Effects of diadenosine triphosphate (Ap3A) and diadenosine tetraphosphate (Ap4A) on platelet aggregation in unfractionated human blood

Blut

Volumn 51, Issue 6, 1985, Pages 405-413

  Lüthje, Jürgen ^a   Baringer, Johann ^a   Ogilvie, Adaling ^a  

^a UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

Author keywords

Ap3A; Ap4A; Blood; Diadenosine tetraphosphate; Diadenosine triphosphate; Platelet aggregation

Indexed keywords

ADENOSINE DIPHOSPHATE; DIADENOSINE TETRAPHOSPHATE; DIADENOSINE TRIPHOSPHATE;

BLOOD AND HEMOPOIETIC SYSTEM; DOSE RESPONSE; DOSE TIME EFFECT RELATION; DRUG COMPARISON; DRUG MECHANISM; DRUG RESPONSE; HUMAN; HUMAN CELL; PRIORITY JOURNAL;

ADENINE NUCLEOTIDES; ADENOSINE DIPHOSPHATE; DOSE-RESPONSE RELATIONSHIP, DRUG; HEPARIN; HUMAN; KINETICS; PLATELET AGGREGATION; PLATELET COUNT; SUPPORT, NON-U.S. GOV'T;

EID: 0022346242     PISSN: 00065242     EISSN: 14320584     Source Type: Journal    
DOI: 10.1007/BF00320727     Document Type: Article

References (17)

1. Hemodynamic and platelet response to the bolus intravenous administration of porcine heparin
2. Inhibition of platelet aggregation by Ap4A
3. Abundant amounts of diadenosine 5′, 5‴-P1, P4-tetraphosphate are present and releasable but metabolically inactive, in human platelets
4. Inhibition of platelet aggregation and the platelet release reaction by α, ω diadenosine polyphosphates
5. The presence of diadenosine 5′, 5‴-P1, P3-triphosphate (Ap3A) in human platelets
6. Diadenosine triphosphate (Ap3A) mediates human platelet aggregation by liberation of ADP
7. Isolation and partial characterization of diadenosine triphosphatase from human plasma — a potential factor of hemostasis
8. Catabolism of Ap3A and Ap4A in human plasma: purification and characterization of a glycoprotein complex with 5′-nucleotide phosphodiesterase activity
9. Highly efficient induction of platelet aggregation in heparinized platelet-rich plasma by diadenosine triphosphate (Ap3A)
10. Role of red cells in preventing the growth of platelet aggregation
11. Comparison of the effect of heparin and citrate on platelet aggregation
12. Diadenosine 5′, 5‴-P1, P3-triphosphate in eukaryotic cells: identification and quantitation
13. Heparin inhibits PGE1-sensitive adenylate cyclase and antagonizes PGE1 antiaggregating effect in human platelets
14. Molecular events involved in the proaggregating effect of heparin on human platelets
15. Ungeklärte Fragen zu Heparin
16. A new method for the quantitative detection of platelet aggregates in patients with arterial insufficiency
17. Heparin and platelet function