Clavalanine (Ro 22–5417), a New Clavam Antibiotic from Streptomyces clavuligerus. 4. A Stereorational Synthesis

Journal of Organic Chemistry

Volumn 50, Issue 19, 1985, Pages 3457-3462

  Bernardo, Silvano De ^a   Tengi, John P ^a   Sasso, Gino J ^a   Weigele, Manfred ^a  

^a HOFFMANN LA ROCHE INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CLAVALANINE; NEW DRUG; UNCLASSIFIED DRUG;

CLAVALANINE; DRUG STRUCTURE; DRUG SYNTHESIS; INFRARED SPECTROMETRY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; THEORETICAL STUDY;

EID: 0022394141     PISSN: 00223263     EISSN: 15206904     Source Type: Journal    
DOI: 10.1021/jo00219a008     Document Type: Article

References (6)

1. Reading, C; Cole, M. Antimicrob. Agents Chemother. 1977, 11, 852 and references therein.
2. Pruess, D. L.; Kellett, M. J. Antibiot. 1983, 36, 208.
3. Evans, R. H.; Ax, H.; Jacoby, A.; Williams, T. H.; Jenkins, E.; Scannell, J. J. Antibiot. 1983, 36, 213.
4. Muller, J. C.; Toome, V.; Pruess, D. L.; Blount, J. F.; Weigele, M. J. Antibiot. 1983, 36, 217. Barton, D. H. R.; McCombie, S. W. J. Chem. Soc. Perkin Trans. 1 1975, 1574.
5. Wagner, D.; Verheyden, J. P. H.; Moffatt, J. G. J. Org. Chem. 1974, 39, 24. Clauss, K.; Grimm, D.; Prossel, G. Liebigs Ann. Chem. 1974, 539.
6. Rehling, H.; Jensen, H. Tetrahedron Lett. 1972, 2793.