Fungal metabolism and detoxification of polycyclic aromatic hydrocarbons

Archives of Microbiology

Volumn 143, Issue 2, 1985, Pages 105-110

  Cerniglia, Carl E ^a   White, Gail L ^a   Heflich, Robert H ^a  

^a NATIONAL CENTER FOR TOXICOLOGICAL RESEARCH   (United States)

Author keywords

Biotransformation; Cunninghamella elegans; Detoxification; Fungi; Mutagenicity; Polycyclic aromatic hydrocarbons; Salmonella reversion assay

Indexed keywords

POLYCYCLIC AROMATIC HYDROCARBON;

BIOTRANSFORMATION; FUNGUS; HEREDITY; METABOLISM; MUTAGENICITY; NONHUMAN; PRIORITY JOURNAL;

ANIMAL; BIOTRANSFORMATION; COMPARATIVE STUDY; MICROSOMES, LIVER; MUCORALES; MUTAGENICITY TESTS; MUTAGENS; MUTATION; POLYCYCLIC HYDROCARBONS; RATS; SALMONELLA TYPHIMURIUM; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0022374365     PISSN: 03028933     EISSN: 1432072X     Source Type: Journal    
DOI: 10.1007/BF00411031     Document Type: Article

References (28)

1. Methods for detecting carcinogens and mutagens with the Salmonella/mammalian-microsome mutagenicity test
2. Polycyclic aromatic compounds in nature
3. Mutagenicity of phenanthrene and phenanthrene K-region derivatives
4. Aromatic hydrocarbons: Metabolism by bacteria, fungi, and algae
5. Microbial metabolism of polycyclic aromatic hydrocarbons
6. Metabolism of naphthalene by Cunninghamella elegans
7. Oxidation of benzo[a]pyrene by the filamentous fungus Cunninghamella elegans
8. Fungal oxidation of benzo[a]pyrene and (±)- trans-7,8-dihydroxy-7,8-dihydrobenzo[a]pyrene; Evidence for the formation of benzo[a]pyrene 7,8-diol-9,10-epoxide
9. Fungal oxidation of (±)-9,10-dihydroxy-9,10-dihydrobenzo[a]pyrene: Formation of diasteromeric benzo[a]pyrene 9,10-diol-7,8-epoxides
10. Stereoselective metabolism of anthracene and phenanthrene by the fungus Cunninghamella elegans
11. Studies on the fungal oxidation of polycyclic aromatic hydrocarbons
12. Fungal oxidation of 3-methylcholanthrene: Formation of proximate carcinogenic metabolites of 3-methylcholanthrene
13. Glucuronide and sulfate conjugation in the fungal metabolism of aromatic hydrocarbons
14. Effects of a fluoro substituent on the fungal metabolism of 1-fluoronaphthalene
15. The mitiation of tumors on mouse skin by dihydrodiols derived from 7,12-dimethylbenz[a]anthracene and 3-methylcholanthrene
16. Polynuclear aromatic carcinogens
17. Rates of microbial transformation of polycyclic aromatic hydrocarbons in water and sediments in the vicinity of a coal-coking wastewater discharge
18. Microbial transformation of polycyclic aromatic hydrocarbons in pristine and petroleumcontaminated sediments
19. Identification of mutagenic metabolites in mammalian cells
20. Revised methods for the Salmonella mutagenicity test
21. Involvement of dihydrodiols and diol epoxides in the metabolic activation of polycyclic hydrocarbons other than benzo[a]pyrene
22. Carcinogenicity and mutagenicity of the 3,4-dihydrodiols and other metabolites of 7,12-dimethylbenz[a]anthracene and its hydroxymethyl derivatives
23. Differences in mutagenicity of the optical enantiomers of the diasteromeric benzo[a]pyrene 7,8-diol-9,10-epoxides
24. Metabolic activation of 3-methylcholanthrene and its metabolites to products mutagenic to bacterial and mammalian cells
25. Mutagenicity of the enantiomers of the diasteromeric bay-region benz[a]anthracene 3,4-diol-1,2-epoxides in bacterial and mammalian cells