEN; TUMOR ANTIGEN; UNCLASSIFIED DRUG;

ADENOMATOUS POLYP; ARTICLE; COLON CANCER; CYTOLOGY; HUMAN; HUMAN CELL; LARGE INTESTINE; LECTIN BINDING; PRIORITY JOURNAL; SENSITIVITY; SPECIFICITY;

ADENOMA; ANTIBODIES, MONOCLONAL; ANTIGENS, NEOPLASM; ANTIGENS, TUMOR-ASSOCIATED, CARBOHYDRATE; BLOOD GROUP ANTIGENS; CELL DIFFERENTIATION; COLON; COLONIC NEOPLASMS; DISACCHARIDES; HUMANS; HYPERPLASIA; INTESTINAL MUCOSA; INTESTINAL POLYPS; LECTINS; OLIGOSACCHARIDES; PEANUT AGGLUTININ; PRECANCEROUS CONDITIONS; RECTAL NEOPLASMS; RECTUM;

EID: 0022442421     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: None     Document Type: Article

References (27)

1. Kuhns, W. J. Blood group alterations in cancer. Contemp. Hematol. Oncol., 1: 149-200, 1980.
2. Hakomori, S., and Kannagi, R. Glycosphingolipids as tumor-associated and differentiation markers. J. Natl. Cancer Inst., 71: 231-251, 1983.
3. Yuan, M., Itzkowitz, S. H., Palekar, A., Shamsuddin, A. M., Phelps, P. C., Trump, B. F., and Kim, Y. S. Distribution of blood group antigens A, B, H, Lewisa, and Lewisb in human normal, fetal, and malignant colonic tissue. Cancer Res., 45: 4499-4511, 1985.
4. Springer, G. F., Desai, P. R., Murthy, M. S., Tegtmeyer, H., and Scanlon, E. F. Human carcinoma-associated precursor antigens of the blood group MN system and the hosts's immune responses to them. Prog. Allergy, 26: 42-96, 1979.
5. Lotan, R., Skutelsky, E., Danon, D., and Sharon, N. The purification, composition, and specificity of the anti-T lectin from peanut (Arachis hypogaea). J. Biol. Chem., 250: 8518-8523, 1975.
6. Boland, C. R., Montgomery, C. K., and Kim, Y. S. Alterations in human colonic mucin occurring with cellular differentiation and malignant transformation. Proc. Natl. Acad. Sci. USA, 79: 2051-2055, 1982.
7. Boland, C. R., Montgomery, C. K., and Kim, Y. S. A cancer-associated mucin alteration in benign colonic polyps. Gastroenterology, 82: 664-672, 1982.
8. Cooper, H. S. Peanut lectin-binding sites in large bowel carcinoma. Lab. Invest., 47: 383-390, 1982.
9. Cooper, H. S., and Reuter, V. E. Peanut lectin-binding sites in polyps of the colon and rectum: adenomas, hyperplastic polyps, and adenomas with in situ carcinoma. Lab. Invest., 49: 655-661, 1983.
10. Orntoft, T. F., Mors, N. P. O., Eriksen, G., Jacobsen, N. O., and Poulsen, H. S. Comparative immunoperoxidase demonstration of T Antigens in human colorectal carcinomas and morphologically abnormal mucosa. Cancer Res., 45: 447-452, 1985.
11. Klein, P. J., Osmers, R., Vierbuchen, M., Ortmann, M., Kania, J., and Uhlenbruck, G. The importance of lectin binding sites and carcinoembryonic antigen with regard to normal, hyperplastic, adenomatous, and carcinomatous colonic mucosa. Recent Results Cancer Res., 79: 1-9, 1981.
12. Springer, G. F., Murthy, S. M., Desai, P. R., Fry, W. A., Tegtmeyer, H., and Scanlon, E. F. Patient's immune response to breast and lung carcinoma-associated Thomsen-Friedenreich (T) specificity. Klin. Wochenschr., 60: 121-131, 1982.
13. Rahman, A. F. R., and Longenecker, B. M. A monoclonal antibody specific for the Thomsen-Friedenreich cryptic T antigen. J. Immunol., 129: 2021-2024, 1982.
14. Konishi, F., and Morson, B. C. Pathology of colorectal adenomas: a colonoscopic survey. J. Clin. Pathol., 35: 830-841, 1982.
15. Kim, Y. D. Immunochemical characteristics of human anti-T antibodies. Vox Sang., 39: 162-168, 1980.
16. Lisowska, E., and Kordowicz, M. Specific antibodies for desialized M and N blood group antigens. Vox Sang., 33: 164-169, 1977.
17. Muto, T., Bussey, H. J. R., and Morson, B. C. The evolution of cancer of the colon and rectum. Cancer (Phila.), 36: 2251-2270, 1975.
18. Coon, J. S., Weinstein, R. S., and Summers, J. L. Blood group precursor Tantigen expression in human urinary bladder carcinoma. Am. J. Clin. Pathol., 77: 692-699, 1982.
19. Bray, J., Maclean, G. D., Dusel, F. J., and McPherson, T. A. Decreased levels of circulating lytic anti-T in the serum of patients with metastatic gastrointestinal cancer: a correlation with disease burden. Clin. Exp. Immunol., 47: 176-182, 1982.
20. Lane, N., Kaplan, H., and Pascal, R. P. Minute adenomatous and hyperplastic polyps of the colon. Divergent patterns of epithelial growth with specific associated mesenchymal changes. Gastroenterology, 60: 537-551, 1971.
21. Fenoglio, C. M., and Lane, N. The anatomic precursor of colorectal carcinoma. Cancer (Phila.), 34: 819-923, 1974.
22. Cooper, H. S. Lectins as probes in histochemistry and immunohistochemistry: the peanut (Arachis hypogaea) lectin. Hum. Pathol., 15: 904-906, 1984.
23. Boland, C. R., Lance, P., Levin, B., Riddell, R. H., and Kim, Y. S. Abnormal goblet cell glycoconjugates in rectal biopsies associated with an increased risk of neoplasia in patients with ulcerative colitis: early results of a prospective study. Gut, 25: 1364-1371, 1984.
24. Kim, Y. S., Isaacs, R., and Perdomo, J. M. Alterations of membrane glycopeptides in human colonic adenocarcinoma. Proc. Natl. Acad. Sci. USA, 71: 4869-4873, 1974.
25. Stellner, K., Hakomori, S., and Warner, G. A. Enzymic conversion of “H-glycolipid” to A or B glycolipid and deficiency of these enzyme activities in adenocarcinoma. Biochem. Biophys. Res. Commun., 55: 439-445, 1973.
26. Kim, Y. S., and Itzkowitz, S. H. Reply to Letter to the Editor. Cancer Res., 45:913, 1985.
27. Sadler, J. E., Paulson, J. C., and Hill, R. L. The role of sialic acid in the expression of human MN blood group antigens. J. Biol. Chem., 254: 2112-2119, 1979.