Sites of the neurotoxic action of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in the macaque monkey include the ventral tegmental area and the locus coeruleus

Neuroscience Letters

Volumn 61, Issue 1-2, 1985, Pages 195-200

  Mitchell, I J ^a   Cross, A J ^a   Sambrook, M A ^a   Crossman, A R ^a  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

1 methyl 4 phenyl 1,2,3,6 tetrahydropyridine; dopamine; locus coeruleus; macaque monkey; MPTP; noradrenaline; Parkinson's disease; ventral tegmental area

Indexed keywords

1,2,3,6 TETRAHYDRO 1 METHYL 4 PHENYLPYRIDINE; BENSERAZIDE; BENSERAZIDE PLUS LEVODOPA; CARBIDOPA; CARBIDOPA PLUS LEVODOPA; DOPAMINE; LEVODOPA;

ANIMAL CELL; ANIMAL EXPERIMENT; CENTRAL NERVOUS SYSTEM; CYTOLOGY; DRUG COMPARISON; DRUG DOSE; DRUG EFFICACY; DRUG MONITORING; DRUG THERAPY; ETIOLOGY; INTOXICATION; INTRAVENOUS DRUG ADMINISTRATION; LOCUS CERULEUS; MONKEY; NERVOUS SYSTEM; NEUROTOXICITY; NONHUMAN; PARKINSONISM; PRELIMINARY COMMUNICATION; PRIORITY JOURNAL; THERAPY; VENTRAL TEGMENTUM;

1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE; ANIMAL; BRAIN CHEMISTRY; CATECHOLAMINES; FEMALE; LOCUS COERULEUS; MACACA FASCICULARIS; PARKINSON DISEASE, SECONDARY; PYRIDINES; SUPPORT, NON-U.S. GOV'T; TEGMENTUM MESENCEPHALI;

EID: 0022350722     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/0304-3940(85)90424-0     Document Type: Article

References (10)

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8. Is the mesocortical dopaminergic system involved in Parkinson's disease?
9. 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced parkinsonism in the common marmoset
10. Parkinsonism induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP): implication for treatment and pathogenesis of Parkinson's disease