Molecular mechanisms of receptor desensitization using the β-adrenergic receptor-coupled adenylate cyclase system as a model

Nature

Volumn 317, Issue 6033, 1985, Pages 124-129

  Sibley, David R ^a   Lefkowitz, Robert J ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENYLATE CYCLASE; BETA ADRENERGIC RECEPTOR; CATECHOLAMINE; ISOPRENALINE; PROSTAGLANDIN E1; RADIOISOTOPE;

4 (3 TERT BUTYLAMINO 2 HYDROXYPROPOXY) 2 BENZIMIDAZOLONE H 3; ANIMAL CELL; BIOLOGICAL MODEL; BIRD; BLOOD AND HEMOPOIETIC SYSTEM; DIHYDROALPRENOLOL H 3; DOSE RESPONSE; DRUG ANTAGONISM; DRUG COMPARISON; DRUG RECEPTOR BINDING; DRUG RESPONSE; DRUG SENSITIVITY; HEREDITY; HUMAN; HUMAN CELL; IN VITRO STUDY; NERVOUS SYSTEM; NICOTINAMIDE ADENINE DINUCLEOTIDE P 32; PHARMACOKINETICS; PRIORITY JOURNAL; RAT; RESPIRATORY SYSTEM; REVIEW; S49 CELL;

ADAPTATION, PHYSIOLOGICAL; ADENYLATE CYCLASE; ANIMAL; CELL MEMBRANE; CELLS, CULTURED; FIBROBLASTS; GTP-BINDING PROTEINS; HORMONES; HUMAN; MODELS, BIOLOGICAL; PHOSPHORYLATION; RECEPTORS, ADRENERGIC, BETA; SUPPORT, U.S. GOV'T, P.H.S.; VIRAL NONSTRUCTURAL PROTEINS; VIRAL PROTEINS;

EID: 0022374275     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/317124a0     Document Type: Article

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