Camptothecin induces protein-linked DNA breaks via mammalian DNA topoisomerase I

Journal of Biological Chemistry

Volumn 260, Issue 27, 1985, Pages 14873-14878

  Hsiang, Y H ^a   Hertzberg, R ^a   Hecht, S ^a   Liu, L F ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMSACRINE; CAMPTOTHECIN; DNA TOPOISOMERASE; NSC 100800; PROTEIN; TENIPOSIDE; UNCLASSIFIED DRUG;

CALF; CAMPTOTHECIN SODIUM; CATALYSIS; CHEMICAL MUTAGENESIS; CHROMOSOME; DNA STRAND BREAKAGE; DRUG EFFICACY; HELA CELL; HEREDITY; NONHUMAN; PRIORITY JOURNAL; THYMUS;

ANIMAL; BINDING SITES; CAMPTOTHECIN; CATTLE; DNA; DNA TOPOISOMERASES, TYPE I; DNA TOPOISOMERASES, TYPE II; DNA, SINGLE-STRANDED; HELA CELLS; HUMAN; KINETICS; MODELS, BIOLOGICAL; PLASMIDS; PROTEIN BINDING; SUPPORT, U.S. GOV'T, P.H.S.; THYMUS GLAND;

EID: 0022340594     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (0)