Strategies to reduce the cost of mutagenicity screening with the Salmonella assay

Environmental Mutagenesis

Volumn 7, Issue 6, 1985, Pages 901-911

  Zeiger, Errol ^a   Risko, Kenneth J ^a   Margolin, Barry H ^a  

^a NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

Author keywords

Ames test; mutagens; Salmonella; sequential screening strategy

Indexed keywords

AMES TEST; DIAGNOSIS; ECONOMIC ASPECT; HEREDITY; METHODOLOGY; MUTAGEN TESTING; NONHUMAN; SALMONELLA; SCREENING;

ANIMAL; BIOTRANSFORMATION; COSTS AND COST ANALYSIS; HAMSTERS; MALE; MICROSOMES, LIVER; MUTAGENICITY TESTS; RATS; SALMONELLA TYPHIMURIUM;

EID: 0022380231     PISSN: 01922521     EISSN: 1930238X     Source Type: Journal    
DOI: 10.1002/em.2860070611     Document Type: Article

References (9)

1. Methods for detecting carcinogens and mutagens with the Salmonella/mammalian‐microsome mutagenicity test
2. Salmonella mutagenicity test results for 250 chemicals
3. Preliminary results of an international survey on sensitivity of S. typhimurium strains in the Ames test
4. A new Salmonella tester strain for the detection of frameshift mutagens: A run of cytosines as a mutational hot‐spot
5. A new Salmonella tester strain (TA102) with A:T base‐pairs at the site of mutation detects oxidative mutagens
6. Statistical analysis of the Ames Salmonella/microsome test
7. Revised methods for the Salmonella mutagenicity test
8. An overview of genetic toxicity testing in the National Toxicology Program
9. Tests with a preincubation modification of the Salmonella/microsome assay