Mode of Interaction of β-Hydroxy-β-methylglutaryl Coenzyme A Reductase with Strong Binding Inhibitors: Compactin and Related Compounds

Biochemistry

Volumn 24, Issue 6, 1985, Pages 1364-1376

  Nakamura, Charles E ^a   Abeles, Robert H ^a  

^a BRANDEIS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3 HYDROXY 3 METHYLGLUTARYL COENZYME A; 3-HYDROXY-3-METHYLGLUTARYL-COENZYME A; 6 (2 (2,4 DICHLORO 6 HYDROXYPHENYL)ETHYL) 3,4,5,6 TETRAHYDRO 4 HYDROXY 2H PYRAN 2 ONE; 6-(2-(2,4-DICHLORO-6-HYDROXYPHENYL)ETHYL)-3,4,5,6-TETRAHYDRO-4-HYDROXY-2H-PYRAN-2-ONE; ACYL COENZYME A; COENZYME A; COMPACTIN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE; NAPHTHALENE DERIVATIVE; NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; PYRAN DERIVATIVE; PYRONE DERIVATIVE;

ARTICLE; ENZYMOLOGY; KINETICS; MATHEMATICS; METABOLISM; SACCHAROMYCES CEREVISIAE;

ACYL COENZYME A; COENZYME A; HYDROXYMETHYLGLUTARYL COA REDUCTASES; KINETICS; MATHEMATICS; NADP; NAPHTHALENES; PYRANS; PYRONES; SACCHAROMYCES CEREVISIAE; SUPPORT, U.S. GOV'T, P.H.S.;

EID: 0022423907     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi00327a014     Document Type: Article

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