A new method for assessment of drug disposition in muscle: Application of statistical moment theory to local perfusion systems

Journal of Pharmacokinetics and Biopharmaceutics

Volumn 13, Issue 6, 1985, Pages 609-631

  Kakutani, Toshiyuki ^a   Yamaoka, Kiyoshi ^a   Hashida, Mitsuru ^a   Sezaki, Hitoshi ^a  

^a KYOTO UNIVERSITY   (Japan)

Author keywords

dispersion ratio; drug disposition; lipophilic derivative; local perfusion system; mean elimination time; mitomycin C; rabbit muscle tissue; statistical moment theory; tissue distribution ratio

Indexed keywords

MITOMYCIN C;

1A NONYLOXYCARBONYLMITOMYCIN C; ANIMAL EXPERIMENT; DRUG ANALYSIS; DRUG DETERMINATION; DRUG DISTRIBUTION; DRUG ELIMINATION; DRUG TISSUE LEVEL; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; METHODOLOGY; MUSCLE; NONHUMAN; PRIORITY JOURNAL; RABBIT; REGIONAL PERFUSION; SPECTROMETRY; STATISTICAL MOMENTS THEORY; THEORETICAL STUDY;

ANIMAL; KINETICS; MALE; MITOMYCIN; MITOMYCINS; MODELS, BIOLOGICAL; MUSCLES; PERFUSION; PHARMACEUTICAL PREPARATIONS; RABBITS; STATISTICS; TISSUE DISTRIBUTION;

EID: 0022369121     PISSN: 0090466X     EISSN: 15738744     Source Type: Journal    
DOI: 10.1007/BF01058904     Document Type: Article

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