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Volumn 41, Issue 12, 1985, Pages 1576-1577

TRH analogue with C-terminal thioamide group. Synthesis, receptor binding, TSH-releasing activity and α-MSH-releasing activity

Author keywords

MSH releasing activity; Prot3 TRH; receptor binding affinity; thiopeptide; TSH releasing activity

Indexed keywords

ALPHA INTERMEDIN; PROTIRELIN; PROTIRELIN DERIVATIVE; PROTIRELIN RECEPTOR; PROTIRELIN[3 (2 PYRROLIDINECARBOTHIOAMIDE)]; THYROTROPIN; UNCLASSIFIED DRUG;

EID: 0022404893     PISSN: 00144754     EISSN: 14209071     Source Type: Journal    
DOI: 10.1007/BF01964815     Document Type: Article
Times cited : (16)

References (14)
  • 8
    • 84933837434 scopus 로고    scopus 로고
    • Abbreviations: The symbols for the amino acids and peptides are in accordance with the Recommendations 1983 of the IUPAC-IUB Joint Commission on Biochemical Nomenclature (Eur. J. Biochem. 138 (1984) 9). DCC — dicyclohexylcarbodiimide, DNP — 2,4-dinitrophenyl, MA — mixed anhydride with isobutyl chloroformate, OTcp —2,4,5-trichlorophenyl, TFA — trifluoroacetic acid, HOBt — N-hydroxybenzotriazole, LR — 2,4-bis-(4-methoxyphenyl)-1,3,2,4-dithiadiphosphetane-2,4-disulfide (Lawesson's Reagent), IC50 — the concentration of drug inhibiting specific binding by 50%.
  • 13
    • 84933837437 scopus 로고    scopus 로고
    • Alexandrova, M., Przybylski, J., Kruszyński, M., Tonon, M.C., Vaudry, H., Zboińska, J., and Kupryszewski, G., Pol. J. Pharmac. Pharm., in press.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.